Protein Alignment Dyrk3 and Doa

DIOPT Version :9

• Sequence 1: NP_001033810.1
• Gene: Dyrk3 / 3885567
• FlyBaseID: FBgn0027101
• Length: 828
• Species: Drosophila melanogaster
• Sequence 2: NP_001014681.2
• Gene: Doa / 43415
• FlyBaseID: FBgn0265998
• Length: 2045
• Species: Drosophila melanogaster
• Alignment Length: 667
• Identity: 163/667 - (24%)
• Similarity: 284/667 - (42%)
• Gaps: 170/667 - (25%)

  Fly    42 PTSLPQIQIQMINQNLTHTGIAQNNTEKANRHQYRDSGLQYLTRCFEPLAMLNDSKEDFPTQPSN 106
            ||:|   |....:|...|....|.:.:: .:||:...|:..::|.:..:....:.|   |.|..:
  Fly  1494 PTAL---QFHQQHQQQQHLQQQQQHPQQ-QQHQHSSFGVGMMSRNYYNMPKQPERK---PLQTFD 1551

  Fly   107 NIANYPGDIQILPIFDCCEISESIQ-----------------AISL---PNVTSPSKTKDVPGLF 151
            ..| ||...|:.|:    :..:..|                 |..|   ||..:.        ||
  Fly  1552 PYA-YPKPNQMQPV----KYQQQQQHPHTQFQNASAGGGGGGAAGLQYDPNTNTQ--------LF 1603

  Fly   152 LRTISENSKSKSEPECESLISVKESSVMENHTFLFHEQIIMSGQQKCELHEKPKVLVVSPQQVMI 216
            ..:.:.:|.:|...:.:.....::|.:.::::.:|:.    ||||    |:        |.|...
  Fly  1604 YASPASSSSNKQPQQPQQQQQQQQSQLQQSNSVIFNH----SGQQ----HQ--------PHQQQQ 1652

  Fly   217 LYMNKLTPYERTEILTYPQIYFIGANAKKRPGVYGPNNSEYDNEQGAYIHVPHDHVAYRYEMLKI 281
            ..|:|          :...::||   ...:|.:       .|:..|..|:...|.:.:||:::..
  Fly  1653 NEMSK----------SALGLHFI---ETAKPVI-------QDDADGHLIYHTGDILHHRYKIMAT 1697

  Fly   282 IGKGSFGQVIKAYDHKTHEHVALKIVRNEKRFHRQAQEEIRILHHLRRHDKYNTMNIIHMFDYFT 346
            :|:|:||:|:|..|.:....:||||::|.:::...|:.||..|..:.:.|.:.....:.|.|:|.
  Fly  1698 LGEGTFGRVVKVKDMERDYCMALKIIKNVEKYREAAKLEINALEKIAQKDPHCDHLCVKMIDWFD 1762

  Fly   347 FRNHTCITFELLSINLYELIKKNGFKGFSLQLVRKFAHSLLQCLDALYKNDIIHCDMKPENVL-- 409
            :..|.||.||:|.:::::.:::|.::.:.|..||..|:.|...:..|:.|.:.|.|:||||:|
  Fly  1763 YHGHMCIVFEMLGLSVFDFLRENNYEPYPLDQVRHMAYQLCYSVKFLHDNRLTHTDLKPENILFV 1827

  Fly   410 ---------------LKQQGRSGIKVIDFGSSCFENQRIYTYIQSRFYRAPEVILGGKYGRAIDM 459
                           :::...:.:::|||||:.|:::...|.:.:|.||||||||...:.:..|:
  Fly  1828 DSDYTSHYNHKINREVRRVKNTDVRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDV 1892

  Fly   460 WSLGCILAELLSGHALFPGENESDQLACIIEVLG-----MPNKNILASSKRSKSFFSPKGYPRYC 519
            ||:||||.||..|..||...:..:.||.:..:||     |...:.|.|..::|.|:
  Fly  1893 WSIGCILFELYLGITLFQTHDNREHLAMMERILGQIPYRMARNHTLYSKTKTKYFY--------- 1948

  Fly   520 TVRTMSDGMVVLIGGQSRRGKQRGPPCSKSLSKALDGCKDPLFL-------------NFIRGCLE 571
                              .||......|.:.....|.|| ||||             :.|:..||
  Fly  1949 ------------------HGKLDWDEKSSAGRYVRDHCK-PLFLCQLSDSEDHCELFSLIKKMLE 1994

  Fly   572 WDADKRLTPSEALKHPWLRRRLPRPPSSSSGCGGVSGLCSSRNESPVTGQNRNFAAETTASSTSA 636
            ::...|:|..|||.||:..|   .||...  .|.||      |:.|:             ||.|:
  Fly  1995 YEPSSRITLGEALHHPFFDR---LPPHHR--VGEVS------NKQPL-------------SSGSS 2035

  Fly   637 TSISLTIKRENSHSSLR 653
            :       ||.|||..|
  Fly  2036 S-------RERSHSLSR 2045

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dyrk3	NP_001033810.1	PKc_DYRK2_3	211..589	CDD:271126	111/412 (27%)
		S_TKc	276..589	CDD:214567	99/347 (29%)
Doa	NP_001014681.2	PKc_CLK	1679..2012	CDD:271036	102/360 (28%)
		S_TKc	1692..2012	CDD:214567	99/347 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460708
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740