Protein Alignment Dyrk3 and pom1

DIOPT Version :9

• Sequence 1: NP_001033810.1
• Gene: Dyrk3 / 3885567
• FlyBaseID: FBgn0027101
• Length: 828
• Species: Drosophila melanogaster
• Sequence 2: NP_592974.1
• Gene: pom1 / 2541889
• PomBaseID: SPAC2F7.03c
• Length: 1087
• Species: Schizosaccharomyces pombe
• Alignment Length: 706
• Identity: 247/706 - (34%)
• Similarity: 355/706 - (50%)
• Gaps: 136/706 - (19%)

  Fly     2 VGSQEKKNNHIELSETPATDKNN--LNTTHLENTQLSKALSP------PTSLPQIQIQMI----- 53
            ||||.|.::.    .||:...||  :::.:..||..|..:.|      |.:.|:...|..
pombe   340 VGSQTKSHSF----ATPSVFDNNKPVSSDNHNNTTTSSQVHPDSRNPDPKAAPKAVSQKTNVDGH 400

  Fly    54 -NQNLTHTGIAQN--NTEKANRHQYRDSGLQYLTR-CFE-----------------------PLA 91
             |....|....||  .::|::..:.|.|...:.:| .|.                       |.|
pombe   401 RNHEAKHGNTVQNESKSQKSSNKEGRSSRGGFFSRLSFSRSSSRMKKGSKAKHEDAPDVPAIPHA 465

  Fly    92 MLNDS--KEDF------PTQPSNNIANY--------------------PGDIQILPIFDCCEISE 128
            .:.||  |..:      ||:..:.:..:                    |..:..|.|.......|
pombe   466 YIADSSTKSSYRNGKKTPTRTKSRMQQFINWFKPSKERSSNGNSDSASPPPVPRLSITRSQVSRE 530

  Fly   129 SIQAISLPNVTS-PSKTKD---VPGLFLRTISENSKSKSEPECESL---ISVKESSVMENHTFLF 186
            ..:...:|:|.. ||..||   ||.  .|::|...|..|:.. |||   :|...|:|:...   |
pombe   531 PEKPEEIPSVPPLPSNFKDKGHVPQ--QRSVSYTPKRSSDTS-ESLQPSLSFASSNVLSEP---F 589

  Fly   187 HEQI------IMSGQQKCELHEKPKVL--------VVSP---QQVMILYMNKLTPYERTEILTYP 234
            ..::      .::.::..:|.:..||:        :::|   .:|.::....||.||:.||..|.
pombe   590 DRKVADLAMKAINSKRINKLLDDAKVMQSLLDRACIITPVRNTEVQLINTAPLTEYEQDEINNYD 654

  Fly   235 QIYFIG-ANAKKRPGV--YGPNNSEYDNEQGAYIHVPHDHVAYRYEMLKIIGKGSFGQVIKAYDH 296
            .|||.| .|..||...  ...:|..:|:|:|.|..|..||:|||||::..:||||||||::..|:
pombe   655 NIYFTGLRNVDKRRSADENTSSNFGFDDERGDYKVVLGDHIAYRYEVVDFLGKGSFGQVLRCIDY 719

  Fly   297 KTHEHVALKIVRNEKRFHRQAQEEIRILHHLRRHDKYNTMNIIHMFDYFTFRNHTCITFELLSIN 361
            :|.:.|||||:||:||||.||..|.:||..:|..|..:...::...|:|.||:|.|:..|||..|
pombe   720 ETGKLVALKIIRNKKRFHMQALVETKILQKIREWDPLDEYCMVQYTDHFYFRDHLCVATELLGKN 784

  Fly   362 LYELIKKNGFKGFSLQLVRKFAHSLLQCLDALYKNDIIHCDMKPENVLLKQQGRSGIKVIDFGSS 426
            ||||||.|||||..:.:::.....|:|||..|.:..:||||:||||:||....:|.:||||||||
pombe   785 LYELIKSNGFKGLPIVVIKSITRQLIQCLTLLNEKHVIHCDLKPENILLCHPFKSQVKVIDFGSS 849

  Fly   427 CFENQRIYTYIQSRFYRAPEVILGGKYGRAIDMWSLGCILAELLSGHALFPGENESDQLACIIEV 491
            |||.:.:||||||||||:||||||..||..||:||||||:||:.:|..|||||||.:|||||:|:
pombe   850 CFEGECVYTYIQSRFYRSPEVILGMGYGTPIDVWSLGCIIAEMYTGFPLFPGENEQEQLACIMEI 914

  Fly   492 LGMPNKNILASSKRSKSFFSPKGYPRYCTVRTMSDGMVVLIGGQSRRGKQRGPPCSKSLSKALDG 556
            .|.|:.:::....|.|.||...|.||          ..|...|.|||      |.||||.:.|.
pombe   915 FGPPDHSLIDKCSRKKVFFDSSGKPR----------PFVSSKGVSRR------PFSKSLHQVLQ- 962

  Fly   557 CKDPLFLNFIRGCLEWDADKRLTPSEALKHPWL--------------RRRLPRPPS 598
            |||..||:||..||:||.|:|:||.:|.:|.:|              |::..|||:
pombe   963 CKDVSFLSFISDCLKWDPDERMTPQQAAQHDFLTGKQDVRRPNTAPARQKFARPPN 1018

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dyrk3	NP_001033810.1	PKc_DYRK2_3	211..589	CDD:271126	184/383 (48%)
		S_TKc	276..589	CDD:214567	157/312 (50%)
pom1	NP_592974.1	PKc_DYRK	685..995	CDD:271112	165/326 (51%)
		S_TKc	699..995	CDD:214567	157/312 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	353	1.000	Domainoid score	I168
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000895
OrthoInspector	1	1.000	-	-		mtm9290
orthoMCL	1	0.900	-	-		OOG6_100394
Panther	1	1.100	-	-	O	PTHR24058
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R968
SonicParanoid	1	1.000	-	-		X888
TreeFam	0	0.000	Not matched by this tool.
	9	8.840