Protein Alignment PIP4K and Pip5kl1

DIOPT Version :10

• Sequence 1: NP_001033805.1
• Gene: PIP4K / 3885565
• FlyBaseID: FBgn0039924
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: XP_017172887.1
• Gene: Pip5kl1 / 227733
• MGIID: 2448520
• Length: 568
• Species: Mus musculus
• Alignment Length: 316
• Identity: 74/316 - (23%)
• Similarity: 142/316 - (44%)
• Gaps: 70/316 - (22%)

  Fly     3 KKISSSSQPRILKKKHFRVKHQKVKLFRANEPILSVFMWGINHTINELSHVNIPVMLLPDDFRAY 67
            |.|||.|:..:|  .|.|.:..:|.||..          |..|.::.::.      ::.:...|.
Mouse   269 KSISSGSRRGLL--WHLRARQSRVGLFEV----------GPGHELHRMTR------MMQEGLWAA 315

  Fly    68 SKIKVDNHLFNKENMPS---------------H---FKVKEYCPLVFRNLRERFGVDDVDYRESL 114
            :::       :|.|.|:               |   |::.......|..||:..|:.:.||:.:|
Mouse   316 TQV-------SKNNPPTGPTTQKDYLEVMTQVHEEGFELGTLAGPAFARLRKSIGLTEEDYQATL 373

  Fly   115 TRSQP-IQIDSSGKSGAQFYQSYDKFFIIKSLTSEEIERMHAFLKQYHPYVVERHGKTLLPQYLG 178
            ....| :|..|:.||.|.|:.::|:.|.:|:....|:..:.|.|.:|..: ::::..:||.:.||
Mouse   374 GPGDPYLQFFSTSKSKASFFLTHDQRFFVKTQRRHEVHVLLAHLPRYVEH-LQQYPHSLLARLLG 437

  Fly   179 MYRITV-ESVQYYFVVMRNVFSSHLTIHKKFDLKGSTVDR------EASEKELEKNLPTFKDNDF 236
            :|.:.| :..:.||::|:.:|.....|.:::|:||..:.|      |.|...|     ..||.:|
Mouse   438 VYSLRVAQGKKKYFIIMQCIFYPTSRISERYDIKGCNISRWVDPAPEGSPLVL-----VLKDLNF 497

  Fly   237 IKQKVKLDIGKEAKDKLMDTLSNDVDLLTKLHIMDYSLLV----------GVHDCV 282
              |:..:.:|.: :...:..:..|...|.:::::||||||          |:|..|
Mouse   498 --QEKTMRLGAQ-RSWFLRQMELDTAFLREVNVLDYSLLVAIQFLHEDEKGIHHSV 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIP4K	NP_001033805.1	PIPKc_PIP5KII	34..401	CDD:340442	63/285 (22%)
Pip5kl1	XP_017172887.1	PIPKc	299..>543	CDD:475131	59/265 (22%)