Protein Alignment Dyrk3 and YAK1

DIOPT Version :10

• Sequence 1: NP_001033810.1
• Gene: Dyrk3 / 3885567
• FlyBaseID: FBgn0027101
• Length: 828
• Species: Drosophila melanogaster
• Sequence 2: NP_198447.2
• Gene: YAK1 / 833590
• AraportID: AT5G35980
• Length: 956
• Species: Arabidopsis thaliana
• Alignment Length: 655
• Identity: 200/655 - (30%)
• Similarity: 306/655 - (46%)
• Gaps: 137/655 - (20%)

  Fly   205 KVLVVSPQQVMILYMNKLTPYERTEILTY----PQIYFIGANAKKR----PGVYGPNNSEYDNEQ 261
            ||.|...:.|::    :||   |..:.||    ||..:.|....||    |.| |.||..:||..
plant    46 KVHVAVKKPVVV----RLT---RDLVETYKICDPQFKYRGELNPKRYLTTPSV-GVNNDGFDNVN 102

  Fly   262 GAYIHVPHDHVA-----YRYEMLKIIGKGSFGQVIKAYDHKTHEHVALKIVRNEKRFHRQAQEEI 321
            ...|...:|...     .||.:..::|.|:||||.|.:..:|:..||:|:::|:..:::||..|:
plant   103 YDLILAVNDDFCSSDSRQRYIVKDLLGHGTFGQVAKCWVPETNSFVAVKVIKNQLAYYQQALVEV 167

  Fly   322 RILHHL-RRHDKYNTMNIIHMFDYFTFRNHTCITFELLSINLYELIKKNGFKGFSLQLVRKFAHS 385
            .||..| :::|..:..:|:.::|||..::|.||.||||.:|||||||.|.|:|.||.:|:.|:..
plant   168 SILTTLNKKYDPEDKNHIVRIYDYFLHQSHLCICFELLDMNLYELIKINQFRGLSLSIVKLFSKQ 232

  Fly   386 LLQCLDALYKNDIIHCDMKPENVLLKQQGR-SGIKVIDFGSSCFENQRIYTYIQSRFYRAPEVIL 449
            :|..|..|....|||||:||||:||....: :.||:|||||:|.|::.:|:|||||:||:|||:|
plant   233 ILLGLALLKDAGIIHCDLKPENILLCASVKPTEIKIIDFGSACMEDKTVYSYIQSRYYRSPEVLL 297

  Fly   450 GGKYGRAIDMWSLGCILAELLSGHALFPGENESDQLACIIEVLG-MPNKNILASSKRSKSFFSPK 513
            |.:|..||||||.|||:|||..|..||||.:|.|.|..:||:|| .|...:|..:|.:..||...
plant   298 GYQYTTAIDMWSFGCIVAELFLGLPLFPGGSEFDILRRMIEILGKQPPDYVLKEAKNTNKFFKCV 362

  Fly   514 GYPRYCTVRTMSDG---------MVVLIGGQSRRGKQRGPPCS------KSLSKAL--------- 554
            |     :|..:.:|         .:.|.|.:....:::.|...      |:|.:.:
plant   363 G-----SVHNLGNGGTYGGLKSAYMALTGEEFEAREKKKPEIGKEYFNHKNLEEIVKSYPYKINL 422

  Fly   555 ---DGCKDP----LFLNFIRGCLEWDADKRLTPSEALKHPWLRRR---LP-RPPSSSSGCGGVSG 608
               |..|:.    ..::|::|.:|:|..||.:|.:|.|||::...   .| .||.
plant   423 PEDDVVKETQIRLALIDFLKGLMEFDPAKRWSPFQAAKHPFITGEPFTCPYNPPP---------- 477

  Fly   609 LCSSRNESP---VT---------GQNRNFAAETTASSTSATSI---------SLTIKRENSHSSL 652
                  |:|   ||         |:...|||..:...:..|.|         .:.....||:.|:
plant   478 ------ETPRVHVTQNIKVDHHPGEGHWFAAGLSPHVSGRTRIPMHNSPHFQMMPYSHANSYGSI 536

  Fly   653 ----RLHHGAVPETDFKLIKSVPEGSSTATKEPMMNSDILPESFRQTTVVSPSKHSADSGGMSCL 713
                ..:.|.:.:..:......  |:..|...|               |..|..:..:.||:|.|
plant   537 GSYGSYNDGTIQDNSYGSYGGT--GNMFAYYSP---------------VNHPGLYMQNQGGVSML 584

  Fly   714 SAVDVGPSRYYPYMNNNENNRLFSSSLNSSANSLSHLEQATKLDALGEYSASTTPNLLSKNTGYS 778
            ........|...|.:.|..|.|.:|   .||.:.:.|       .||     |:|:..:.||...
plant   585 GTSPDARRRVMQYPHGNGPNGLGTS---PSAGNFAPL-------PLG-----TSPSQFTPNTNNQ 634

  Fly   779 FNSGS 783
            |.:||
plant   635 FLAGS 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dyrk3	NP_001033810.1	PKc_DYRK2_3	211..589	CDD:271126	153/424 (36%)
YAK1	NP_198447.2	PKc_YAK1	122..464	CDD:271114	132/346 (38%)