Protein Alignment PIP4K and pikfyve

DIOPT Version :9

• Sequence 1: NP_001033805.1
• Gene: PIP4K / 3885565
• FlyBaseID: FBgn0039924
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_001362234.2
• Gene: pikfyve / 550069
• XenbaseID: XB-GENE-989454
• Length: 2104
• Species: Xenopus tropicalis
• Alignment Length: 350
• Identity: 86/350 - (24%)
• Similarity: 127/350 - (36%)
• Gaps: 113/350 - (32%)

  Fly    84 SHFKVKEYCPLV----FRNLRE-RFGVDDVDYRESLTRSQPIQIDSSGKSGAQFYQSYDKFFIIK 143
            |....|.||.:.    |..:|: ..|..:.|:..||....|.|. ..|||||.||.:.|..||:|
 Frog  1820 SDANAKFYCRIYYAGEFHRMRKVILGSSEDDFIRSLAHCVPWQA-RGGKSGAAFYATEDDRFILK 1883

  Fly   144 SLTSEEIERMHAFLKQYHPYV---VERHGKTLLPQYLGMYRITVESVQ------YYFVVMRNVFS 199
            .:...|::....|...|..|:   |:....|.|.:.||:|||..::.|      ...:||.|:|.
 Frog  1884 QMPRLEVQSFLDFAPHYFTYIINAVQMKRPTALAKILGVYRIGYKNSQNNTEKKLDLLVMENLFY 1948

  Fly   200 SHLTIHKKFDLKGSTVDREA---SEKE------LEKN-LPTFKDNDFIKQKVKLDIGKEAKDKLM 254
            .. .:.:.||||||..:|..   :.||      |::| |...:||       .|.|....|..|.
 Frog  1949 GR-KMAQVFDLKGSLRNRNVKTDTGKESCDVVLLDENLLKMVRDN-------PLYIRSHCKSVLR 2005

  Fly   255 DTLSNDVDLLTKLHIMDYSLLVGVHDCVRAEEEALQGDNILTVGRSENSESEECDSGERWTYNTP 319
            .::.:|...|:...|:|||||                     |||.:.::
 Frog  2006 ASIHSDSHFLSSHLIIDYSLL---------------------VGRDDTTD--------------- 2034

  Fly   320 PDSPRGAQYKEVVYEVDIYDIPSIEEKREIYFIAIIDVLTQYGVKKQAAKAAKTVKYGSNVDGI- 383
                      |:|                   :.|||.:..:...|:.....|:.       ||
 Frog  2035 ----------ELV-------------------VGIIDYIRTFTWDKKLEMVVKST-------GIL 2063

  Fly   384 -------STCDPEQYAKRFLDFMDK 401
                   :...||.|..||.:.|||
 Frog  2064 GGQGKMPTVVSPELYRTRFCEAMDK 2088

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIP4K	NP_001033805.1	PIPKc	32..403	CDD:295374	85/349 (24%)
pikfyve	NP_001362234.2	FYVE_PIKfyve_Fab1	160..221	CDD:277264
		DEP_PIKfyve	363..444	CDD:239895
		Fab1_TCP	624..883	CDD:239450
		PIPKc_PIKfyve	1824..2090	CDD:340437	84/345 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910