Protein Alignment Dyrk3 and dyrk3

DIOPT Version :9

• Sequence 1: NP_001033810.1
• Gene: Dyrk3 / 3885567
• FlyBaseID: FBgn0027101
• Length: 828
• Species: Drosophila melanogaster
• Sequence 2: NP_001108400.1
• Gene: dyrk3 / 100141364
• ZFINID: ZDB-GENE-080219-31
• Length: 581
• Species: Danio rerio
• Alignment Length: 629
• Identity: 300/629 - (47%)
• Similarity: 384/629 - (61%)
• Gaps: 97/629 - (15%)

  Fly    25 LNTTHLENTQLSKALSPPTSLPQIQIQMINQNLTHTGIAQNNTEKANRHQYRDSGLQYLTRCFEP 89
            :.|.|:.|.........|:.||.:.        .|||:.:...:.   ||....|...:...:
Zfish    25 MRTDHIVNQDADVNGQSPSGLPPLP--------KHTGVIKPTMKD---HQAIRGGQMKVKYVY-- 76

  Fly    90 LAMLNDSKEDFPTQPSNNIANYPGDIQILPIFDCCEISESIQAISLPNVTSPSKTKDVPGLFLRT 154
                    ||...:..|.::.:.|..|:                  |....|:.:|:      |:
Zfish    77 --------EDSYNRKLNGVSQHNGTSQV------------------PAKPPPAISKE------RS 109

  Fly   155 ISENSKSKSEPECESLISVKESSVMENHTFLFHEQIIMSGQQKCELHEKPKVLVVSPQQVMILYM 219
            :..||..||          .|||.          ::...|..            ::|:|.:..:.
Zfish   110 VDSNSSVKS----------SESST----------KVTKLGSP------------MTPEQALKQHR 142

  Fly   220 NKLTPYERTEILTYPQIYFIGANAKKRPGVY-GPNNSEYDNEQGAYIHVPHDHVAYRYEMLKIIG 283
            .::|..|:.||..|.:|||:|.|||||..|. |.|||.||::||.||||||||:|||||.||:||
Zfish   143 QQMTTLEQQEIHNYSEIYFLGPNAKKRQAVAGGTNNSGYDDDQGGYIHVPHDHLAYRYEFLKVIG 207

  Fly   284 KGSFGQVIKAYDHKTHEHVALKIVRNEKRFHRQAQEEIRILHHLRRHDKYNTMNIIHMFDYFTFR 348
            |||||||.|.||||..:|||||||||||||||||.||||||.||::.||..:||::||.:.||||
Zfish   208 KGSFGQVAKVYDHKLQQHVALKIVRNEKRFHRQAAEEIRILEHLKKQDKTGSMNVVHMLENFTFR 272

  Fly   349 NHTCITFELLSINLYELIKKNGFKGFSLQLVRKFAHSLLQCLDALYKNDIIHCDMKPENVLLKQQ 413
            ||.|:||||||:|||||||:|.|:||||.||||||||:||||:||:::.|||||:||||:|||||
Zfish   273 NHICMTFELLSMNLYELIKRNKFQGFSLPLVRKFAHSILQCLEALHRHKIIHCDLKPENILLKQQ 337

  Fly   414 GRSGIKVIDFGSSCFENQRIYTYIQSRFYRAPEVILGGKYGRAIDMWSLGCILAELLSGHALFPG 478
            |||||||||||||||::||:|||||||||||||||||.:||..|||||.||||||||:|:.||||
Zfish   338 GRSGIKVIDFGSSCFDHQRVYTYIQSRFYRAPEVILGSRYGMPIDMWSFGCILAELLTGYPLFPG 402

  Fly   479 ENESDQLACIIEVLGMPNKNILASSKRSKSFFSPKGYPRYCTVRTMSDGMVVLIGGQSRRGKQRG 543
            |:|.|||||::|:||||...:|..:||:|:|.|.||:||||||.|:|:|.:||.|.:|||||.||
Zfish   403 EDEGDQLACMMELLGMPPSKLLEQAKRAKNFISSKGHPRYCTVSTLSNGTIVLNGSRSRRGKMRG 467

  Fly   544 PPCSKSLSKALDGCKDPLFLNFIRGCLEWDADKRLTPSEALKHPWLRRRLPRPPSSSSGCGGVSG 608
            .|.||....||.||:|..|::|::.||:||...|:||.:||:||||.:|||:|..     ||...
Zfish   468 APGSKEWGTALKGCEDATFIDFLKKCLDWDPSTRMTPVQALRHPWLYKRLPKPAP-----GGEKT 527

  Fly   609 LCSSR-------------NESPVTGQNRNFAAETTASSTSATSI 639
            :...|             ...||.|...| ...||....|..||
Zfish   528 VLPKRISEHSTSFPTIISKVPPVMGSTNN-KLRTTMMGDSTGSI 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dyrk3	NP_001033810.1	PKc_DYRK2_3	211..589	CDD:271126	253/378 (67%)
		S_TKc	276..589	CDD:214567	217/312 (70%)
dyrk3	NP_001108400.1	PKc_DYRK2_3	134..513	CDD:271126	253/378 (67%)
		S_TKc	200..513	CDD:214567	217/312 (70%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	504	1.000	Domainoid score	I325
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D162948at33208
OrthoFinder	1	1.000	-	-		FOG0000895
OrthoInspector	1	1.000	-	-		otm25575
orthoMCL	1	0.900	-	-		OOG6_100394
Panther	1	1.100	-	-	O	PTHR24058
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X888
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	10	9.780