Protein Alignment mmm and dnai4

DIOPT Version :10

• Sequence 1: NP_648138.1
• Gene: mmm / 38851
• FlyBaseID: FBgn0035799
• Length: 1132
• Species: Drosophila melanogaster
• Sequence 2: NP_001018595.1
• Gene: dnai4 / 553797
• ZFINID: ZDB-GENE-050522-322
• Length: 778
• Species: Danio rerio
• Alignment Length: 788
• Identity: 144/788 - (18%)
• Similarity: 266/788 - (33%)
• Gaps: 204/788 - (25%)

  Fly   116 LFDELENSAELMKKFKNFNPEHFILIGFCPLLTEQEDDPPEGEPFI--FYSSIKESKMAMSIIQN 178
            :|..|:.|...|.:|              |.:..|..:.....||.  |:.|...|:::.:....
Zfish    99 VFTALDTSLTTMTEF--------------PSIAFQTTNASLTGPFTRSFFGSASASRISQTAESV 149

  Fly   179 MEHFERWRMQRRLRKKPRRWVSHGTDEEMTIMVERFKDEPID-------VEIQSVYPIQMPRHVA 236
            .:..:...:::.|........||..:.:     |:.::..:|       .|.::::.:.:|   |
Zfish   150 TDETKDLLVKQDLSNSISDIQSHREEPK-----EQLRENILDSTANCYLSETETIWLLDIP---A 206

  Fly   237 FDYRMTRDVRDGVLELLPNENIKWENVTKKR------VNVSVQ--SAPPKIEREQQTNPTFPSNA 293
            ....:..:..:.|.|    .|..:..:.|.|      |..|:|  |..||.:..|..:.|....|
Zfish   207 VSVSLESEDAEAVKE----RNNAYTELCKNRQGNDKYVERSMQTFSDAPKTKEVQCDSITMVDKA 267

  Fly   294 -----WSQYLYEIDDEDLELDETDVDEEEEKKKAQAKP-GTYVEPEKKPPEM------------S 340
                 |..|....:..|:..:.....|..|....::.| |..|.|::....:            |
Zfish   268 VMCTVWDMYDSFNNISDVSANTVVSSERHEATIPESSPEGHLVHPKRSNQSLSVVSTVSTVSGSS 332

  Fly   341 AQIEMLLNTLEFNQIDSYRDDYSLISSRQVVQYTNPYLQEFLCFANISKSNKRFVAGYDWYPKLS 405
            ..||.:...|   .:|...|...::.|.::.|  :..|.|.:..||:.:..   :|.|...|.:.
Zfish   333 THIEKMACVL---PLDEEPDLQLILQSDKLKQ--DLALMERVVLANVFQPK---LAAYRQLPIIE 389

  Fly   406 GLIAVSYAFSTPATVNEATN-RVDYVQRAVLEPNPVLLWSFSDNLNYKLEFEAPIETTALTFCPF 469
            ....|.......:...::.| ...:::|         ||.||      .|.......|.:.:...
Zfish   390 DPDCVQMVMEEESWTEQSKNSHCPFLER---------LWDFS------CELTMGRNVTCMVWNKK 439

  Fly   470 NGDILLGG--------SKNGQVVLWDLQG--------RCEK----LDEEEYLTAAQAKYRIMIGE 514
            |.|:|..|        ..:|.|..|.|:.        .||.    ||    .:|:.|. ::.:|.
Zfish   440 NPDLLAVGYGQVEFKNPNSGLVCCWSLKNPTWPDRVFYCESGVTALD----FSASNAN-QLAVGM 499

  Fly   515 FLNWTI---DIEDNVIVPATISLLDC-----SPKGAITAFYWLGRSIYLSQFGKVYNDPDIRNHH 571
            : :.||   :::.:...|.|.| .||     ||...:|   |:.           :.|....:..
Zfish   500 Y-DGTIAIYNVQTSEQTPITDS-SDCANLHTSPVWQLT---WID-----------HEDGLAADKG 548

  Fly   572 KFFVTCAFDGTISFWDLDGKGGKSAKDKMRNRMLPKELTQSESAFKSM----VIK-PTYNLYFPE 631
            :..|:.:.||.||.|                           ..:|||    ::| ..::|.:.:
Zfish   549 EILVSVSSDGRISKW---------------------------IHYKSMECVDLMKLKIHDLQWKQ 586

  Fly   632 PITGIIADTSCLSCLTPVAKLIQANPSNYPIKTIAKDPPTMRQSMIVSTFYGHVSRIDWQGTYTE 696
            .|          |.||| ......:|::..|             .:|.|..||:.:.  ..:|.|
Zfish   587 HI----------SSLTP-GMCFDFHPNDSKI-------------YLVGTEEGHIHKC--SSSYNE 625

  Fly   697 GEATEVINSSIPFAMVHDGPVVMVKKNPFYPELFASIGRT-ILAIWKEDYNYSPIFWRKRACDLT 760
                :.::|    ...|..||..|..:||..::|.|.... .:.:|::|.....:.:......:.
Zfish   626 ----QYLDS----YKAHKRPVYKVTWSPFCSDVFLSCSSDWTIQLWRQDLQIPVMGFTSGQRVVF 682

  Fly   761 AVAWSETRPAVLYLTRIDGILEAWDILARDDDACLTEILGGGIITAITEHRPSLPHKILGIGDYN 825
            .:.|| ...|.::....:|.:|.||:.....|..|......|:........|.....:  :||..
Zfish   683 DIMWS-PHCATVFGAVSEGKVEIWDLRVSSLDPTLVNWTSPGVNPTALLFSPETDCVL--VGDSE 744

  Fly   826 SSIRMVKL 833
            ..:.:.||
Zfish   745 GQVTVYKL 752

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mmm	NP_648138.1	WD40 repeat	462..505	CDD:293791	14/62 (23%)
		WD40 repeat	510..547	CDD:293791	11/44 (25%)
dnai4	NP_001018595.1	WD40 repeat	431..473	CDD:293791	9/41 (22%)
		WD 1. /evidence=ECO:0000255	477..517		9/45 (20%)
		WD40	479..751	CDD:475233	66/356 (19%)
		WD40 repeat	483..526	CDD:293791	12/49 (24%)
		WD 2. /evidence=ECO:0000255	526..573		14/87 (16%)
		WD40 repeat	531..576	CDD:293791	12/85 (14%)
		WD 3. /evidence=ECO:0000255	586..629		13/72 (18%)
		WD40 repeat	589..624	CDD:293791	10/50 (20%)
		WD 4. /evidence=ECO:0000255	633..673		10/39 (26%)
		WD40 repeat	638..675	CDD:293791	8/36 (22%)
		WD 5. /evidence=ECO:0000255	676..715		8/39 (21%)
		WD40 repeat	681..707	CDD:293791	6/26 (23%)
		WD 6. /evidence=ECO:0000255	721..760		6/34 (18%)