DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment frac and matn1

DIOPT Version :9

Sequence 1:	NP_001137905.1	Gene:	frac / 38850	FlyBaseID:	FBgn0035798	Length:	1618	Species:	Drosophila melanogaster
Sequence 2:	NP_001093210.1	Gene:	matn1 / 403023	ZFINID:	ZDB-GENE-050307-3	Length:	489	Species:	Danio rerio

Alignment Length:	177	Identity:	45/177 - (25%)
Similarity:	67/177 - (37%)	Gaps:	70/177 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   361 EPLEENPEITE---VVENPIEKTNEVPVNVSESQPAGKTCNSGFQLSADGTDCQDINECEVDGPE 422
            ||||::.:..|   ::|...:|..|                         ..|..:::....|..
Zfish   190 EPLEDHVDYVESYSLIEKLTKKFQE-------------------------AFCAVVSDLCATGDH 229

  Fly   423 DLDNNAVCQQKCENTIGSFRCTCVEGYHLLEDQRSCALDSCTDLENPQLNRTRCAHECQD---LP 484
            |      |:..|.:|.|||:|.|.||:.|:.|.|||               :.|::...|   |.
Zfish   230 D------CEHICISTPGSFKCACREGFTLMNDSRSC---------------SACSNAATDVVFLI 273

  Fly   485 EGSYRCVCPKGYEL--------------SE-DQHSCLVQESPCSTEK 516
            :|| :.|.|:.:||              || :.|..|||.|  ||.|
Zfish   274 DGS-KSVRPENFELVKKWINLIIDKLDVSETNTHVGLVQYS--STVK 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
frac	NP_001137905.1	FXa_inhibition	296..331	CDD:291342
		cEGF	396..415	CDD:289433	1/18 (6%)
		FXa_inhibition	425..458	CDD:291342	13/32 (41%)
		FXa_inhibition	476..505	CDD:291342	12/46 (26%)
		vWFA	<550..586	CDD:294047
		FXa_inhibition	596..630	CDD:291342
		FXa_inhibition	636..>664	CDD:291342
		EGF_CA	676..715	CDD:284955
		FXa_inhibition	745..780	CDD:291342
		FXa_inhibition	786..821	CDD:291342
		FXa_inhibition	827..862	CDD:291342
		FXa_inhibition	874..904	CDD:291342
		FXa_inhibition	945..980	CDD:291342
		CCP	1110..1170	CDD:153056
		CCP	1183..1235	CDD:153056
		DUF5011	1468..1536	CDD:295940
matn1	NP_001093210.1	vWA_Matrilin	35..258	CDD:238752	23/98 (23%)
matn1	NP_001093210.1	vWA_Matrilin	265..489	CDD:238752	18/56 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910