Protein Alignment Dyrk3 and Clk4

DIOPT Version :10

• Sequence 1: NP_001033810.1
• Gene: Dyrk3 / 3885567
• FlyBaseID: FBgn0027101
• Length: 828
• Species: Drosophila melanogaster
• Sequence 2: XP_038941309.1
• Gene: Clk4 / 287269
• RGDID: 1310274
• Length: 507
• Species: Rattus norvegicus
• Alignment Length: 375
• Identity: 117/375 - (31%)
• Similarity: 192/375 - (51%)
• Gaps: 57/375 - (15%)

  Fly   241 ANAKKRPGVYGPNNSEYDNEQGAYIHVPHDHVAYRYEMLKIIGKGSFGQVIKAYDHKTHE-HVAL 304
            ::.:||      :.|..|:|:|..|....|.:..|||::..:|:|:||:|::..||.... |||:
  Rat   156 SHRRKR------SRSIEDDEEGHLICQSGDVLRARYEIVDTLGEGAFGKVVECIDHGMDGLHVAV 214

  Fly   305 KIVRNEKRFHRQAQEEIRILHHLRRHDKYNTMNIIHMFDYFTFRNHTCITFELLSINLYELIKKN 369
            |||:|..|:...|:.||::|.||...|..:....:.|.::|....|.||.||||.::.|:.||:|
  Rat   215 KIVKNVGRYREAARSEIQVLEHLNSTDPNSVFRCVQMLEWFDHHGHVCIVFELLGLSTYDFIKEN 279

  Fly   370 GFKGFSLQLVRKFAHSLLQCLDALYKNDIIHCDMKPENVL-------------LKQQGR----SG 417
            .|..|.:..:|:.|:.:.|.::.|:.|.:.|.|:||||:|             :|:..|    :.
  Rat   280 SFLPFQIDHIRQMAYQICQSINFLHHNKLTHTDLKPENILFVKSDYVVKYNSKMKRDERTLKNTD 344

  Fly   418 IKVIDFGSSCFENQRIYTYIQSRFYRAPEVILGGKYGRAIDMWSLGCILAELLSGHALFPGENES 482
            |||:||||:.::::...|.:.:|.||||||||...:.:..|:||:||||.|...|..:|...:..
  Rat   345 IKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTVFQTHDSK 409

  Fly   483 DQLACIIEVLGMPNKNILASSKRSKSF---------FSPKGYPRYCTVRTMSDGMVVLIGGQSRR 538
            :.||.:..:||....:::..:::.|.|         .|..|  ||.
  Rat   410 EHLAMMERILGPIPAHMIQKTRKRKYFHHNQLDWDEHSSAG--RYV------------------- 453

  Fly   539 GKQRGPPCSKSLSKALDGCKDPLFLNFIRGCLEWDADKRLTPSEALKHPW 588
             ::|..|. |......|...:.|| :.:|..||:|..||:|..|||:||:
  Rat   454 -RRRCKPL-KEFMLCHDEEHEKLF-DLVRRMLEYDPTKRITLDEALQHPF 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dyrk3	NP_001033810.1	PKc_DYRK2_3	211..589	CDD:271126	117/375 (31%)
Clk4	XP_038941309.1	PKc_CLK1_4	172..501	CDD:271115	111/353 (31%)