DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dyrk3 and AT1G13350

DIOPT Version :9

Sequence 1:	NP_001033810.1	Gene:	Dyrk3 / 3885567	FlyBaseID:	FBgn0027101	Length:	828	Species:	Drosophila melanogaster
Sequence 2:	NP_001321965.1	Gene:	AT1G13350 / 837895	AraportID:	AT1G13350	Length:	834	Species:	Arabidopsis thaliana

Alignment Length:	614	Identity:	166/614 - (27%)
Similarity:	269/614 - (43%)	Gaps:	70/614 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 NNHIELSETPATDKNNLNTTHLENTQLSKALSPPTSLPQIQIQMINQNLTHTGIAQNNTEKANRH 73
            |.|...|......:.|:..|.::|......:.........::.:|.::...|   |...||..:.
plant   255 NGHDPNSGDVKETRGNVERTRIDNDDKGDVVVWEVEQEDEELNLIEESRRRT---QAIMEKYKKK 316

  Fly    74 QYRDSGLQYLTRCFEPLAMLNDSKEDFPTQPSNNIANYPGDIQILPIFDCCEISES---IQAISL 135
            ..:.:|..     ...|.:.|..|:      |:.:|:..|...:.|:......:::   |.|:..
plant   317 LEQQNGFS-----SHDLELANIPKQ------SSTVADVLGSGTLGPVTSAVNQAKAGLDIDAVDG 370

  Fly   136 PNVTSPSKTKDVPGLFL-----RTISENSKSKSEPECESLISVKESSVMENHTFLFHEQIIMSGQ 195
            ......|...:.|...:     ||::.....:..|:.:    :.:....::   :|.|....|.:
plant   371 EVAKLSSAVGESPAQLVISDSDRTLASTGLGEGSPKDK----ISDDMFTDD---IFGESPADSQK 428

  Fly   196 QKCELHEKPKVLVV----SPQQVMILYMNKLTPYERTEILTYPQIYFIGANAKKRPG---VYGPN 253
            ..|.|.:...::.:    |.....:..::.||.|.|.. |.:....|:|....|..|   |....
plant   429 MVCTLTQIIDLVFIEFSNSGFICFVFPVHHLTRYSRNG-LPFVHYIFVGYLRGKGNGIPIVRSGL 492

  Fly   254 NSEYDNEQGAYIHVPHDHVAYRYEMLKIIGKGSFGQVIKAYDHKTH----EHVALKIVRNEKRFH 314
            :..:|:.:|.|.:...:.:..|||::...|||.|..|::|.|.|..    |.||:||:||.:..|
plant   493 DDNWDDAEGYYSYQLGELLDDRYEIMATHGKGVFSTVVRAKDTKAELGEPEEVAIKIIRNNETMH 557

  Fly   315 RQAQEEIRILHHLRRHDKYNTMNIIHMFDYFTFRNHTCITFELLSINLYELIKKNGFK-GFSLQL 378
            :..|.||:||..|...|..|..:.:.....|.:|||.|:.||.|.:||.|::||.|.. |..|..
plant   558 KAGQTEIQILKKLAGSDPENKRHCVRFLSTFKYRNHLCLVFESLHLNLREIVKKYGRNIGIQLSG 622

  Fly   379 VRKFAHSLLQCLDALYKNDIIHCDMKPENVLLKQQGRSGIKVIDFGSSCFE-NQRIYTYIQSRFY 442
            ||.:|..|...|..|....::|||:||:|:|: .:||:.:|:.||||:.|. ...:..|:.||||
plant   623 VRVYATQLFISLKHLKNCGVLHCDIKPDNMLV-NEGRNTLKLCDFGSAMFAGTNEVTPYLVSRFY 686

  Fly   443 RAPEVILGGKYGRAIDMWSLGCILAELLSGHALFPGENESDQLACIIEVLGMPNKNILASSKRSK 507
            ||||:|||..|...:|:||:||.|.||.||..:|||...::.|...:|:.|...|.:|    |..
plant   687 RAPEIILGLPYDHPLDIWSVGCCLYELFSGKIMFPGSTNNEMLRLHMELKGAFPKKML----RKG 747

  Fly   508 SFFSPKGYPRYCTVRTMSDG--------MVVLIGGQSRRGKQRGPPCSKSL----SKALDGCKDP 560
            :|.........|...|..|.        |:|.|     :.|:.|....:..    ||.|...:|.
plant   748 AFIDQHFDKDLCFYATEEDSVTRKTTKRMMVNI-----KPKEFGSVIKQRYKDEDSKLLVHFRDL 807

  Fly   561 LFLNFIRGCLEWDADKRLTPSEALKHPWL 589
            |...||     .|..||:|.|:||.||::
plant   808 LDRIFI-----LDPQKRITVSQALAHPFI 831

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dyrk3	NP_001033810.1	PKc_DYRK2_3	211..589	CDD:271126	134/398 (34%)
Dyrk3	NP_001033810.1	S_TKc	276..589	CDD:214567	120/330 (36%)
AT1G13350	NP_001321965.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D870358at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820