Protein Alignment PIP4K and ppk-2

DIOPT Version :9

• Sequence 1: NP_001033805.1
• Gene: PIP4K / 3885565
• FlyBaseID: FBgn0039924
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_497500.1
• Gene: ppk-2 / 175344
• WormBaseID: WBGene00004088
• Length: 401
• Species: Caenorhabditis elegans
• Alignment Length: 411
• Identity: 216/411 - (52%)
• Similarity: 287/411 - (69%)
• Gaps: 23/411 - (5%)

  Fly     5 ISSSSQPRILKKKHFRVKHQKVKLFRANEPILSVFMWGINHTINELSHVNIPVMLLPDDFRAYSK 69
            :|:..:.::|.||..::...|.|||||.||:|||||||||||:::|.||..|.:|:||||:||||
 Worm     1 MSTKKKTKVLSKKKGKILVPKWKLFRAKEPVLSVFMWGINHTVDQLLHVPPPGLLMPDDFKAYSK 65

  Fly    70 IKVDNHLFNKENMPSHFKVKEYCPLVFRNLRERFGVDDVDYRESLT--RSQPIQIDSSGK-SGAQ 131
            :|:|||.|||:.||||:|||||||.|||||||:||||:.:|..|||  ..:|..:|.|.| |..:
 Worm    66 VKIDNHNFNKDIMPSHYKVKEYCPNVFRNLREQFGVDNFEYLRSLTSYEPEPDLLDGSAKDSTPR 130

  Fly   132 FYQSYDKFFIIKSLTSEEIERMHAFLKQYHPYVVERHGKTLLPQYLGMYRITVESVQYYFVVMRN 196
            |:.||||.|:|||:.||.:..:|:.|:.||.||||:.||||||||||:||:|:|..:.|.:||||
 Worm   131 FFISYDKKFVIKSMDSEAVAELHSVLRNYHQYVVEKQGKTLLPQYLGLYRLTIEGSETYLIVMRN 195

  Fly   197 VFSSHLTIHKKFDLKGSTVDREASEKELEKNLPTFKDNDFIKQKVKLDIGKEAKDKLMDTLSNDV 261
            ||.....:|.|||||||||.|.||:||..|:|||.|||||::|..||::..||...|::.|::|.
 Worm   196 VFGRKYGVHTKFDLKGSTVSRAASDKEKAKDLPTLKDNDFLEQNWKLNLPPEAGKLLIEMLTSDT 260

  Fly   262 DLLTKLHIMDYSLLVGVHDCVRAEEEALQGDNILTVGRSENSESEECDSGERWTYNTPPDSP--- 323
            :.||::|:||||||||:|||.||.:||        ..|.....|||  ||:... .||||||
 Worm   261 EWLTRMHLMDYSLLVGIHDCERAAQEA--------ANRPVEQNSEE--SGDELA-PTPPDSPIPS 314

  Fly   324 RGAQYKEVVYEVDIYD------IPSIEEKREIYFIAIIDVLTQYGVKKQAAKAAKTVKYGSNVDG 382
            .|..:..|....|:.|      .|:..||..||||.::|:||.||:||::|.|||||||||:.:.
 Worm   315 TGGAFPGVSGGPDLDDEFYAIASPADFEKNLIYFIGLVDILTYYGIKKRSATAAKTVKYGSDAEN 379

  Fly   383 ISTCDPEQYAKRFLDFMDKAI 403
            |||..|||||||.::|:.:|:
 Worm   380 ISTVKPEQYAKRLVEFVSRAL 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PIP4K	NP_001033805.1	PIPKc	32..403	CDD:295374	205/382 (54%)
ppk-2	NP_497500.1	PIPKc_PIP5KII	30..398	CDD:340442	204/378 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166927
Domainoid	1	1.000	267	1.000	Domainoid score	I995
eggNOG	1	0.900	-	-		E1_COG5253
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2634
Inparanoid	1	1.050	416	1.000	Inparanoid score	I1022
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52363
OrthoDB	1	1.010	-	-		D1562683at2759
OrthoFinder	1	1.000	-	-		FOG0001219
OrthoInspector	1	1.000	-	-		oto19651
orthoMCL	1	0.900	-	-		OOG6_104901
Panther	1	1.100	-	-	LDO	PTHR23086
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2198
SonicParanoid	1	1.000	-	-		X950
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.800