Protein Alignment PIP4K and Pip5k1c

DIOPT Version :10

• Sequence 1: NP_001033805.1
• Gene: PIP4K / 3885565
• FlyBaseID: FBgn0039924
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_001280575.1
• Gene: Pip5k1c / 18717
• MGIID: 1298224
• Length: 687
• Species: Mus musculus
• Alignment Length: 377
• Identity: 122/377 - (32%)
• Similarity: 189/377 - (50%)
• Gaps: 34/377 - (9%)

  Fly    42 GINHTINELSHVNIPVMLLPDDFRAYSKIKVDNHLFNKEN---MPSH----FKVKEYCPLVFRNL 99
            ||.:|:..||......:|:.|.:      .|::..|..|.   .|:|    |:.|.|.|:.||..
Mouse    86 GIGYTVGNLSSKPERDVLMQDFY------VVESIFFPSEGSNLTPAHHFQDFRFKTYAPVAFRYF 144

  Fly   100 RERFGVDDVDYRESLTRSQPIQIDSSGKSGAQFYQSYDKFFIIKSLTSEEIERMHAFLKQYHPYV 164
            ||.||:...||..||.....|::.:.|.||:.||.:.|..||||::..:|.|.:...|..|: ..
Mouse   145 RELFGIRPDDYLYSLCNEPLIELSNPGASGSVFYVTSDDEFIIKTVMHKEAEFLQKLLPGYY-MN 208

  Fly   165 VERHGKTLLPQYLGMYRITVESVQYYFVVMRNVFSSHLTIHKKFDLKGSTVDREASEKELEKNLP 229
            :.::.:||||::.|:|.:.........|||.||....:.:|.||||||||..|.||:||.||:||
Mouse   209 LNQNPRTLLPKFYGLYCVQSGGKNIRVVVMNNVLPRVVKMHLKFDLKGSTYKRRASKKEKEKSLP 273

  Fly   230 TFKDNDFIKQKVK-LDIGKEAKDKLMDTLSNDVDLLTKLHIMDYSLLVGVHDCVRAEEEALQGDN 293
            |:||.||::...: |.:..:....|:.||..|..:|....|||||||:|||:..:.|.|.
Mouse   274 TYKDLDFMQDMPEGLLLDSDTFGALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQQERER----- 333

  Fly   294 ILTVGRSENSES---EECDSGERWTYNTPPDSPRGAQYKEVVYEVD--IYDIPSIEEKRE--IYF 351
                 ::|.::|   |:....::..|:|..:|.:|...:....|.|  :..||::..:.|  :..
Mouse   334 -----QAEGAQSKADEKRPVAQKALYSTAMESIQGGAARGEAIETDDTMGGIPAVNGRGERLLLH 393

  Fly   352 IAIIDVLTQYGVKKQAAKAAKTVKYGSNVDGISTCDPEQYAKRFLDFMDKAI 403
            |.|||:|..|...|:.....|.:.:..  |.:|...|..||:||..||...:
Mouse   394 IGIIDILQSYRFIKKLEHTWKALVHDG--DTVSVHRPSFYAERFFKFMSSTV 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIP4K	NP_001033805.1	PIPKc_PIP5KII	34..401	CDD:340442	122/373 (33%)
Pip5k1c	NP_001280575.1	PIPKc_PIP5K1C	76..449	CDD:340445	122/377 (32%)