Protein Alignment PIP4K and PIP5K1B

DIOPT Version :9

• Sequence 1: NP_001033805.1
• Gene: PIP4K / 3885565
• FlyBaseID: FBgn0039924
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_001362965.1
• Gene: PIP5K1B / 8395
• HGNCID: 8995
• Length: 540
• Species: Homo sapiens
• Alignment Length: 424
• Identity: 127/424 - (29%)
• Similarity: 188/424 - (44%)
• Gaps: 84/424 - (19%)

  Fly    22 KHQKVKLFR--ANEPILSVFMWGINHTINELSHVNIPVM-LLPDDFRAYSKIKVDNHLFNKENMP 83
            |..:.|.::  |:..|......||.:|:..|:  :.|.. :|..||.....:.:.:...|.  .|
Human    14 KQNEEKTYKKTASSAIKGAIQLGIGYTVGNLT--SKPERDVLMQDFYVVESVFLPSEGSNL--TP 74

  Fly    84 SH----FKVKEYCPLVFRNLRERFGVDDVDYRESLTRSQPIQIDSSGKSGAQFYQSYDKFFIIKS 144
            :|    |:.|.|.||.||..||.||:...||..|:.....|::.:.|.||:.|:.:.|..||||:
Human    75 AHHYPDFRFKTYAPLAFRYFRELFGIKPDDYLYSICSEPLIELSNPGASGSLFFVTSDDEFIIKT 139

  Fly   145 LTSEEIERMHAFLKQYHPYVVERHGKTLLPQYLGMYRITVESVQYYFVVMRNVFSSHLTIHKKFD 209
            :..:|.|.:...|..|: ..:.::.:||||::.|:|.:....:....|||.||....:.:|..:|
Human   140 VQHKEAEFLQKLLPGYY-MNLNQNPRTLLPKFYGLYCMQSGGINIRIVVMNNVLPRSMRMHFTYD 203

  Fly   210 LKGSTVDREASEKELEKNLPTFKDNDFIKQKVK-LDIGKEAKDKLMDTLSNDVDLLTKLHIMDYS 273
            |||||..|.||.||.||:.|||||.||::...: |....|..:.||.||..|..:|....|||||
Human   204 LKGSTYKRRASRKEREKSNPTFKDLDFLQDMHEGLYFDTETYNALMKTLQRDCRVLESFKIMDYS 268

  Fly   274 LLVGV----HDCVRAEEEALQ----------------------------GDNILTVGRSENSESE 306
            ||:|:    |.....|||..|                            ||.|:|    ||
Human   269 LLLGIHFLDHSLKEKEEETPQNVPDAKRTGMQKVLYSTAMESIQGPGKSGDGIIT----EN---- 325

  Fly   307 ECDSGERWTYNTPPDSPRGAQYKEVVYEVDIYDIPSIEEKRE--IYFIAIIDVLTQYGVKKQAAK 369
                         ||:..|              ||:...:.|  :.|:.|||:|..|.:.|:...
Human   326 -------------PDTMGG--------------IPAKSHRGEKLLLFMGIIDILQSYRLMKKLEH 363

  Fly   370 AAKTVKYGSNVDGISTCDPEQYAKRFLDFMDKAI 403
            :.|.:.|..  |.:|...|..||.|||.||:..:
Human   364 SWKALVYDG--DTVSVHRPSFYADRFLKFMNSRV 395

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIP4K	NP_001033805.1	PIPKc	32..403	CDD:295374	124/410 (30%)
PIP5K1B	NP_001362965.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21		2/6 (33%)
		PIPKc_PIP5K1B	27..400	CDD:340444	124/411 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5253
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52363
OrthoDB	1	1.010	-	-		D1562683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.830