DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dyrk3 and AT3G53640

DIOPT Version :9

Sequence 1:	NP_001033810.1	Gene:	Dyrk3 / 3885567	FlyBaseID:	FBgn0027101	Length:	828	Species:	Drosophila melanogaster
Sequence 2:	NP_190932.1	Gene:	AT3G53640 / 824532	AraportID:	AT3G53640	Length:	642	Species:	Arabidopsis thaliana

Alignment Length:	386	Identity:	134/386 - (34%)
Similarity:	190/386 - (49%)	Gaps:	52/386 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   220 NKLTPYERTEILTYPQIYFIGANAKKRPGVYGPNNSEYDNEQGAYIHVPHDHVAYRYEMLKIIGK 284
            |.|.|:.|:.:                       |..:|:.:|.|.:...:.:..|||::...||
plant   290 NALVPFVRSGL-----------------------NDNWDDAEGYYSYQLGELLDDRYEIMATHGK 331

  Fly   285 GSFGQVIKAYDHKTH----EHVALKIVRNEKRFHRQAQEEIRILHHLRRHDKYNTMNIIHMFDYF 345
            |.|..|::|.|.|..    |.||:||:|..:..|:..|.|||||..|...|..|..:.:.:...|
plant   332 GVFSTVVRAKDTKPELGEPEEVAIKIIRKNETMHKAGQAEIRILKKLVCSDPENKHHCVRLLSTF 396

  Fly   346 TFRNHTCITFELLSINLYELIKKNGFK-GFSLQLVRKFAHSLLQCLDALYKNDIIHCDMKPENVL 409
            .:|||.|:.||.|.:||.|::||.|.. |..|..||.:|..|...|..|....::|||:||:|:|
plant   397 EYRNHLCLVFESLHLNLREVVKKIGVNIGLKLYDVRVYAEQLFISLKHLKNCGVLHCDIKPDNIL 461

  Fly   410 LKQQGRSGIKVIDFGSSCF--ENQRIYTYIQSRFYRAPEVILGGKYGRAIDMWSLGCILAELLSG 472
            : .:||:.:|:.||||:.|  ||| :..|:.||||||||:|||..|...:|:||:||.|.||.||
plant   462 M-NEGRNMLKLCDFGSAMFAGENQ-VTPYLVSRFYRAPEIILGLPYDHPLDIWSVGCCLYELYSG 524

  Fly   473 HALFPGENESDQLACIIEVLGMPNKNILASSKRSKSFFSPKGYPRYCTVRTMSDGMVVLIGGQSR 537
            ..:|||...:|.|...:|:.|...|.:|    |..:|.........|...|..|.:.   |...|
plant   525 KIMFPGSTNNDMLRLHMELKGPFPKKML----RKGAFIDQHFDKDLCFYATEEDSVT---GKTIR 582

  Fly   538 RGKQRGPPCSKSLSKAL-----DGCKDPLFLNFIRGCLE----WDADKRLTPSEALKHPWL 589
            |......|  |.|...:     |  :||..|...|..|:    .|..||||.|:||.||::
plant   583 RIMVNVKP--KDLGSVIRRRYED--EDPKVLVHFRNLLDKIFTLDPQKRLTVSQALAHPFI 639

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dyrk3	NP_001033810.1	PKc_DYRK2_3	211..589	CDD:271126	134/384 (35%)
Dyrk3	NP_001033810.1	S_TKc	276..589	CDD:214567	125/328 (38%)
AT3G53640	NP_190932.1	U79_P34	<75..130	CDD:281109
		STKc_PRP4	322..639	CDD:271037	126/329 (38%)
		S_TKc	323..639	CDD:214567	125/328 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D870358at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820