Protein Alignment t-Grip84 and SPC98

DIOPT Version :10

• Sequence 1: NP_648139.1
• Gene: t-Grip84 / 38852
• FlyBaseID: FBgn0035800
• Length: 728
• Species: Drosophila melanogaster
• Sequence 2: NP_014273.1
• Gene: SPC98 / 855597
• SGDID: S000005070
• Length: 846
• Species: Saccharomyces cerevisiae
• Alignment Length: 771
• Identity: 150/771 - (19%)
• Similarity: 260/771 - (33%)
• Gaps: 246/771 - (31%)

  Fly    80 ENLAKMSLPCQEQLL--MRDLIYAFSGVPSAYVKPDIQ-IDQISEMSAVDIAKIRFRLKKTFTG- 140
            ||||.     .|.||  :|        .||.|.:...: :|:.||..::..:..|:....|::.
Yeast   114 ENLAN-----HEHLLSPVR--------APSIYTEASFENMDRFSERRSMVSSPNRYVPSSTYSSV 165

  Fly   141 AFRALANETLPLIGYYISVQSYIEETNMSPNCGRTRLTLATAL----SDQLQD------------ 189
            ..|.|:|.      ||::.   |.|.::......|.|...:||    .:|:|.
Yeast   166 TLRQLSNP------YYVNT---IPEEDILKYVSYTLLATTSALFPFDHEQIQIPSKIPNFESGLL 221

  Fly   190 ---------YYDLQSKLETDLQDKKLDL----KDLVRQVRPWLPILKTFSNMASSARGNLTSAQV 241
                     |..|..|:|   :.:.|::    |.|:.::...|.....|.|       ||.|:..
Yeast   222 HLIFEAGLLYQSLGYKVE---KFRMLNISPMKKALIIEISEELQNYTAFVN-------NLVSSGT 276

  Fly   242 LTLLDQFYRDLKDT---------------------------------DIDLKERVNKILTSTSRA 273
            :..|...||::.:.                                 |:.:::....:..|....
Yeast   277 VVSLKSLYREIYENIIRLRIYCRFTEHLEELSGDTFLIELNIFKSHGDLTIRKIATNLFNSMISL 341

  Fly   274 YMKIVQLWMQKGVLFDTQHEFFV-EDTEPSSTMSSTLLAPEKCCHAYWAERYRLLP-----DRLP 332
            |.:.:..|:.||:|..|..|||: |:|:.:.|....:              |. :|     :|:|
Yeast   342 YYEYLMNWLTKGLLRATYGEFFIAENTDTNGTDDDFI--------------YH-IPIEFNQERVP 391

  Fly   333 GFLLSQ-ADDIFLAGK-YLNILRQC---------NVSLKLLQRPLAYSQGDLGHEEIIKTSYELP 386
            .|:..: |..||:.|| |:.:.:.|         :....:|.:..:|........|||...|...
Yeast   392 AFIPKELAYKIFMIGKSYIFLEKYCKEVQWTNEFSKKYHVLYQSNSYRGISTNFFEIINDQYSEI 456

  Fly   387 AHKFLKVLVEEHNLPLHIRN----LKSYFLLQEEGFSETFLHKCHEYL--------KYNVERLIP 439
            .:...::|    |...|.|:    ||:..|:.:..|.:..:.|.::.|        .|.:.|::.
Yeast   457 VNHTNQIL----NQKFHYRDVVFALKNILLMGKSDFMDALIEKANDILATPSDSLPNYKLTRVLQ 517

  Fly   440 EKLQTLLAETLHKSNDFIKDNVRCQLKVCDVATLLGRQHKAQRAVEDEEEEEKESCSEQDPPEVL 504
            |.:|  |:...|..|                                   ..:.|       .|:
Yeast   518 EAVQ--LSSLRHLMN-----------------------------------SPRNS-------SVI 538

  Fly   505 NLYGYEALALGY-ETKW---PLSFIIYPELLEQLQMLQ--------RVLFFL--------HYVKH 549
            |......|.||: ...|   .|.:|:||.|...|.:.:        |:..||        .|.|.
Yeast   539 NGLDARVLDLGHGSVGWDVFTLDYILYPPLSLVLNVNRPFGRKEYLRIFNFLWRFKKNNYFYQKE 603

  Fly   550 HL----------TVLWQSPCEGTGLQLTNRSGKLRHRMLMCMLSLENHIIQDITEPRWQSLT--- 601
            .|          .:...:|.....:...:|...||.:.......:|::.:..|.|..::.:|
Yeast   604 MLKSNDIIRSFKKIRGYNPLIRDIINKLSRISILRTQFQQFNSKMESYYLNCIIEENFKEMTRKL 668

  Fly   602 -LTVDKAKCIDEVLNKLESTVEECLRLGLLPTANTFVKSLYTLGHVCLNFCDFVESSIGEKSTKE 665
             .|.:|::...:::.....|:|  |...|.|.|....||               .||..:|...|
Yeast   669 QRTENKSQNQFDLIRLNNGTIE--LNGILTPKAEVLTKS---------------SSSKPQKHAIE 716

  Fly   666 LEQEVVEYEEEFKSFLTSILELVSQLAKTKDIAERDSCKQ-----LLKRLGELIEF 716
            ....:.|.|....:|||:||........|.:|:..|...|     |:..|..:.||
Yeast   717 KTLNIDELESVHNTFLTNILSHKLFATNTSEISVGDYSGQPYPTSLVLLLNSVYEF 772

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
t-Grip84	NP_648139.1	GCP_N_terminal	96..397	CDD:465456	71/381 (19%)
		GCP_C_terminal	400..710	CDD:461187	68/360 (19%)
SPC98	NP_014273.1	GCP_N_terminal	185..467	CDD:465456	56/310 (18%)
		GCP_C_terminal	476..823	CDD:461187	69/358 (19%)