Protein Alignment t-Grip84 and Grip163

DIOPT Version :10

• Sequence 1: NP_648139.1
• Gene: t-Grip84 / 38852
• FlyBaseID: FBgn0035800
• Length: 728
• Species: Drosophila melanogaster
• Sequence 2: NP_648537.2
• Gene: Grip163 / 39365
• FlyBaseID: FBgn0026432
• Length: 1351
• Species: Drosophila melanogaster
• Alignment Length: 835
• Identity: 163/835 - (19%)
• Similarity: 284/835 - (34%)
• Gaps: 288/835 - (34%)

  Fly     4 DKSESDFANKVRFHLSKDELERQMRKIHDREESVDEKM-------------RPSGSENSGHNC-- 53
            :|...|..|::.|   :.|.||...|:.:||:...:|.             |.:.|:.|..:|
  Fly   622 EKRRQDIVNELAF---QRECERMEDKLLEREKQELQKKVVQLAAVLSSSPDRSTVSDLSFASCIE 683

  Fly    54 ------NTSSSSSLPRQESWIFESVGGYFLANENLAK-MSLPCQEQLLMRDLIYAFSGVPSAYVK 111
                  .:||.......|:...|       |.:.|.| :::|.::              |.|..:
  Fly   684 EPDCLAESSSDKDDANTENSEDE-------ATKQLDKTLNVPLEQ--------------PEAEYQ 727

  Fly   112 PDIQIDQISEMSAVDIAKIRFRLKKTFTGAFRALANETLPLIGYYISVQSYIEETNMSPNC---- 172
            .|:.:||.             |.|:.           :||.:..|....|.:..:|..|..
  Fly   728 ADVDVDQP-------------RGKEC-----------SLPNVFQYQRSHSDVINSNEHPTTQAEF 768

  Fly   173 GRTR---LTLATALSDQLQDYYDLQSKLETDLQDKKLDLKDLVRQVRPWLPILKTFSNMAS---- 230
            .|.|   |:     |||.|..:......|:||                    |||.::.:|
  Fly   769 NRNRQHGLS-----SDQFQQCHATVHLQESDL--------------------LKTAASTSSGLHA 808

  Fly   231 ------SARGNLTSAQVLTLL----------DQFYRDLKDTDIDLKERVNKILTSTS---RAYMK 276
                  :|..|....:.||.|          |.|: ....|:.:...|:..:|.|.:   |..::
  Fly   809 EIPQDINANLNCPDTKELTELQRNRKRNEHHDGFF-SFNSTEDEHTHRLRSLLNSNTERGRNRLR 872

  Fly   277 IVQLWMQKG---------------VLFDTQH-----------------EF---------FVEDTE 300
            :::.....|               :..|..|                 :|         .:.||.
  Fly   873 VMETEFGLGYKNTDIETKATPCLPLEIDKLHVEIPLAVLTPMSTTSDVDFGDPSPRELPEIADTA 937

  Fly   301 PSSTMSSTL--LAPE--KCCHAYWAERYRLLP--------------DRLPGFLLSQADDIFLAGK 347
            .::.:|.::  |:||  |...|. |:...|||              ||.....|.:|.:.|:|
  Fly   938 NNNNVSGSIESLSPELPKPVLAI-AKPTSLLPKLDFGMKDERETEQDRDKVSTLPEACNPFMA-- 999

  Fly   348 YLNILRQCNVSLKLLQRPLAYSQGDLGHEEIIKTSYELPAHKFLKVLVEEHNLPLHIRNLKSYFL 412
                 |:| :.|.::....||              |.|..::.|::. :|..:..|.|.|::||.
  Fly  1000 -----RRC-LQLSVMAPLNAY--------------YGLLRNEVLRIF-QEQRIYEHFRKLRNYFF 1043

  Fly   413 LQEEGFSETFLHKCHEYLKYNV-ERLIPEK--LQTLLAETLHKSNDFIKDNVRCQLKVCDVATLL 474
            |.:..|..|..::....::..| .|.:.:|  |.|:|...|
  Fly  1044 LVDGQFGATLTNEILGRIRAGVGPRSLSQKGILDTILTNAL------------------------ 1084

  Fly   475 GRQHKAQRAVEDEEEEEKESCSEQDPPEVLNLYGYEA---LALGYETKWPLSFIIYPELLEQLQM 536
                 |..:.::....|..:.:....|:.||....||   |.|..:..|||:.:|..|.:.:...
  Fly  1085 -----AACSADETTVSENLTLNCTTIPDTLNFLSVEATSMLKLNCKIDWPLNMVISSETISKYGQ 1144

  Fly   537 LQRVLFFLHYVKHHLTVLWQSPCEGTGLQLTNRSGKL-----------------RHRMLMCMLSL 584
            :...|..|.:|...|        :|| .:...:.|||                 ||:|...|.|.
  Fly  1145 IFGYLLKLRHVSFVL--------DGT-YEYLQQMGKLLGPELRTCTHFRHMQMMRHKMSHFMTSF 1200

  Fly   585 ENHIIQDITEPRWQSLTLTVDKAKCIDEVLNKLESTVEECLRLGLLPTANTFVKSLYTLGH---V 646
            :.|::.......|:|....:..|..|:.:..:..:.::....|.||...:..||.  |:.:   :
  Fly  1201 QTHLVAKALLSTWKSFKEELCTADSIEALYKQHVAYLKRVAFLALLNRRSAKVKE--TIDNILVI 1263

  Fly   647 CLNFCDFVESS--IGEKST-------KELEQEVVEYEEEFKSFLTSILELVSQLA 692
            .|.||..::|.  |.::..       |.|:||    |.||:.||..::.|.::.|
  Fly  1264 ILRFCKVIQSQSFIVDQDNYFVHPRFKRLQQE----EAEFEKFLQYLIYLGNKAA 1314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
t-Grip84	NP_648139.1	GCP_N_terminal	96..397	CDD:465456	69/389 (18%)
		GCP_C_terminal	400..710	CDD:461187	70/328 (21%)
Grip163	NP_648537.2	GCP_N_terminal	273..523	CDD:465456
		EnvC	<532..>677	CDD:443969	13/57 (23%)
		GCP_C_terminal	1033..1335	CDD:461187	70/326 (21%)