Protein Alignment Dyrk3 and dyrk3

DIOPT Version :10

• Sequence 1: NP_001033810.1
• Gene: Dyrk3 / 3885567
• FlyBaseID: FBgn0027101
• Length: 828
• Species: Drosophila melanogaster
• Sequence 2: NP_001108400.2
• Gene: dyrk3 / 100141364
• ZFINID: ZDB-GENE-080219-31
• Length: 582
• Species: Danio rerio
• Alignment Length: 629
• Identity: 300/629 - (47%)
• Similarity: 384/629 - (61%)
• Gaps: 97/629 - (15%)

  Fly    25 LNTTHLENTQLSKALSPPTSLPQIQIQMINQNLTHTGIAQNNTEKANRHQYRDSGLQYLTRCFEP 89
            :.|.|:.|.........|:.||.:.        .|||:.:...:.   ||....|...:...:
Zfish    26 MRTDHIVNQDADVNGQSPSGLPPLP--------KHTGVIKPTMKD---HQAIRGGQMKVKYVY-- 77

  Fly    90 LAMLNDSKEDFPTQPSNNIANYPGDIQILPIFDCCEISESIQAISLPNVTSPSKTKDVPGLFLRT 154
                    ||...:..|.::.:.|..|:                  |....|:.:|:      |:
Zfish    78 --------EDSYNRKLNGVSQHNGTSQV------------------PAKPPPAISKE------RS 110

  Fly   155 ISENSKSKSEPECESLISVKESSVMENHTFLFHEQIIMSGQQKCELHEKPKVLVVSPQQVMILYM 219
            :..||..||          .|||.          ::...|..            ::|:|.:..:.
Zfish   111 VDSNSSVKS----------SESST----------KVTKLGSP------------MTPEQALKQHR 143

  Fly   220 NKLTPYERTEILTYPQIYFIGANAKKRPGVY-GPNNSEYDNEQGAYIHVPHDHVAYRYEMLKIIG 283
            .::|..|:.||..|.:|||:|.|||||..|. |.|||.||::||.||||||||:|||||.||:||
Zfish   144 QQMTTLEQQEIHNYSEIYFLGPNAKKRQAVAGGTNNSGYDDDQGGYIHVPHDHLAYRYEFLKVIG 208

  Fly   284 KGSFGQVIKAYDHKTHEHVALKIVRNEKRFHRQAQEEIRILHHLRRHDKYNTMNIIHMFDYFTFR 348
            |||||||.|.||||..:|||||||||||||||||.||||||.||::.||..:||::||.:.||||
Zfish   209 KGSFGQVAKVYDHKLQQHVALKIVRNEKRFHRQAAEEIRILEHLKKQDKTGSMNVVHMLENFTFR 273

  Fly   349 NHTCITFELLSINLYELIKKNGFKGFSLQLVRKFAHSLLQCLDALYKNDIIHCDMKPENVLLKQQ 413
            ||.|:||||||:|||||||:|.|:||||.||||||||:||||:||:::.|||||:||||:|||||
Zfish   274 NHICMTFELLSMNLYELIKRNKFQGFSLPLVRKFAHSILQCLEALHRHKIIHCDLKPENILLKQQ 338

  Fly   414 GRSGIKVIDFGSSCFENQRIYTYIQSRFYRAPEVILGGKYGRAIDMWSLGCILAELLSGHALFPG 478
            |||||||||||||||::||:|||||||||||||||||.:||..|||||.||||||||:|:.||||
Zfish   339 GRSGIKVIDFGSSCFDHQRVYTYIQSRFYRAPEVILGSRYGMPIDMWSFGCILAELLTGYPLFPG 403

  Fly   479 ENESDQLACIIEVLGMPNKNILASSKRSKSFFSPKGYPRYCTVRTMSDGMVVLIGGQSRRGKQRG 543
            |:|.|||||::|:||||...:|..:||:|:|.|.||:||||||.|:|:|.:||.|.:|||||.||
Zfish   404 EDEGDQLACMMELLGMPPSKLLEQAKRAKNFISSKGHPRYCTVSTLSNGTIVLNGSRSRRGKMRG 468

  Fly   544 PPCSKSLSKALDGCKDPLFLNFIRGCLEWDADKRLTPSEALKHPWLRRRLPRPPSSSSGCGGVSG 608
            .|.||....||.||:|..|::|::.||:||...|:||.:||:||||.:|||:|..     ||...
Zfish   469 APGSKEWGTALKGCEDATFIDFLKKCLDWDPSTRMTPVQALRHPWLYKRLPKPAP-----GGEKT 528

  Fly   609 LCSSR-------------NESPVTGQNRNFAAETTASSTSATSI 639
            :...|             ...||.|...| ...||....|..||
Zfish   529 VLPKRISEHSTSFPTIISKVPPVMGSTNN-KLRTTMMGDSTGSI 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dyrk3	NP_001033810.1	PKc_DYRK2_3	211..589	CDD:271126	253/378 (67%)
dyrk3	NP_001108400.2	PKc_DYRK2_3	135..514	CDD:271126	253/378 (67%)