Protein Alignment frac and Creld

DIOPT Version :10

• Sequence 1: NP_648137.3
• Gene: frac / 38850
• FlyBaseID: FBgn0035798
• Length: 1618
• Species: Drosophila melanogaster
• Sequence 2: NP_608490.1
• Gene: Creld / 33166
• FlyBaseID: FBgn0031217
• Length: 374
• Species: Drosophila melanogaster
• Alignment Length: 418
• Identity: 102/418 - (24%)
• Similarity: 141/418 - (33%)
• Gaps: 141/418 - (33%)

  Fly   161 PPPPPPPP------VVD--------------GADSKPEPQIVIEINDDHANEVVESEPALAETE- 204
            |..|.|||      :|.              |.|:..|        ::.......||..|.|.:
  Fly    23 PEKPVPPPCRACTQLVSSFRAGLERTKRGHAGGDTAWE--------EEKLRSYKNSEVRLVEIQE 79

  Fly   205 ---TENEVLENETPLKAEVQTDVLNSSNASVKVTNDPYEPTFLDNNCGEDNGGCAHICKRLLYPD 266
               :|.||:..:.......:.:.|.......|.|..|...::|   |.:....|.
  Fly    80 KLCSEGEVINKDHCHNLANEHEALLEDWFIHKQTESPDLQSWL---CIDQLTVCC---------- 131

  Fly   267 ENQPINKCDCREGYTLDPNDYASCLDIDECLESNGGCSEICENLPGEYKCSCQEGYYLDESGKSC 331
               |:|        |..|:    ||...|| ..||.|.. .....|..||.|..||    :|.:|
  Fly   132 ---PLN--------TYGPD----CLTCTEC-NGNGKCKG-DGTRKGNGKCKCDPGY----AGPNC 175

  Fly   332 VDINECANPE-----------LSSNCQGACENLPGSYRCVEPLEENPEITEVVENPIEKTNEVPV 385
               ||| .||           |.:.|..||    |...|                    |...|.
  Fly   176 ---NEC-GPEHYESFRDEKKLLCTQCHAAC----GEGGC--------------------TGGGPK 212

  Fly   386 NVSESQPAGKTCNSGFQLSADGTDCQDINEC-EVDGPEDLDNNAVCQQKCENTIGSFRCTCVEGY 449
            :.       :.|..|:.:.:: ..|.||||| |...|    |....||.|.|..|||.|
  Fly   213 SC-------RKCKKGWSMDSE-AGCVDINECLEQQRP----NPCRPQQFCVNNEGSFSC------ 259

  Fly   450 HLLEDQRSCALDSCTDLENPQLNRTRCAHECQDLPEGSYRCVCPKGYELSEDQHSCLVQESPCST 514
              ||..|||  |.| |.:.|.:.| :|| :..:|.||       |.:::|.:|.|..|..:...|
  Fly   260 --LECDRSC--DGC-DGDGPDMCR-KCA-DGYELKEG-------KCHDISAEQRSNYVSFTRMLT 310

  Fly   515 EKGVEKCSPGTCLASEDNTSFSCICPTG 542
            ..|:  | ..||:..:.:|..:..|..|
  Fly   311 YFGM--C-VATCVIFQSSTHIAWGCIVG 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
frac	NP_648137.3	FXa_inhibition	296..331	CDD:464251	11/34 (32%)
		cEGF	396..415	CDD:463661	5/18 (28%)
		FXa_inhibition	425..458	CDD:464251	12/32 (38%)
		FXa_inhibition	476..505	CDD:464251	8/28 (29%)
		EGF_CA	552..>581	CDD:214542
		FXa_inhibition	596..630	CDD:464251
		FXa_inhibition	636..>664	CDD:464251
		EGF_CA	676..711	CDD:214542
		FXa_inhibition	745..780	CDD:464251
		FXa_inhibition	786..821	CDD:464251
		vWFA	<821..861	CDD:469594
		FXa_inhibition	874..904	CDD:464251
		FXa_inhibition	945..980	CDD:464251
		PTZ00449	<1017..>1098	CDD:185628
		CCP	1110..1170	CDD:153056
		CCP	1183..1235	CDD:153056
		HYR	1468..1536	CDD:460572
Creld	NP_608490.1	DUF3456	31..130	CDD:463404	17/109 (16%)
		EGF_CA	231..>259	CDD:214542	15/31 (48%)
		FU	258..293	CDD:214589	17/54 (31%)