Protein Alignment PIP4K and PIP5K1C

DIOPT Version :9

• Sequence 1: NP_001033805.1
• Gene: PIP4K / 3885565
• FlyBaseID: FBgn0039924
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: XP_011526147.1
• Gene: PIP5K1C / 23396
• HGNCID: 8996
• Length: 731
• Species: Homo sapiens
• Alignment Length: 375
• Identity: 121/375 - (32%)
• Similarity: 189/375 - (50%)
• Gaps: 30/375 - (8%)

  Fly    42 GINHTINELSHVNIPVMLLPDDFRAYSKIKVDNHLFNKEN---MPSH----FKVKEYCPLVFRNL 99
            ||.:|:..||......:|:.|.:      .|::..|..|.   .|:|    |:.|.|.|:.||..
Human    86 GIGYTVGHLSSKPERDVLMQDFY------VVESIFFPSEGSNLTPAHHFQDFRFKTYAPVAFRYF 144

  Fly   100 RERFGVDDVDYRESLTRSQPIQIDSSGKSGAQFYQSYDKFFIIKSLTSEEIERMHAFLKQYHPYV 164
            ||.||:...||..||.....|::.:.|.||:.||.:.|..||||::..:|.|.:...|..|: ..
Human   145 RELFGIRPDDYLYSLCNEPLIELSNPGASGSLFYVTSDDEFIIKTVMHKEAEFLQKLLPGYY-MN 208

  Fly   165 VERHGKTLLPQYLGMYRITVESVQYYFVVMRNVFSSHLTIHKKFDLKGSTVDREASEKELEKNLP 229
            :.::.:||||::.|:|.:.........|||.|:....:.:|.||||||||..|.||:||.||:.|
Human   209 LNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNNILPRVVKMHLKFDLKGSTYKRRASKKEKEKSFP 273

  Fly   230 TFKDNDFIKQKVK-LDIGKEAKDKLMDTLSNDVDLLTKLHIMDYSLLVGVHDCVRAE-EEALQGD 292
            |:||.||::...: |.:..:....|:.||..|..:|....|||||||:|||:..:.| |...||
Human   274 TYKDLDFMQDMPEGLLLDADTFSALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQHERERQAQG- 337

  Fly   293 NILTVGRSENSESEECDSGERWTYNTPPDSPRGAQYKEVVYEVD--IYDIPSIEEKRE--IYFIA 353
                   ::::..|:...|::..|:|..:|.:|...:....|.|  :..||::..:.|  :..|.
Human   338 -------AQSTSDEKRPVGQKALYSTAMESIQGGAARGEAIESDDTMGGIPAVNGRGERLLLHIG 395

  Fly   354 IIDVLTQYGVKKQAAKAAKTVKYGSNVDGISTCDPEQYAKRFLDFMDKAI 403
            |||:|..|...|:.....|.:.:..  |.:|...|..||:||..||...:
Human   396 IIDILQSYRFIKKLEHTWKALVHDG--DTVSVHRPSFYAERFFKFMSNTV 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIP4K	NP_001033805.1	PIPKc	32..403	CDD:295374	121/373 (32%)
PIP5K1C	XP_011526147.1	PIPKc	103..443	CDD:214623	116/356 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5253
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1562683at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2198
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.850