DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment frac and fbln5

DIOPT Version :9

Sequence 1:NP_001137905.1 Gene:frac / 38850 FlyBaseID:FBgn0035798 Length:1618 Species:Drosophila melanogaster
Sequence 2:NP_001025619.1 Gene:fbln5 / 595007 XenbaseID:XB-GENE-983056 Length:439 Species:Xenopus tropicalis


Alignment Length:402 Identity:122/402 - (30%)
Similarity:162/402 - (40%) Gaps:128/402 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   636 CLVNNGGCQQVCRNLPGSYGCICAAGYELLKLDGIRGYCFDIDECSQRTHGCSDQMLCENLNGSY 700
            |:.::...||.|.|           |:|   :|...|.|.|:|||......|...|:|.|.||.|
 Frog    15 CITDSVHAQQQCTN-----------GFE---MDRSTGQCLDVDECRIILDACRGDMMCVNQNGGY 65

  Fly   701 TCL-----------------------------CPP-------GYALGLDNHIVTSLNSSFITDST 729
            .|:                             .||       ||.:..|.               
 Frog    66 LCIPRTNTMFRPSFRNPFLPAAAAPLPPPNFPSPPRPLICRFGYQIDEDQ--------------- 115

  Fly   730 SSETPSAHTCLDIDECSLANGNC--SHFCQNEPGGFQCACPLGYALSEDMRTCQDIDECLDSNGQ 792
                     |:|||||:.....|  :..|.|..||:.|:|..||.|.|..  |.|||||  ..|.
 Frog   116 ---------CVDIDECASETHQCNPTQICINTEGGYTCSCTEGYWLLEGQ--CLDIDEC--RYGY 167

  Fly   793 CSQLCLNQPGGFACACETGFELTPDGFGCADIDECSQDYGNCSDICINLLGTHACACERGYELAK 857
            |.|||.|.||.::|.|..||.|..||..|.|:|||..| ..|...|:|..|::.|.||.||||.:
 Frog   168 CQQLCANVPGSYSCTCNPGFILNTDGRSCQDVDECITD-NPCVQTCMNTYGSYLCRCEAGYELDE 231

  Fly   858 DKLSCLDVDECAGLLSGGCSHECINKAGTFECGCPLGYILNDDGRSCSPALVGCPPGTQRSADGC 922
            |.::|.|:|||: :....|.|:|:|:.|::.|.||.||:|.||.|:|.                 
 Frog   232 DGVNCSDMDECS-VSEFLCQHDCVNEPGSYYCRCPEGYVLLDDSRTCQ----------------- 278

  Fly   923 APIECNPGYTLGSDDKCVDIDECQKQNGGCS--HRCSNTEGSFKC----SCPPGYELDSDQKTCQ 981
                              |||||...|..|:  ..|.|..||::|    .|...|...:|.: |.
 Frog   279 ------------------DIDECDTGNNTCTLQQLCFNIPGSYRCLDTVRCEDPYIQINDNR-CM 324

  Fly   982 DIDECDQDKTSC 993
                |..:.|:|
 Frog   325 ----CPVENTAC 332

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fracNP_001137905.1 FXa_inhibition 296..331 CDD:291342
cEGF 396..415 CDD:289433
FXa_inhibition 425..458 CDD:291342
FXa_inhibition 476..505 CDD:291342
vWFA <550..586 CDD:294047
FXa_inhibition 596..630 CDD:291342
FXa_inhibition 636..>664 CDD:291342 6/27 (22%)
EGF_CA 676..715 CDD:284955 17/74 (23%)
FXa_inhibition 745..780 CDD:291342 12/36 (33%)
FXa_inhibition 786..821 CDD:291342 16/34 (47%)
FXa_inhibition 827..862 CDD:291342 14/34 (41%)
FXa_inhibition 874..904 CDD:291342 14/29 (48%)
FXa_inhibition 945..980 CDD:291342 11/40 (28%)
CCP 1110..1170 CDD:153056
CCP 1183..1235 CDD:153056
DUF5011 1468..1536 CDD:295940
fbln5NP_001025619.1 vWFA <103..156 CDD:381780 20/76 (26%)
cEGF 178..201 CDD:372248 9/22 (41%)
EGF_CA 198..236 CDD:214542 17/38 (45%)
vWFA <236..276 CDD:381780 18/40 (45%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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