Protein Alignment mmm and Dync2i2

DIOPT Version :10

• Sequence 1: NP_648138.1
• Gene: mmm / 38851
• FlyBaseID: FBgn0035799
• Length: 1132
• Species: Drosophila melanogaster
• Sequence 2: NP_001005542.2
• Gene: Dync2i2 / 296618
• RGDID: 1359465
• Length: 537
• Species: Rattus norvegicus
• Alignment Length: 490
• Identity: 101/490 - (20%)
• Similarity: 161/490 - (32%)
• Gaps: 155/490 - (31%)

  Fly   401 YPKL--SGLIAVSYAFSTPATVNE-ATNRVDYVQRAVLEPNPVLLWSFS-DNLN---YKLEFEAP 458
            ||..  .||.....:::|..:|.. |..|:|......|: :.|..|:.. ..||   ..:..|.|
  Rat   155 YPPAQGQGLHVTGISWNTTGSVLACAYGRLDDGDWGTLK-SYVCTWNLDRQGLNPHQPSVVVEVP 218

  Fly   459 IETTALTFCPFNGDILLGGSKNGQVVLWDLQGRCEKLDEEEYLTAAQAKYRIMIGEFLNWTIDIE 523
            .....|.|.|.....:.||..:|:|::||: .|.|                    :.|.|...:.
  Rat   219 SAVMCLAFHPIQPSHIAGGLYSGEVLVWDM-SRPE--------------------DPLLWRTGLT 262

  Fly   524 DNVIVPATISLLDCSPKGAITAFYWLGRSIYLSQFGKVYNDPDIRNHHKFFV-TCAFDGTISFWD 587
            |:........:|            ||               |:.|:.|:|.| :.|.||.:..|.
  Rat   263 DDTHTDPVYQVL------------WL---------------PEPRHSHRFQVLSAATDGRVLLWR 300

  Fly   588 LDGKGGKSAKDKMRNRMLPKELTQSESAFKSMVIKPTYNLYFPEPITGIIADTSCLSCLTPVAKL 652
            ..|.|               :|..|:.                                  .|..
  Rat   301 GSGAG---------------QLRLSKG----------------------------------FALA 316

  Fly   653 IQANPSNYPIKTIAKDPPTMR-----QSMIVSTFYGHVSRIDWQGTY-------TEGEATEVINS 705
            :|    ..|..|..|.||...     .|:..|:|...:..:..:|.:       .|..|...:.|
  Rat   317 VQ----QLPRSTKLKKPPRGETEVGVTSVAFSSFDSSLFVLGTEGGFPLKCSLAAEAAALTRMPS 377

  Fly   706 SIPF-AMV------HDGPVVMVKKNPFYPELFASIGRTILAIWKEDYNYSPIFWRKRACDLT--- 760
            |:|. |.|      |.|||..|..:||:..||.|.|..         .:..::...:|..||
  Rat   378 SVPLRAPVQFTFSPHGGPVYSVSCSPFHRNLFLSAGTD---------GHVHLYSMLQAQPLTSLQ 433

  Fly   761 -------AVAWSETRPAVLYLTRIDGILEAWDI--LARDDDACLTEILGGGIITAITEHRPSLPH 816
                   ||.||..||.|......:|.::.:|:  .::.....:|:...|..:..:..:  |...
  Rat   434 LSHKYLFAVRWSPVRPLVFAAASGEGDVQLFDLQKSSQKPTVSITQTQDGSPVYCLEFN--SQQT 496

  Fly   817 KILGIGDYNSSIRMVKLPHSFDVPLPNE---LDQL 848
            ::|..||....:::.:|..:|....|.|   ||||
  Rat   497 QLLAAGDAKGVVKVWQLSTAFTEQGPREAEDLDQL 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mmm	NP_648138.1	WD40 repeat	462..505	CDD:293791	11/42 (26%)
		WD40 repeat	510..547	CDD:293791	4/36 (11%)
Dync2i2	NP_001005542.2	WD40	50..515	CDD:441893	94/472 (20%)
		WD40 repeat	165..211	CDD:293791	10/46 (22%)
		WD40 repeat	223..265	CDD:293791	14/62 (23%)
		WD40 repeat	271..309	CDD:293791	15/79 (19%)
		WD40 repeat	339..389	CDD:293791	11/49 (22%)
		WD40 repeat	396..433	CDD:293791	11/45 (24%)
		WD40 repeat	439..479	CDD:293791	9/39 (23%)
		WD40 repeat	486..511	CDD:293791	4/26 (15%)