Protein Alignment frac and Fbln7

DIOPT Version :10

• Sequence 1: NP_648137.3
• Gene: frac / 38850
• FlyBaseID: FBgn0035798
• Length: 1618
• Species: Drosophila melanogaster
• Sequence 2: NP_077199.2
• Gene: Fbln7 / 70370
• MGIID: 1917620
• Length: 440
• Species: Mus musculus
• Alignment Length: 325
• Identity: 94/325 - (28%)
• Similarity: 129/325 - (39%)
• Gaps: 75/325 - (23%)

  Fly   813 ELTPDG--FGCADIDECSQDYGNCSDICINLLGTHACACERGYELAKDKLSCLDVDECAGLLSGG 875
            |..|||  ||...:.: .:.|..|:. ...|:|..:..|........::..|.|:.||:   |..
Mouse    85 EAPPDGKKFGSKYLVD-HEVYFTCNP-GFQLVGPSSVVCLANGSWTGEQPRCRDISECS---SQP 144

  Fly   876 CSH--ECINKAGTFECGCPLGYILN-----------DDGRSCSPALVGCPPGTQRSADGCAPIE- 926
            |.:  .|:.....:.|.||.|...|           |.|.:..||....|        .||.:|
Mouse   145 CHNGGTCVEGINHYRCICPPGKTGNRCQHQTQAAAPDGGEAGDPAFSRAP--------RCAQVER 201

  Fly   927 -----CNPGY----TLGSDDKCVDIDECQ--KQNGG---CSHRCSNTEGSFKCSCPPGYELDSDQ 977
                 |..|:    |.|....|.|::||:  .|.|.   |.|.|.||.||::|:||.||.:.:|.
Mouse   202 EQHCSCEAGFHLSSTTGGHSVCQDVNECEIYGQKGRPRLCMHACVNTPGSYRCTCPSGYRILADG 266

  Fly   978 KTCQDIDECDQDKTSCITG-TCINEIGGFRCEFPKFPVLPEIPTASSLPESPKIELKTPKYPDFT 1041
            |:|:|:|||...:..|..| ||||..|||:|      |.||.|..|.       .:...|...|.
Mouse   267 KSCEDVDECAGPQHMCPRGTTCINTGGGFQC------VNPECPEGSG-------NISYVKTSPFQ 318

  Fly  1042 ELSNEIPENPK------KPAEFDYPEPKFPSLPKWEGLPKL-PPLADIPTSKAPVPLRPEVPKSL 1099
            ...|..|.:.:      |...|.|     .|||.     || .|:.....:.|.:|..|. |.||
Mouse   319 CERNPCPMDSRPCRHLPKTISFHY-----LSLPS-----KLKTPITLFRMATASIPGHPG-PNSL 372

  Fly  1100  1099
            Mouse   373  372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
frac	NP_648137.3	FXa_inhibition	296..331	CDD:464251
		cEGF	396..415	CDD:463661
		FXa_inhibition	425..458	CDD:464251
		FXa_inhibition	476..505	CDD:464251
		EGF_CA	552..>581	CDD:214542
		FXa_inhibition	596..630	CDD:464251
		FXa_inhibition	636..>664	CDD:464251
		EGF_CA	676..711	CDD:214542
		FXa_inhibition	745..780	CDD:464251
		FXa_inhibition	786..821	CDD:464251	5/9 (56%)
		vWFA	<821..861	CDD:469594	5/39 (13%)
		FXa_inhibition	874..904	CDD:464251	9/42 (21%)
		FXa_inhibition	945..980	CDD:464251	17/39 (44%)
		PTZ00449	<1017..>1098	CDD:185628	20/87 (23%)
		CCP	1110..1170	CDD:153056
		CCP	1183..1235	CDD:153056
		HYR	1468..1536	CDD:460572
Fbln7	NP_077199.2	CCP	81..135	CDD:153056	11/51 (22%)
		EGF_CA	136..172	CDD:238011	11/38 (29%)
		FXa_inhibition	241..269	CDD:464251	14/27 (52%)
		EGF_CA	271..305	CDD:429571	18/39 (46%)