Protein Alignment t-Grip84 and Grip91

DIOPT Version :10

• Sequence 1: NP_648139.1
• Gene: t-Grip84 / 38852
• FlyBaseID: FBgn0035800
• Length: 728
• Species: Drosophila melanogaster
• Sequence 2: NP_524919.2
• Gene: Grip91 / 48481
• FlyBaseID: FBgn0001612
• Length: 917
• Species: Drosophila melanogaster
• Alignment Length: 756
• Identity: 147/756 - (19%)
• Similarity: 272/756 - (35%)
• Gaps: 204/756 - (26%)

  Fly    49 SGHNCNTSSSSSLPRQESWIFESVGGYFLANENLAKMSLPCQEQLLMRDLIYAFSGVPSAYVKPD 113
            :.|:.:.:.||...|::|          |.|...|...||.....::...||:|:||...|:|.|
  Fly   197 ASHSYDATQSSIGLRKQS----------LPNYLDATKMLPESRHDIVMSAIYSFTGVQGKYLKKD 251

  Fly   114 IQIDQISEMSAVDIAKIRFRLKKTFTGAFRALANETLPLIGYYISVQSYIEETNMSPNC-GRTRL 177
            :    ::....:|...|:|    ..||....|..  |..:|||........:.:...|. |....
  Fly   252 V----VTGRFKLDQQNIKF----LTTGQAGMLLR--LSELGYYHDRVVKFSDVSTGFNAIGSMGQ 306

  Fly   178 TLATALSDQLQDYYDLQSKLETDLQ-----------------------DKKLDLKDLVRQVRP-- 217
            .|.:.|.::|.:::...:.|..::|                       |:....|.|...::|
  Fly   307 ALISKLKEELANFHGQVAMLHDEMQRFRQASVNGIANKGKKDSGPDAGDEMTLFKLLAWYIKPLH 371

  Fly   218 ---WLPILKTFSNMASSAR----GNLTSAQVLTLLDQFYRDLKDTDIDLKER-VNKILTSTSRAY 274
               ||      :.:|.:.:    |:|.|.         ..|..|...|:..: |..:||:.....
  Fly   372 RMQWL------TKIADACQVKKGGDLAST---------VYDFLDNGNDMVNKLVEDLLTAICGPL 421

  Fly   275 MKIVQLWMQKGVLFDTQHEFFVEDTEPSSTMSSTLLAPEKCCHAYWAERYRLLPDRLPGFL-LSQ 338
            ::::..|:.:|.:.|...||||:..:....            ...|.:::||....||.|: :..
  Fly   422 VRMISKWILEGGISDMHREFFVKSIKDVGV------------DRLWHDKFRLRLPMLPKFVPMDM 474

  Fly   339 ADDIFLAGKYLNILRQ-CNVSLKLLQRP-------------LAYSQGDLGHEEIIKTSYELPAHK 389
            |:.|.:.||.:|.||: |.....:.:|.             .:|:. |......::|.|:..:..
  Fly   475 ANKILMTGKSINFLREICEEQGMMKERDELMKVMESSASQIFSYTP-DTSWHAAVETCYQQTSKH 538

  Fly   390 FLKVLVEEHNLPLHIRNLKSYFLLQEEGFSETFLHKCHEYLKYNVER----LIPEKLQTLLAETL 450
            .|.::|..|.|..|:..::.|.||.:..|....:    |.:|..:||    :....|.::|...|
  Fly   539 VLDIMVGPHKLLDHLHGMRRYLLLGQGDFISILI----ENMKNELERPGLDIYANDLTSMLDSAL 599

  Fly   451 HKSNDFIKDNVRCQLKVCDVATLLGRQHKAQRAVEDEEEEEKESCSEQDPPEVLNL--------- 506
            ..:|                                         ::.|.|::||.
  Fly   600 RCTN-----------------------------------------AQYDDPDILNHLDVIVQRPF 623

  Fly   507 ---YGYEALALGYETKWPLSFIIYPELLEQLQMLQRVLFF-LHYVKHHLTVL----WQSPCEGTG 563
               .|:..::|.|....||:     .:||......:|||. |..:||...||    |:.......
  Fly   624 NGDIGWNIISLQYIVHGPLA-----AMLESTMPTYKVLFKPLWRMKHMEFVLSMKIWKEQMGNAK 683

  Fly   564 LQLTNRS--GKLRHRM------LMCML-SLENHIIQDITEPRWQSLTLTVDKAKCIDEVLNKLES 619
            ...|.:|  ||..||:      :|..: .::.:::.::.|..|..|...:.||..:||:|...|.
  Fly   684 ALRTMKSEIGKASHRLNLFTSEIMHFIHQMQYYVLFEVIECNWVELQKKMQKATTLDEILEAHEK 748

  Fly   620 TVEECLRLGLLPTANTFVKSLYTLGHVCLNFCDFVESSIGEKSTKELEQEVVEYEEEFKSFLTSI 684
            .::..|       ...||.:..::.|                |.:.:.:.::|.|:...||....
  Fly   749 FLQTIL-------VGCFVSNKASVEH----------------SLEVVYENIIELEKWQSSFYKDC 790

  Fly   685 LELVSQLAKTKDIAERDSCKQLLKRLGELIEFSDLDKDQIA 725
            .:.::...:...|.|:...|.:.....::|    |.:||.|
  Fly   791 FKELNARKELSKIVEKSEKKGVYGLTNKMI----LQRDQEA 827

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
t-Grip84	NP_648139.1	GCP_N_terminal	96..397	CDD:465456	69/349 (20%)
		GCP_C_terminal	400..710	CDD:461187	62/339 (18%)
Grip91	NP_524919.2	GCP_N_terminal	230..544	CDD:465456	68/351 (19%)
		GCP_C_terminal	549..880	CDD:461187	67/356 (19%)