Protein Alignment mmm and Sdic4

DIOPT Version :10

• Sequence 1: NP_648138.1
• Gene: mmm / 38851
• FlyBaseID: FBgn0035799
• Length: 1132
• Species: Drosophila melanogaster
• Sequence 2: NP_001368966.1
• Gene: Sdic4 / 2768886
• FlyBaseID: FBgn0053499
• Length: 554
• Species: Drosophila melanogaster
• Alignment Length: 712
• Identity: 134/712 - (18%)
• Similarity: 217/712 - (30%)
• Gaps: 280/712 - (39%)

  Fly   269 NVSVQSAPPK----IEREQQTNPTFPSNAWSQYLYEIDDEDLELDETDVDEEEEKKK------AQ 323
            ||...:.|||    ..::.||..|...|.          :.|..|....|||...:.      ::
  Fly    30 NVQATNIPPKETLVYTKQTQTTSTGGGNG----------DVLAFDAQGDDEESSLQNLGNGFTSK 84

  Fly   324 AKPG--TY-------VEPEKKPPEMSAQIEMLLNTLEFNQIDSYRDDYSLIS------------- 366
            ..||  |:       |.|...|.|:..:.|:   ..|.|::...:....::|
  Fly    85 LPPGYLTHGLPTVKDVAPAITPLEIKKETEV---KKEVNELSEEQKQMIILSENFQRFVVRAGRV 146

  Fly   367 -----SRQVVQYTNPYL-----QEFLCFANISKSNKRF----------------VAGYDWYPKLS 405
                 |..|..||: |:     :|    ||..:|:.|.                :...||.....
  Fly   147 IERALSENVDIYTD-YIGGGDSEE----ANDERSHARLSLNRVFYDERWSKNRCITSMDWSTHFP 206

  Fly   406 GLIAVSYAFSTPATVNEATNRVDYVQRAVLEPNPVLLWSFSDNLNYKLE-----FEAPIETTALT 465
            .|:..||..:     .|:.|..|.|         |::|    |..:|..     |.......:..
  Fly   207 ELVVGSYHNN-----EESPNEPDGV---------VMVW----NTKFKKSTPEDVFHCQSAVMSTC 253

  Fly   466 FCPFNGDILLGGSKNGQVVLWDLQGRCEKLD--EEEYLTAAQAKYRI----MIGEFLNWTIDIED 524
            |..||.:::|||:.:||:||||  .|.:|..  :...|:||...:.:    |:|
  Fly   254 FAKFNPNLILGGTYSGQIVLWD--NRVQKRTPIQRTPLSAAAHTHPVYCLQMVG----------- 305

  Fly   525 NVIVPATISLLDCSPKGAITAFYWLGRSIYLSQFGKVYNDPDIRNHHKFFVTCAFDGTISFWDLD 589
                                                      .:|.|. .::.:.||.:..|.||
  Fly   306 ------------------------------------------TQNAHN-VISISSDGKLCSWSLD 327

  Fly   590 GKGGKSAKDKMRNRMLPK-----ELTQSESAFKSMVIKPTYNLYFPEPITGIIADTSCLSCLTPV 649
                          ||.:     ||.|.:|  |::.|.   ::.||
  Fly   328 --------------MLSQPQDTLELQQRQS--KAIAIT---SMAFP------------------- 354

  Fly   650 AKLIQANPSNYPIKTIAKDPPTMRQSMIVSTFYGHVSRIDWQGTYTEGEATEVINSSIPFAMVHD 714
                 ||..|               |:::.:..|:|......|  ......||...       |.
  Fly   355 -----ANEIN---------------SLVMGSEDGYVYSASRHG--LRSGVNEVYER-------HL 390

  Fly   715 GPVVMVKKNPFYPELFASIGRTILA----IWKEDYNYS--------------PIFWRKRACD-LT 760
            ||:..:..:  |.:|....|...|.    ||......|              |::..:...| :.
  Fly   391 GPITGISTH--YNQLSPDFGHLFLTSSIKIWSLKLPISSCQFSVVSGINSNKPLYSFEDNSDYMM 453

  Fly   761 AVAWSETRPAVLYLTRIDGILEAWDILARDDDACLTEILGGGIITAITEHRPSLPHKILGIGDYN 825
            .||||...||:.......|.|:.|::   :.|   ||:....|:.|   ..|:|.
  Fly   454 DVAWSPVHPALFAAVDGSGRLDLWNL---NQD---TEVPTASIVVA---GAPALN---------- 499

  Fly   826 SSIRMVKLPHSFDVPLPNELDQLIKYVLKEERRKMGIQSWEQKYYELNKDIIEAKREAAAEI 887
               |:...|....|.:.:|..:|..|.:.|...:.....|.:    .|..:.|.|...:.|:
  Fly   500 ---RVSWTPSGLHVCIGDEAGKLYVYDVAENLAQPSRDEWSR----FNTHLSEIKMNQSDEV 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mmm	NP_648138.1	WD40 repeat	462..505	CDD:293791	16/44 (36%)
		WD40 repeat	510..547	CDD:293791	2/40 (5%)
Sdic4	NP_001368966.1	Dynein_IC2	21..51	CDD:463291	6/20 (30%)
		WD40	196..523	CDD:475233	92/491 (19%)
		WD40 repeat	196..245	CDD:293791	14/66 (21%)
		WD40 repeat	251..289	CDD:293791	14/39 (36%)
		WD40 repeat	298..337	CDD:293791	11/106 (10%)
		WD40 repeat	349..446	CDD:293791	22/149 (15%)
		WD40 repeat	452..490	CDD:293791	12/43 (28%)
		WD40 repeat	498..524	CDD:293791	7/38 (18%)