DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PIP4K and pip5k1ba

DIOPT Version :9

Sequence 1:	NP_001033805.1	Gene:	PIP4K / 3885565	FlyBaseID:	FBgn0039924	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	XP_005155628.1	Gene:	pip5k1ba / 449831	ZFINID:	ZDB-GENE-041010-81	Length:	529	Species:	Danio rerio

Alignment Length:	391	Identity:	122/391 - (31%)
Similarity:	189/391 - (48%)	Gaps:	34/391 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 HQKVKLFRANEPILSVFMWGINHTINEL-SHVNIPVMLLPDDFRAYSKIKVDNHLFNKENMPSH- 85
            |:|:    ::|.:......||.:|:..| |..:..|::  .||.....:.:.:...|.  .|:|
Zfish    29 HKKL----SSEALRGAIQLGIGYTVGNLTSKPDRDVLM--QDFYVVESVFLPSEGSNL--TPAHH 85

  Fly    86 ---FKVKEYCPLVFRNLRERFGVDDVDYRESLTRSQPIQIDSSGKSGAQFYQSYDKFFIIKSLTS 147
               |:.|.|.||.||..||.||:...||..|:.:...|::.:.|.|.:.||.:.|..||||::..
Zfish    86 YPDFRFKNYAPLAFRYFRELFGIKPDDYLYSICKEPLIELSNPGASSSWFYLTSDDEFIIKTVQH 150

  Fly   148 EEIERMHAFLKQYHPYVVERHGKTLLPQYLGMYRITVESVQYYFVVMRNVFSSHLTIHKKFDLKG 212
            :|.|.:...|..|: ..:.::.:||||::.|:|.|....:....|||.||....|.:..|:||||
Zfish   151 KEAEFLQKLLPGYY-MNLNQNPRTLLPKFYGLYCIQCGGMTIRLVVMNNVLPRSLKMDYKYDLKG 214

  Fly   213 STVDREASEKELEKNLPTFKDNDFIKQKVKLDIGKEAKDKLMDTLSNDVDLLTKLHIMDYSLLVG 277
            ||..|.||.||..|:.|||||.||.:....|....:..:.||.||..|..:|....|||||||:|
Zfish   215 STYKRRASRKERAKSSPTFKDLDFQEMHEGLYFDADTYNALMKTLQRDCRVLESFKIMDYSLLLG 279

  Fly   278 VHDCVRAEEEALQGDNILTVGRSENSESEECDSGERWTYNTPPDSPRG-AQYKEVVYEVDIYDIP 341
            :|...|......:||:     |.:.:        ::..|:|..:|.:| .:..|.|.:.|...:.
Zfish   280 IHVLDRRIRRGGRGDS-----RRQGT--------QKVLYSTARESIQGDGKAPEPVADADDETLG 331

  Fly   342 SIEEKRE----IYFIAIIDVLTQYGVKKQAAKAAKTVKYGSNVDGISTCDPEQYAKRFLDFMDKA 402
            .|..|.:    :.|:.|||:|..|...|:...:.|.:.:..  |.:|...|..||.|||.||...
Zfish   332 GIPAKHKDEKLLIFLGIIDILQSYRFIKKVEHSWKALVHDG--DTVSVHRPNFYADRFLKFMGST 394

  Fly   403 I 403
            :
Zfish   395 V 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PIP4K	NP_001033805.1	PIPKc	32..403	CDD:295374	120/380 (32%)
pip5k1ba	XP_005155628.1	PIPKc	61..395	CDD:214623	113/353 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5253
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52363
OrthoDB	1	1.010	-	-		D1562683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.830