Protein Alignment mmm and dync1i1b

DIOPT Version :10

• Sequence 1: NP_648138.1
• Gene: mmm / 38851
• FlyBaseID: FBgn0035799
• Length: 1132
• Species: Drosophila melanogaster
• Sequence 2: XP_005158174.1
• Gene: dync1i1b / 561525
• ZFINID: ZDB-GENE-061215-62
• Length: 645
• Species: Danio rerio
• Alignment Length: 758
• Identity: 128/758 - (16%)
• Similarity: 247/758 - (32%)
• Gaps: 245/758 - (32%)

  Fly   183 ERWRMQRRLRKKPRRWVSHGTDEEMTIMVERFKDEPIDVEIQSVYPIQMPRHVAFDYRMTRDVRD 247
            :|..::..|.:|.:| ::...:|:.....||.|.|.   |:     :|.|.:|..|..:.|..|:
Zfish     3 DRSDLKAELERKKQR-LAQIREEKKRKEEERKKKES---EM-----LQRPENVTEDSDLDRKRRE 58

  Fly   248 --------GV---------LELLPNENIKWENVTKKRVNVSVQSAPPKIEREQQTN--------- 286
                    |:         |:||..:...:..:....::.|.||..|..|...|.:
Zfish    59 TEALLQSIGISPEPPLVQPLQLLTWDTCYFHYLVPTPMSPSSQSVSPPSETGSQESIDGGTVERT 123

  Fly   287 ---PTFPS---------------NAWSQYLYEIDDEDLEL-------------DETDVDEEEEKK 320
               .|.||               ...:..:.:||....||             ::.:.:::||..
Zfish   124 LQWDTDPSALQLLADSVHGCRMQRLGASKIVQIDFMPKELVTYSKETQTPVASNQPEEEDDEELS 188

  Fly   321 KAQAKPGTYVEPEKKPPEMSAQIEMLLNTLEFNQIDSYRDDYSLISSRQV--------------V 371
            ..:::|.:....|:|..|:.......|...|..|| .:.:|:.....|.:              .
Zfish   189 VPKSEPASQQLEEEKTQEVEEVHPRELTNEEKEQI-VHSEDFLFFFDRSIRVVERVLAEDKDIFF 252

  Fly   372 QYTNPYLQ----EFLCFANIS---------KSNKRFVAGYDWYPKLSGLIAVSYAFSTPATVNEA 423
            .|:...::    :....:|:|         .|..|.|...||.|:...|:..||     .|..:|
Zfish   253 DYSGRDMEDKEGDLQAGSNLSFNRHFYDEHWSKHRVVTSLDWSPQYPELLVASY-----NTNEDA 312

  Fly   424 TNRVDYVQRAVLEPNPVLLWSFSDNLNYKLE-----FEAPIETTALTFCPFNGDILLGGSKNGQV 483
            .:..|.|         ||:|    |:.:|..     |.......::.|..|:.::::||:.:||:
Zfish   313 PHEPDGV---------VLVW----NMKFKKATPEYIFHCQSSVMSVGFAQFHPNLVIGGTYSGQI 364

  Fly   484 VLWDLQGRCEKLDEEEYLTAAQAKYRIMIGEFLNWTIDIEDNVIVPATISLLDCSPKGAITAFYW 548
            .:||.:.......:...|:|....:.:..           .||:.....:.|
Zfish   365 AMWDNRSHRRTPVQRTPLSATAHTHPVYC-----------VNVVGTQNANNL------------- 405

  Fly   549 LGRSIYLSQFGKVYNDPDIRNHHKFFVTCAFDGTISFWDLDGKGGKSAKDKMRNRMLPKELTQSE 613
                                      :|.:.||.:..|.||                  .|:|.:
Zfish   406 --------------------------ITVSTDGKMCSWSLD------------------MLSQPQ 426

  Fly   614 SAFKSMVIKPTYNLYFPEPITGIIADTSCLSCLTPVAKLIQANPSNYPIKTIAKDPPTMRQSMIV 678
            .:.:.:     ||...|..:|       |::               :|...:        .:.:|
Zfish   427 ESMELI-----YNKSKPVAVT-------CMA---------------FPASDV--------NNYVV 456

  Fly   679 STFYGHVSRIDWQGTYTEGEATEVINSSIPFAMVHDGPVVMVK-KNPFYPELFASIGRT-----I 737
            .:..|.|......|  ::....|:.:.       |.|||..:. .|...|..|:.:..|     .
Zfish   457 GSEEGTVYTASRHG--SKAGIGEIFDG-------HQGPVTGISCHNAVGPVDFSHLFTTSSFDWT 512

  Fly   738 LAIWKEDYNYSPIF-WRKRACDLTAVAWSETRPAVLYLTRIDGILEAWDILARDDDACLTEILGG 801
            :.:|...:| .|:: :...|..:..|.||...||:......:|.|:.|::....:....:..:.|
Zfish   513 VKLWSTKHN-KPLYSFEDNADYVYDVMWSPVHPALFATVDGNGRLDLWNLNNYTEVPSASVSVEG 576

  Fly   802 GIITAITEHRPSLPHKILGIGDYNSSI------RMVKLPHSFD 838
            |  .|:...|.:...:.:.:||....:      ..:.:||:.|
Zfish   577 G--CALNRVRWASGGREVAVGDSEGRVWIYDVGEQLAVPHTDD 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mmm	NP_648138.1	WD40 repeat	462..505	CDD:293791	10/42 (24%)
		WD40 repeat	510..547	CDD:293791	3/36 (8%)
dync1i1b	XP_005158174.1	Dynein_IC2	143..173	CDD:463291	4/29 (14%)
		WD40	286..625	CDD:441893	79/465 (17%)
		WD40 repeat	290..335	CDD:293791	15/62 (24%)
		WD40 repeat	345..386	CDD:293791	10/40 (25%)
		WD40 repeat	392..435	CDD:293791	12/115 (10%)
		WD40 repeat	441..488	CDD:293791	12/85 (14%)
		WD40 repeat	496..528	CDD:293791	6/32 (19%)
		WD40 repeat	534..572	CDD:293791	8/37 (22%)
		WD40 repeat	580..606	CDD:293791	3/25 (12%)