Protein Alignment PIP4K and its3

DIOPT Version :9

• Sequence 1: NP_001033805.1
• Gene: PIP4K / 3885565
• FlyBaseID: FBgn0039924
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_594429.1
• Gene: its3 / 2542231
• PomBaseID: SPAC19G12.14
• Length: 742
• Species: Schizosaccharomyces pombe
• Alignment Length: 454
• Identity: 134/454 - (29%)
• Similarity: 219/454 - (48%)
• Gaps: 71/454 - (15%)

  Fly     5 ISSSSQPRILKKKHFRVKHQKVKLFRANEPILSVFMWGINH-----TINELSHVNIPVM------ 58
            |.|:|....:|:|...::.::.:|  .:|.:|........|     ..|.|:.:.:.|.
pombe   227 IGSASWAEAVKQKRVNMRRRREEL--DDECVLVGTRVSEGHENYVTAYNMLTGIRVGVSRCQAKM 289

  Fly    59 ---LLPDDFRAYSKIKVDNHLFNKENMPS---HFKVKEYCPLVFRNLRERFGVDDVDYRESLTRS 117
               |.|.||.|..|...|  :...|..||   .||.|:|.|.|||:||:.|.:|..||..|||..
pombe   290 DRELTPADFTARHKFTFD--ITGNELTPSAKYDFKFKDYAPWVFRHLRQLFHLDAADYLVSLTSK 352

  Fly   118 QPI-QIDSSGKSGAQFYQSYDKFFIIKSLTSEEIERMHAFLKQYHPYVVERHGKTLLPQYLGMYR 181
            ..: ::||.||||:.||.|.|..||||::...|.:.:...|..|:.: |:.:..||:.|:.|::|
pombe   353 YILSELDSPGKSGSFFYFSRDYRFIIKTIHHSEHKFLREILYDYYEH-VKNNPNTLISQFYGLHR 416

  Fly   182 ITVE-SVQYYFVVMRNVFSSHLTIHKKFDLKGSTVDREASEKE-LEKNLPTFKDNDFIKQKVKLD 244
            :.:. ..:.:||||.|:|..|..||:.|||||||:.||..|.: .:..:.|.||.::|::.:.|.
pombe   417 VKLPFGRKIHFVVMNNLFPPHRDIHQTFDLKGSTLGRELDENQPCQSPMCTMKDTNWIRRNMHLQ 481

  Fly   245 IGKEAKDKLMDTLSNDVDLLTKLHIMDYSLLVGVHDCVRAEEEALQGDNILTV------------ 297
            .|...:...:..:..|:|:|:.|.|||||||||:||..|...:.:: ::||:|
pombe   482 FGPLKRQIFLTQVKADIDMLSSLGIMDYSLLVGIHDLSRGNRDKIR-NSILSVYDPNVSQHRVPS 545

  Fly   298 --GRSENSE----------------SEECDSGERWTYNTPPDSPRGAQYKEVVYEVDIYDIPSIE 344
              |...:|.                .:.|:.       .|.|  :..:.:..::..|.....:.:
pombe   546 INGNESHSNVHVIRQVVNSTGPVSLDQSCNL-------LPTD--QFVERRNFMFYSDDGGFQATD 601

  Fly   345 EKRE----IYFIAIIDVLTQYGVKKQAAKAAKTVKYGSNVDGISTCDPEQYAKRFLDFMDKAIE 404
            |..|    |::|.|||:||:|...|:.....|.:.:..:|  ||...|.:||.||..|::.:|:
pombe   602 ENNEPGNFIFYIGIIDLLTKYSYVKRVEHLWKGINHSDSV--ISAVPPAEYASRFYKFVESSIK 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIP4K	NP_001033805.1	PIPKc	32..403	CDD:295374	127/424 (30%)
its3	NP_594429.1	MSS4	1..667	CDD:227578	134/454 (30%)
		PIPKc	294..662	CDD:214623	120/382 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5253
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR23086
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2198
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.940