Protein Alignment Dyrk3 and hipk1b

DIOPT Version :9

• Sequence 1: NP_001033810.1
• Gene: Dyrk3 / 3885567
• FlyBaseID: FBgn0027101
• Length: 828
• Species: Drosophila melanogaster
• Sequence 2: XP_009304049.1
• Gene: hipk1b / 572323
• ZFINID: ZDB-GENE-140324-1
• Length: 1126
• Species: Danio rerio
• Alignment Length: 546
• Identity: 166/546 - (30%)
• Similarity: 264/546 - (48%)
• Gaps: 75/546 - (13%)

  Fly   240 GANAKKRPGVYGPNNSEYDNEQGAYIHVPHD---HVAYRYEMLKIIGKGSFGQVIKAYDHKTHEH 301
            |...:..|.......|...|.:|.|..|.|:   .|:..||:|:.:|:|:||||.|.:...|:|.
Zfish   147 GTTGQSIPHSAPTTKSSSSNGEGDYQLVQHEILCSVSNSYEVLEFLGRGTFGQVAKCWKRGTNEI 211

  Fly   302 VALKIVRNEKRFHRQAQEEIRILHHLRRHDKYNTMNIIHMFDYFTFRNHTCITFELLSINLYELI 366
            ||:||::|...:.||.|.|:.||:.|.. :..:..|.:..::.|..:.|||:.||:|..|||:.:
Zfish   212 VAIKILKNHPSYARQGQIEVSILNRLSA-ENADEFNFVRSYECFQHKGHTCLVFEMLEQNLYDFL 275

  Fly   367 KKNGFKGFSLQLVRKFAHSLLQCLDALYKNDIIHCDMKPENVLL----KQQGRSGIKVIDFGSSC 427
            |.:.|....|:.:|.....:...|..|....:||.|:||||::|    :|..|  :|||||||:.
Zfish   276 KHSKFSPLPLRHIRPILQQVATALMKLKCLGLIHADLKPENIMLVDPIRQPYR--VKVIDFGSAS 338

  Fly   428 FENQRI-YTYIQSRFYRAPEVILGGKYGRAIDMWSLGCILAELLSGHALFPGENESDQLACIIEV 491
            ..::.: .||:|||:|||||:|||..:..|||||||||::|||..|..|:||.:|.||:..|.:.
Zfish   339 HVSKAVCSTYLQSRYYRAPEIILGLPFCEAIDMWSLGCVIAELFLGWPLYPGASEYDQIRYISQT 403

  Fly   492 LGMPNKNILASSKRSKSFFS---PKGYPRYCTVRTMSDGMVVLIGGQSRRGKQRGPPCSKSLSKA 553
            .|:|.:.:|::..::..||:   ...||.: .::|.|:       .:|..|.:     ||...|.
Zfish   404 QGLPPEYLLSAGTKTSRFFNRGPDSSYPLW-RLKTPSE-------HESEMGIK-----SKEARKY 455

  Fly   554 LDGCKDPL-----------------------FLNFIRGCLEWDADKRLTPSEALKHPW--LRRRL 593
            :..|.|.:                       .::.::..|..|||||:||::.|.||:  :...|
Zfish   456 IFNCLDDMMQVNLPNHLEGTDLLAEKADRRELIDLLKRMLRLDADKRITPTKTLAHPFVTMSHLL 520

  Fly   594 PRPPSSS-SGCGGVSGLCSSRNESPVTGQNRNFAAETTASSTSATSISLTIKRE-NSHSSLRLHH 656
            ..|.||. ..|.....:|..||.|..:|: ..|||.|...  :|.::::|...: |.||.:....
Zfish   521 NFPHSSHVKSCFQNMDICKRRNNSFDSGK-ALFAANTVPG--TAGNLTVTFSSQLNQHSQVPSAG 582

  Fly   657 GAVPETDFKLIKSVPEGSSTAT-KEPMMNSDILP------------ESFRQTTVVSPSKHSADSG 708
            ||||     |:...|.....|| ..|.:....:|            |.|:||.:|.|........
Zfish   583 GAVP-----LLNYQPALYQQATINIPGLAQPSIPLQTRSTQLCAQTEPFQQTLIVCPPTTIQGLP 642

  Fly   709 GMSCLSAVDVGPSRYYPYMNNNENNR 734
            ..:..|:..|......|.:..|::::
Zfish   643 SSNKTSSYPVRMENGVPVVQQNQSSQ 668

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dyrk3	NP_001033810.1	PKc_DYRK2_3	211..589	CDD:271126	127/384 (33%)
		S_TKc	276..589	CDD:214567	118/345 (34%)
hipk1b	XP_009304049.1	STKc_HIPK	186..514	CDD:271113	118/343 (34%)
		S_TKc	186..514	CDD:214567	118/343 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810