Protein Alignment t-Grip84 and Grip75

DIOPT Version :10

• Sequence 1: NP_648139.1
• Gene: t-Grip84 / 38852
• FlyBaseID: FBgn0035800
• Length: 728
• Species: Drosophila melanogaster
• Sequence 2: NP_609412.1
• Gene: Grip75 / 34441
• FlyBaseID: FBgn0026431
• Length: 650
• Species: Drosophila melanogaster
• Alignment Length: 701
• Identity: 146/701 - (20%)
• Similarity: 267/701 - (38%)
• Gaps: 176/701 - (25%)

  Fly    88 PCQEQLLMRDLIYAFSGVPSAYVKPDIQIDQISEMSAVDIAKIRFRLKKTFTGAFRALANETLP- 151
            ||:.::.| |:|        ..:|...:::|.:..|.          :|:.|       :..||
  Fly    34 PCEREIFM-DII--------KIIKVYQEVEQFTHSSG----------RKSDT-------HGELPD 72

  Fly   152 -LIGYYISVQSYIEETNMSPNCGRTRLTLATALSDQLQDYYDLQSKLET-DLQDKKLDLKDLVRQ 214
             |.|||:                   |.||..:...|::||....:||. .|.:::..|..:...
  Fly    73 SLHGYYL-------------------LNLAKGIEMALEEYYAEIGRLEKYCLGNERNSLSYVYNA 118

  Fly   215 VRPWLPILKTFSNMASSARGNLTSAQVL-----TLLDQFYRDLKDTDIDLKERVNKILTSTSRAY 274
            :....|:|....|:       :|...||     .||...::..:..||.|::.:..|:.....|:
  Fly   119 LYAKFPLLVFMRNL-------ITEIHVLNLRGCVLLHNLHQQCEHGDIQLEKAIKIIMKPVKNAF 176

  Fly   275 MKIVQLWMQKGVLFDTQHEFFVEDTEP--------SSTMSSTLLAPEKCCHAY-WAERYRLLPDR 330
            ...:..|:..||:.|...|||::.|..        |.:.:.:||:.||....| |  :|.:...:
  Fly   177 FSSLAHWLLFGVIDDVHSEFFIKFTPTDAVDGSSFSKSATCSLLSAEKNPEDYIW--QYEVNMSQ 239

  Fly   331 LPGFL-LSQADDIFLAGKYLNILRQ-CNVSLKLLQRPLAYSQGDLGHEEIIKTSYEL---PAHKF 390
            ||||. :..|:.:...|:.:.:.:. .||.:|....|||....:|..::|    |:|   ...:|
  Fly   240 LPGFFSIVLAEKVLFVGQTVLVFKMGRNVKVKNKTDPLAAKLAELDSDDI----YQLWSGRESEF 300

  Fly   391 LKVLVEEHN-----------LPLHIRN----------------------LKSYFLLQEEGFSETF 422
            .|::|:..|           :.:.|:|                      :|.:|||   |..|.:
  Fly   301 FKMVVDLSNEDTINVFRLEKVIIDIKNYVSARLSEIAVNEVDLERQMGLIKDFFLL---GRGEFY 362

  Fly   423 LHKCHEYL----KYNVERLIPEKLQTLLAETLHK-SNDFIKDNVRCQLKVCDVATLLGRQHKAQR 482
            |..|.:.:    .|..||.........||.|:.. ::|..|.::.||
  Fly   363 LEFCSQMVGTMETYREERFKNVTRSFELAATVTGITDDLDKFSLICQ------------------ 409

  Fly   483 AVEDEEEEEKESCSEQDPPEVLNLYGYEALALGYETKWPLSFIIYPELLEQLQMLQRVLFFLHYV 547
                      .|.||.|.....|.  .:.|:|.||.:|||:.:..|..:|:...:.|.|..:...
  Fly   410 ----------RSTSEPDDTSDFNF--LQGLSLKYEYEWPLNLLFSPTTIERYNNIFRFLLIIRTY 462

  Fly   548 KHHLTVLWQSPC----EGTGLQLTNRSGKLRHRMLMCMLSLENHIIQDITEPRWQSLTLTVDKAK 608
            ::.:..:|....    ....:...|:...||:.::..:.:::.:|..|:.|.:: .:.:.|.|::
  Fly   463 QYEIQRVWAKQTWRAKSAKDVPPNNKIITLRNYLMFFLNNMQYYIQVDVLESQF-GILMNVIKSR 526

  Fly   609 CIDEVLNK-----LESTVEECLRLGLLPT---------ANTFVKSLYTLGHVCLNFCDFVESSIG 659
            ...||:.:     |.:.:..|..|....|         .|....:|..|..:|..|....::
  Fly   527 SDFEVIQRAHTVFLANVLSHCFLLNESETQLNVTGSQNRNPIYGTLLKLFGICEKFAHMTQT--- 588

  Fly   660 EKSTKELEQEVVEYEEEFKSFLTSILELVSQLAKTKDIAERDSCKQLLKRL 710
            :..:.:||.||.:..|.|...:.|:::|   |...|..:......|||.||
  Fly   589 KDPSDDLEDEVDQLNESFGVQIASLIQL---LVDVKSASCLGPLSQLLLRL 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
t-Grip84	NP_648139.1	GCP_N_terminal	96..397	CDD:465456	71/322 (22%)
		GCP_C_terminal	400..710	CDD:461187	69/354 (19%)
Grip75	NP_609412.1	GCP_N_terminal	2..340	CDD:465456	77/363 (21%)
		GCP_C_terminal	349..642	CDD:461187	69/328 (21%)