Protein Alignment PIP4K and pip4k2aa

DIOPT Version :9

• Sequence 1: NP_001033805.1
• Gene: PIP4K / 3885565
• FlyBaseID: FBgn0039924
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_001122174.1
• Gene: pip4k2aa / 560360
• ZFINID: ZDB-GENE-080721-18
• Length: 404
• Species: Danio rerio
• Alignment Length: 404
• Identity: 224/404 - (55%)
• Similarity: 293/404 - (72%)
• Gaps: 21/404 - (5%)

  Fly     5 ISSSSQPRILKKKHFRVKHQKVKLFRANEPILSVFMWGINHTINELSHVNIPVMLLPDDFRAYSK 69
            :||.:.....|||||..  ||||||||::|:|||.||||||:|||||||.||:||:||||:||||
Zfish     8 VSSFASKTKTKKKHFVA--QKVKLFRASDPLLSVLMWGINHSINELSHVQIPIMLMPDDFKAYSK 70

  Fly    70 IKVDNHLFNKENMPSHFKVKEYCPLVFRNLRERFGVDDVDYRESLTRSQPIQIDSSGKSGAQFYQ 134
            ||||||||||||||||||.|||||||||||||||.:||.|::.|||||.|:..::.|:|||:|:.
Zfish    71 IKVDNHLFNKENMPSHFKFKEYCPLVFRNLRERFVIDDQDFQNSLTRSAPLVSEAQGRSGARFHT 135

  Fly   135 SYDKFFIIKSLTSEEIERMHAFLKQYHPYVVERHGKTLLPQYLGMYRITVESVQYYFVVMRNVFS 199
            ||||.::||:::||::..||..||:||.|:||.||.|||||:|||||:||:..:.|.:|.|||||
Zfish   136 SYDKRYVIKTISSEDVAEMHNILKKYHQYIVECHGSTLLPQFLGMYRLTVDGDETYMIVTRNVFS 200

  Fly   200 SHLTIHKKFDLKGSTVDREASEKELEKNLPTFKDNDFIKQKVKLDIGKEAKDKLMDTLSNDVDLL 264
            ..|:::||:|||||||.||||:||..|.|||:||||||....|:.|..|:|...::.|..||:.|
Zfish   201 HRLSVYKKYDLKGSTVAREASDKEKAKELPTYKDNDFINDGQKIYIDDESKKIFLNKLQKDVEFL 265

  Fly   265 TKLHIMDYSLLVGVHDCVRAEEEALQGDNILTVGRSENSESEECDSGERWTYNTPPDSP------ 323
            ..|.:||||||||:||..|||:|.::         ||::|.||....:.....||||||
Zfish   266 ALLKLMDYSLLVGIHDVERAEQEEVE---------SEDNEGEEEGESDGGIVGTPPDSPSNTLDS 321

  Fly   324 -RGAQYKEVVYEVDIYDIPSIEE--KREIYFIAIIDVLTQYGVKKQAAKAAKTVKYGSNVDGIST 385
             :.....:....:|:|.|.|.:.  ::|:||:|:||:|..|..||:||.||||||:|:..: |||
Zfish   322 TKPLSPGDFDPNIDVYAIKSHDNSPRKEVYFMAVIDILQHYDAKKKAAHAAKTVKHGAGAE-IST 385

  Fly   386 CDPEQYAKRFLDFM 399
            .:||||:|||.||:
Zfish   386 VNPEQYSKRFYDFI 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIP4K	NP_001033805.1	PIPKc	32..403	CDD:295374	209/377 (55%)
pip4k2aa	NP_001122174.1	PIPKc	61..403	CDD:214623	188/349 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595450
Domainoid	1	1.000	181	1.000	Domainoid score	I3421
eggNOG	1	0.900	-	-		E1_COG5253
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	431	1.000	Inparanoid score	I1688
OMA	1	1.010	-	-		QHG52363
OrthoDB	1	1.010	-	-		D1562683at2759
OrthoFinder	1	1.000	-	-		FOG0001219
OrthoInspector	1	1.000	-	-		otm25941
orthoMCL	1	0.900	-	-		OOG6_104901
Panther	1	1.100	-	-	O	PTHR23086
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2198
SonicParanoid	1	1.000	-	-		X950
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.800