DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment frac and si:dkey-258f14.3

DIOPT Version :9

Sequence 1:	NP_001137905.1	Gene:	frac / 38850	FlyBaseID:	FBgn0035798	Length:	1618	Species:	Drosophila melanogaster
Sequence 2:	XP_021334056.1	Gene:	si:dkey-258f14.3 / 571152	ZFINID:	ZDB-GENE-050809-43	Length:	526	Species:	Danio rerio

Alignment Length:	223	Identity:	63/223 - (28%)
Similarity:	98/223 - (43%)	Gaps:	47/223 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   410 CQDINECEVDGPEDLDNNAVCQQKCEN-TIGSFRCTCVEGYHLLEDQRSCALDSCTDLENPQLNR 473
            |..:|:|. ||.:::        .|.| |.|||.|...|         ||...|..
Zfish    57 CDAVNDCG-DGSDEI--------SCWNCTNGSFHCVASE---------SCVSSSSV--------- 94

  Fly   474 TRCAHECQDLPEGSYRCVCPKGYELSEDQHSCLVQESPCSTEKGVEKCSPGTCLASEDNTSFSCI 538
                  |...|:      |..|.:...|..:...|..||:..:..  |:.|.|:.:......|..
Zfish    95 ------CDGRPD------CADGADEQLDTCTSFSQAQPCARSEFT--CTNGQCVPNSWRCDHSSD 145

  Fly   539 CPTGYRSEAFSCQDIDECAEDTHLCSHTCQNTPGGYQCQCPEGLNLVEEYTCLAENLCEVNNNGC 603
            |..|  |:...| |.:|||.:...|||||.:.|.|::|.||:|:.||::..|...:.| ::.:.|
Zfish   146 CKDG--SDEEDC-DHNECAVNNGGCSHTCIDLPFGFRCDCPKGMRLVQDTHCEVVDQC-LDADVC 206

  Fly   604 EQICLTARGG-VCACREGFRLSADGKSC 630
            :|||:.:.|. ||.|::|::|:|....|
Zfish   207 DQICVHSNGSVVCDCQDGYQLTAGTGQC 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
frac	NP_001137905.1	FXa_inhibition	296..331	CDD:291342
		cEGF	396..415	CDD:289433	1/4 (25%)
		FXa_inhibition	425..458	CDD:291342	8/33 (24%)
		FXa_inhibition	476..505	CDD:291342	5/28 (18%)
		vWFA	<550..586	CDD:294047	17/35 (49%)
		FXa_inhibition	596..630	CDD:291342	12/34 (35%)
		FXa_inhibition	636..>664	CDD:291342
		EGF_CA	676..715	CDD:284955
		FXa_inhibition	745..780	CDD:291342
		FXa_inhibition	786..821	CDD:291342
		FXa_inhibition	827..862	CDD:291342
		FXa_inhibition	874..904	CDD:291342
		FXa_inhibition	945..980	CDD:291342
		CCP	1110..1170	CDD:153056
		CCP	1183..1235	CDD:153056
		DUF5011	1468..1536	CDD:295940
si:dkey-258f14.3	XP_021334056.1	LDLa	38..72	CDD:238060	5/23 (22%)
		PRKCSH-like	<45..>112	CDD:193472	21/93 (23%)
		LDLa	121..155	CDD:238060	8/37 (22%)
		FXa_inhibition	160..193	CDD:317114	15/32 (47%)
		Ldl_recept_b	367..407	CDD:278487
		LY	393..433	CDD:214531
		LY	434..476	CDD:214531
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000