Protein Alignment Dyrk3 and prpf-4

DIOPT Version :9

• Sequence 1: NP_001033810.1
• Gene: Dyrk3 / 3885567
• FlyBaseID: FBgn0027101
• Length: 828
• Species: Drosophila melanogaster
• Sequence 2: NP_001250391.1
• Gene: prpf-4 / 172443
• WormBaseID: WBGene00004186
• Length: 775
• Species: Caenorhabditis elegans
• Alignment Length: 569
• Identity: 154/569 - (27%)
• Similarity: 246/569 - (43%)
• Gaps: 71/569 - (12%)

  Fly    49 QIQMINQNLTHTGIAQNNTEKANRHQYRDSGLQYLTRCFEPLAMLNDSKEDFPTQPSNNIANYPG 113
            :||:|.:...||   :.||.:.:.....|:              :.|.|.|.....|::..:...
 Worm   243 RIQIIKKIEGHT---EENTPRDSSTPRSDT--------------IGDKKTDESEDSSSDSEDDED 290

  Fly   114 DIQILPIFDCCEI----SESIQAISLPNVTSPSKTKDVPGLFLRTISENSKSKSEPECESLISVK 174
            |.::....|..:.    ||.....|.|  .|.....|.|..|...:.:......:.:..::..|.
 Worm   291 DRKLAEAKDLIKSTRFGSEQGSGASTP--VSIQSDNDTPTDFFSGLRDKMVHMKDADEHNVDEVL 353

  Fly   175 ESSVMENHTFLFHEQIIMSGQQKCELHEKPKVLVVSPQQVM--------------ILYMNKLTPY 225
            :....|.:...:|.|  :..|:|.|..||.|.|........              :...|:..|.
 Worm   354 QRGKDEEYREDWHTQ--LKEQEKREEEEKKKKLEAEAAAEAAKKKKQEEDDTGFDMFADNEELPQ 416

  Fly   226 ERTEILTYPQIYFIGANAKKRPGVYGPNNSEYDNEQGAYIHVPHDHVAYRYEMLKIIGKGSFGQV 290
            :.|.|..:.     ||       |:......:|:.:|.|.....:.:..||.::...|.|.||.|
 Worm   417 DSTTIDGHS-----GA-------VHDTLKDNWDDVEGYYRVRIGELLDTRYRVVGFTGAGVFGNV 469

  Fly   291 IKAYDHKTHEHVALKIVRNEKRFHRQAQEEIRILHHLRRHDKYNTMNIIHMFDYFTFRNHTCITF 355
            .:..|......||:||:||.:..::....|:.:|..|...||.:..:.:.:|..|...||.|:.|
 Worm   470 CRCNDQTKGNTVAVKIIRNNEVMYKTGLRELEVLRKLNEADKEDKYHCLRLFRTFKHHNHLCLVF 534

  Fly   356 ELLSINLYELIKKNGFK-GFSLQLVRKFAHSLLQCLDALYKNDIIHCDMKPENVLLKQQGRSGIK 419
            |.||:||.||:||.|.| |..|:.||.:|..||..|..|.|.:.:|.|:||:|:|: .:.:..:|
 Worm   535 ENLSMNLRELLKKYGQKDGLHLKAVRSYAQQLLLALRLLKKLEFVHADIKPDNILV-NESKLTLK 598

  Fly   420 VIDFGSSCFEN-QRIYTYIQSRFYRAPEVILGGKYGRAIDMWSLGCILAELLSGHALFPGENESD 483
            :.||||:...| |.:..|:.||||||||::||.::..|||:||:...|.|:.:|..:|||...:.
 Worm   599 LCDFGSAGRVNEQELAPYLVSRFYRAPEIMLGVRHDYAIDLWSVAVTLYEVYTGKIMFPGRTNNH 663

  Fly   484 QLACIIEVLG-MPNKNILASSKRSKSFFSPKGYPRYCTVR-------TMSDGMVVLIGGQSRRGK 540
            .|....:|.| .|||.:      .||.|....:...|.:.       |..:.:.||...:..|..
 Worm   664 MLKLFTDVKGKYPNKLV------RKSQFKDTHFDVNCNLLYQEVDKVTERNKITVLANLKPTRDL 722

  Fly   541 QRGPPCSKSLSK-ALDGCKDPLFLNFIRGCLEWDADKRLTPSEALKHPW 588
            :......:.||: .:|..:  .|...:.|.|..|..||.|.:||||||:
 Worm   723 ESELIAGQRLSRDQMDQIQ--AFRTLLDGMLILDPSKRTTCNEALKHPF 769

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dyrk3	NP_001033810.1	PKc_DYRK2_3	211..589	CDD:271126	121/403 (30%)
		S_TKc	276..589	CDD:214567	110/324 (34%)
prpf-4	NP_001250391.1	STKc_PRP4	454..770	CDD:271037	111/325 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D870358at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920