DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dyrk3 and AT3G25840

DIOPT Version :9

Sequence 1:	NP_001033810.1	Gene:	Dyrk3 / 3885567	FlyBaseID:	FBgn0027101	Length:	828	Species:	Drosophila melanogaster
Sequence 2:	NP_189213.2	Gene:	AT3G25840 / 822178	AraportID:	AT3G25840	Length:	935	Species:	Arabidopsis thaliana

Alignment Length:	599	Identity:	155/599 - (25%)
Similarity:	255/599 - (42%)	Gaps:	104/599 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 ELSETPATDKNNLNTTHLENTQLSKALSPPTSLPQIQIQMINQNLTHTGIA-----QNNTEKANR 72
            :|.||.|.|:.:.|....::.........|....:..:..|.:.......|     :...|:.|.
plant   416 KLEETWANDERSRNEDGQDDNDEGLTWKSPEEEEEELLNRIKEESRKRMEAILEKHKRKPEQQNE 480

  Fly    73 HQYRDSGLQYLTRCFEPLAMLNDSKEDFPTQPSNNIANYPGDIQILPIFDCCEISESIQAISLPN 137
            ...:|:|...:.....|::          |.|:..||...|..:....||.......:.|...|.
plant   481 LLTQDNGKDIVPETGAPVS----------TSPAVVIAANVGQAKTNLDFDTVAAKAPLIAGGPPT 535

  Fly   138 VTSPSKTKDVPGLFLRTISENSKSKSEPECESLISVKESS-VMENHTFLFHEQIIMSGQQKCELH 201
            ::.              ||::.|::::      ..:.|.| ..|....:||:.|.  |:....:.
plant   536 MSG--------------ISDSEKNQAQ------AGLGEGSPKSERSADMFHDDIF--GESPAGIR 578

  Fly   202 EKPKVLVVSPQQVMILYMNKLTPYERTEILTYPQIYFIGANAKKRPGVYGPNNSEYDNEQGAYIH 266
            :                                    :|......|.|....:..:|:.:|.|.:
plant   579 K------------------------------------VGGKGDGVPMVRSGLHDNWDDAEGYYSY 607

  Fly   267 VPHDHVAYRYEMLKIIGKGSFGQVIKAYDHKT----HEHVALKIVRNEKRFHRQAQEEIRILHHL 327
            ...:.:..|||::...|||.|..|::|.|.|.    .|.||:||:||.:..|:..:.|::||..|
plant   608 QFGELLDGRYEVIATHGKGVFSTVVRAKDLKAGPAEPEEVAIKIIRNNETMHKAGKIEVQILKKL 672

  Fly   328 RRHDKYNTMNIIHMFDYFTFRNHTCITFELLSINLYELIKKNGFK-GFSLQLVRKFAHSLLQCLD 391
            ...|:.:..:.:.....|.:|||.|:.||.|.:||.|::||.|.. |..|..||.::..|...|.
plant   673 AGADREDRRHCVRFLSSFKYRNHLCLVFESLHLNLREVLKKFGRNIGLQLSAVRAYSKQLFIALK 737

  Fly   392 ALYKNDIIHCDMKPENVLLKQQGRSGIKVIDFGSSCFENQRIYT-YIQSRFYRAPEVILGGKYGR 455
            .|....::|||:||:|:|: .:|::.:|:.|||::.|..:...| |:.|||||:||:|||..|..
plant   738 HLKNCGVLHCDIKPDNMLV-NEGKNVLKLCDFGNAMFAGKNEVTPYLVSRFYRSPEIILGLTYDH 801

  Fly   456 AIDMWSLGCILAELLSGHALFPGENESDQLACIIEVLG-MPNKNILASSKRSKSFFSPKGYPRYC 519
            .:|:||:||.|.||.||..||||...:|.|...:|:.| .|.|.:...:...:.|.....:  |.
plant   802 PLDIWSVGCCLYELYSGKVLFPGATNNDMLRLHMELKGPFPKKMLRKGAFIDQHFDHDLNF--YA 864

  Fly   520 TVRTMSDG-----MVVLIGGQSRRGKQRGPPCSKSLSKALDGCKDPLFLNFIRGCLE----WDAD 575
            |......|     |:|.:     :.|..|     |:.|...| :||..|...|..|:    .|.:
plant   865 TEEDTVSGKLIKRMIVNV-----KPKDFG-----SIIKGYPG-EDPKILAHFRDLLDKMFILDPE 918

  Fly   576 KRLTPSEALKHPWL 589
            :|||.|:||.||::
plant   919 RRLTVSQALAHPFI 932

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dyrk3	NP_001033810.1	PKc_DYRK2_3	211..589	CDD:271126	122/393 (31%)
Dyrk3	NP_001033810.1	S_TKc	276..589	CDD:214567	115/328 (35%)
AT3G25840	NP_189213.2	PRP38_assoc	186..266	CDD:289628
		DUF1777	315..>439	CDD:285811	6/22 (27%)
		STKc_PRP4	616..932	CDD:271037	116/329 (35%)
		S_TKc	617..932	CDD:214567	115/328 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810