DRSC/TRiP Functional Genomics Resources

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Protein Alignment frac and fbln5

DIOPT Version :9

Sequence 1:NP_001137905.1 Gene:frac / 38850 FlyBaseID:FBgn0035798 Length:1618 Species:Drosophila melanogaster
Sequence 2:NP_001005979.1 Gene:fbln5 / 449806 ZFINID:ZDB-GENE-041010-54 Length:477 Species:Danio rerio


Alignment Length:475 Identity:132/475 - (27%)
Similarity:171/475 - (36%) Gaps:173/475 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   581 GLNLVEEYTCLAENLCEVNNNGCEQICLTARGGVCACREGFRLSADGKSCEDVDECLVNNGGCQQ 645
            ||:|:.....|:..||.|        |....|....|.:||......:.|.|:||          
Zfish     7 GLSLLSSKRMLSVVLCIV--------CSINYGKSQTCSDGFTFDRRSRQCMDIDE---------- 53

  Fly   646 VCRNLPGSYGCICAAGYELLKLDGIRGYCFDIDECSQRTHGCSDQMLCENLNGSYTCL------- 703
             ||.||..                                 |...|.|.|.||.|.|:       
Zfish    54 -CRTLPDP---------------------------------CRGDMRCVNQNGGYLCMPRGLYSQ 84

  Fly   704 --------------------------------------CP-PGYALGLDNHIVTS-----LNSSF 724
                                                  .| ||...|....||:.     |..:|
Zfish    85 SYGRNSPLPYPEASYPEEPYPDRSLGYSETYSAPVAPVAPGPGPGPGPSYPIVSRTTPCLLGYTF 149

  Fly   725 ITDSTSSETPSAHTCLDIDECSLANGNC--SHFCQNEPGGFQCACPLGYALSEDMRTCQDIDECL 787
            ..|.         ||:|:|||...:..|  :..|.|..||:.|:|..||.|....  ||||||| 
Zfish   150 GADG---------TCVDVDECEAESHQCNPTQVCINTAGGYTCSCTEGYWLVGGQ--CQDIDEC- 202

  Fly   788 DSNGQCSQLCLNQPGGFACACETGFELTPDGFGCADIDECSQDYGNCSDICINLLGTHACACERG 852
             ..|.|.|||.|.||.::|:|..||.|..|...|.|:|||..|  .||..|:|..|:..|.|:.|
Zfish   203 -RYGYCQQLCANVPGSYSCSCSPGFLLNTDARTCQDVDECVTD--PCSHGCLNTYGSFMCTCDEG 264

  Fly   853 YELAKDKLSCLDVDEC--AGLLSGGCSHECINKAGTFECGCPLGYILNDDGRSCSPALVGCPPGT 915
            :|||.|..:|.|:|||  :..|   |.|.|:|..|:|.|.||.||.:.:|||||.          
Zfish   265 FELAADDTTCNDLDECSFSDFL---CQHTCVNAPGSFSCACPSGYYVYEDGRSCE---------- 316

  Fly   916 QRSADGCAPIECNPGYTLGSDDKCVDIDECQKQNGGCSHR--CSNTEGSFKC----SCPPGY-EL 973
                                     |::||:..|..|:..  |.|.:|.:.|    .|.|.| ||
Zfish   317 -------------------------DLNECESGNNTCTTEQVCFNFQGGYTCLNPLRCDPPYIEL 356

  Fly   974 DSDQKTCQDIDECDQDKTSC 993
            ..:|  |.    |..:..:|
Zfish   357 SDNQ--CM----CSAENPAC 370

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fracNP_001137905.1 FXa_inhibition 296..331 CDD:291342
cEGF 396..415 CDD:289433
FXa_inhibition 425..458 CDD:291342
FXa_inhibition 476..505 CDD:291342
vWFA <550..586 CDD:294047 3/4 (75%)
FXa_inhibition 596..630 CDD:291342 7/33 (21%)
FXa_inhibition 636..>664 CDD:291342 4/27 (15%)
EGF_CA 676..715 CDD:284955 12/84 (14%)
FXa_inhibition 745..780 CDD:291342 11/36 (31%)
FXa_inhibition 786..821 CDD:291342 15/34 (44%)
FXa_inhibition 827..862 CDD:291342 14/34 (41%)
FXa_inhibition 874..904 CDD:291342 14/29 (48%)
FXa_inhibition 945..980 CDD:291342 13/41 (32%)
CCP 1110..1170 CDD:153056
CCP 1183..1235 CDD:153056
DUF5011 1468..1536 CDD:295940
fbln5NP_001005979.1 vWFA <155..191 CDD:294047 14/35 (40%)
vWFA <191..234 CDD:294047 22/46 (48%)
vWFA <235..273 CDD:294047 18/39 (46%)
vWFA <274..314 CDD:294047 19/42 (45%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24034
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
ZFIN 00.000 Not matched by this tool.
43.970

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