Protein Alignment PIP4K and pip4k2ab

DIOPT Version :10

• Sequence 1: NP_001033805.1
• Gene: PIP4K / 3885565
• FlyBaseID: FBgn0039924
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: XP_005163424.1
• Gene: pip4k2ab / 555920
• ZFINID: ZDB-GENE-070912-272
• Length: 445
• Species: Danio rerio
• Alignment Length: 436
• Identity: 222/436 - (50%)
• Similarity: 284/436 - (65%)
• Gaps: 69/436 - (15%)

  Fly    15 KKKHFRVKHQKVKLFRANEPILSVFMWGINHTINELSHVNIPVMLLPDDFRAYSKIKVDNHLFNK 79
            ||:||  ..||||||||::|:|||.|||:||:||||.|:.|||||:||||:|.||||||||||||
Zfish    23 KKQHF--VSQKVKLFRASDPLLSVLMWGVNHSINELRHIQIPVMLMPDDFKANSKIKVDNHLFNK 85

  Fly    80 ENMPSHFKVKEYCPLVFRNLRERFGVDDVDYRESLTRSQPIQIDSSGKSGAQFYQSYDKFFIIKS 144
            ||||||||.|||||||||||||||.:||.:|:.||||..||..|:.|:|||:|:.|::|.::||.
Zfish    86 ENMPSHFKFKEYCPLVFRNLRERFSIDDQEYQNSLTRRAPIPSDAQGRSGARFHTSHNKRYVIKI 150

  Fly   145 LTSEEIERMHAFLKQYHPYVVERHGKTLLPQYLGMYRITVESVQYYFVVMRNVFSSHLTIHKKFD 209
            :|||::..||..||:||.|:||.||.|||||:|||||:||:..:.|.:|.|||||..|.::||:|
Zfish   151 ITSEDVAEMHNILKKYHQYIVECHGNTLLPQFLGMYRLTVDGDETYMIVTRNVFSHRLPVYKKYD 215

  Fly   210 LKGSTVDREASEKEL--------------------------------EKNLPTFKDNDFIKQKVK 242
            ||||||.||||:||.                                .|.|||:||||||....|
Zfish   216 LKGSTVAREASDKEKPRPPEEAPSKSRMSQKLQTIRIATRFYCAIRHTKELPTYKDNDFINDGQK 280

  Fly   243 LDIGKEAKDKLMDTLSNDVDLLTKLHIMDYSLLVGVHDCVRAEEEALQGDNILTVGRSENSESEE 307
            :.|..|.|...::.|.|||:.|.:|.:||||||||:||..|.|:|            ....|||:
Zfish   281 ICIDDENKKMFLEKLKNDVEFLAQLKLMDYSLLVGIHDVERGEQE------------QPEEESED 333

  Fly   308 CDSGER-------WTYNTPPDSPRG----------AQYKEVVYEVDIYDIPSIEE--KREIYFIA 353
            .|:||.       ....:|||||..          .::..:   :|:|.|.|.|.  |:||||:|
Zfish   334 NDAGEEEGTESDGGATGSPPDSPSNTLDSNRPLGPGEFDPI---IDVYAIKSHENAPKKEIYFMA 395

  Fly   354 IIDVLTQYGVKKQAAKAAKTVKYGSNVDGISTCDPEQYAKRFLDFM 399
            :||:||.|..||:||.||||||:|:..: |||.:||||:|||.||:
Zfish   396 VIDILTPYDAKKKAAHAAKTVKHGAGAE-ISTVNPEQYSKRFYDFI 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIP4K	NP_001033805.1	PIPKc_PIP5KII	34..401	CDD:340442	210/417 (50%)
pip4k2ab	XP_005163424.1	PIPKc	31..442	CDD:475131	217/426 (51%)