Protein Alignment t-Grip84 and Tubgcp2

DIOPT Version :10

• Sequence 1: NP_648139.1
• Gene: t-Grip84 / 38852
• FlyBaseID: FBgn0035800
• Length: 728
• Species: Drosophila melanogaster
• Sequence 2: NP_598516.2
• Gene: Tubgcp2 / 74237
• MGIID: 1921487
• Length: 905
• Species: Mus musculus
• Alignment Length: 755
• Identity: 198/755 - (26%)
• Similarity: 330/755 - (43%)
• Gaps: 130/755 - (17%)

  Fly    35 ESVDEKMRPSGSENSGHNCNTS----------------SSSSLPRQESWIFE--SVGGYFLANEN 81
            :.::|..:..||.::|.....|                |...||...:|::|  ::.|.||....
Mouse   132 QELEELRKQLGSVSTGSTLQQSLELTRKMLRDKQNKKNSGQPLPVFPAWVYERPTLAGDFLIGSG 196

  Fly    82 LAK--------MSLPCQEQLLMRDLIYAFSGVPSAYVKPDIQIDQISEMSAVDIAKIRFRLKKTF 138
            |:.        :.|..||..::.||:|...||...|:            :|..:|.   |..:||
Mouse   197 LSSDTVLPIGTLPLASQESAVVEDLLYVLVGVDGRYI------------TAQPLAG---RQNRTF 246

  Fly   139 TG------AFRALANETLPLIGYYISVQSYIEETNMSPNCGRTRLTLATALSDQLQDYYDLQSKL 197
            ..      :.|.|.|..||:...|.:|..:|||.: |...|:....||.|:...:::|..|.::|
Mouse   247 LVDPNLDLSIRELVNRILPVAASYSTVTRFIEEKS-SFEYGQVNHALAAAMRTLVKEYLILVTQL 310

  Fly   198 ETDLQDKKLDLKDLVRQVRPWLPILKTFSNMASSA-RGNLTSAQVLTLLDQFYRDLKDT-DIDLK 260
            |...:...|.|:.|...::|.:..:...:::|:|. :|.......|:||..  |....| |...:
Mouse   311 EQLHRQGLLSLQKLWFYIQPAMRTIDILASLATSVDKGECVGGSTLSLLHD--RSFNYTGDSQAQ 373

  Fly   261 ERVNKILTSTSRAYMKIVQLWMQKGVLFDTQHEFFVEDTEPSSTMSSTLLAPEKCCH----AYWA 321
            |....:..:.|..|.:|::.|:.:|::.|...||.||:.|         |..||...    .||.
Mouse   374 ELCLYLTKAASAPYFEILEKWIYRGIIHDPYSEFMVEEHE---------LRKEKIQEDYNDKYWD 429

  Fly   322 ERYRLLPDRLPGFLLSQADDIFLAGKYLNILRQCNVSLKL-LQRPLAYSQGDLGHEEIIKTSYEL 385
            :||.:||.::|.||...|..|...|||||::|:|...:.. :.:.:.|:..:..:.|.|:.::..
Mouse   430 QRYTVLPQQIPSFLQKVAGKILSTGKYLNVVRECGHDVTCPVAKEIIYTLKERAYVEQIEKAFNY 494

  Fly   386 PAHKFLKVLVEEHNLPLHIRNLKSYFLLQEEGFSETFLHKCHEYLKYNVERLIPEKLQTLLAETL 450
            .:...|..|:||..|..|:|::|.|||:.:..|...|:....|.|:..||.:|..:|:.||...|
Mouse   495 ASKVLLDFLMEEKELVAHLRSIKRYFLMDQGDFFVHFMDLTEEELRKPVEDIILTRLEALLELAL 559

  Fly   451 HKS---NDFIKDNVRCQLKVCDVATLLGRQHKAQRAVEDEEEEEKESCSEQDPPEVLNLYGYEAL 512
            ..|   .|..||:::.:|...|:.|.|.|    ..|:|.::|   ::.:..||.| |.|.|.||.
Mouse   560 RMSTANTDPFKDDLKIELMPHDLITQLLR----VLAIETKQE---KAMTHADPTE-LTLSGLEAF 616

  Fly   513 ALGYETKWPLSFIIYPELLEQLQMLQRVLFFLHYVKHHLTVLWQSPCEGTGLQLTNRSGK----- 572
            :..|..|||||.||..:.|.:.|||.|.:|:..:|:..|..:|.|  ..|..|....|.|
Mouse   617 SFDYMVKWPLSLIINRKALTRYQMLFRHMFYCKHVERQLCSVWIS--NKTAKQHALHSAKWFAGA 679

  Fly   573 --LRHRMLMCMLSLENHIIQDITEPRWQSLTLTVDKAKCIDEVLNKLESTVEECLRLGLLPTANT 635
              ||.|||..:.:::.:::.::.||.|..|...:..|..||:||....|.::.||:..:| |...
Mouse   680 FTLRQRMLNFVQNIQYYMMFEVMEPTWHILEKNLKSASNIDDVLGHHTSFLDNCLKDCML-TNPE 743

  Fly   636 FVKSLYTLGHVCLNFCDFVESSIGEKSTKELEQEVVEYEEEFKSFLTSILELVSQLAK------- 693
            .:|....|..||:.|.:.::.                        .|..::|.|:|.:
Mouse   744 LLKVFSKLMSVCVMFTNCMQK------------------------FTQSMKLDSELGRLTLDQGS 784

  Fly   694 -------TKDIAERDSCKQLLKRLGELIEFSDLDKDQIAS 726
                   |:.|.:|...:...|.|.|     .:|..|:||
Mouse   785 VQGPPTETERIEDRPRKELTRKHLSE-----HVDAPQLAS 819

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
t-Grip84	NP_648139.1	GCP_N_terminal	96..397	CDD:465456	81/313 (26%)
		GCP_C_terminal	400..710	CDD:461187	92/333 (28%)
Tubgcp2	NP_598516.2	GCP_N_terminal	218..506	CDD:465456	81/314 (26%)
		GCP_C_terminal	509..868	CDD:461187	98/351 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	877..905