DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment frac and efemp1

DIOPT Version :9

Sequence 1:NP_001137905.1 Gene:frac / 38850 FlyBaseID:FBgn0035798 Length:1618 Species:Drosophila melanogaster
Sequence 2:XP_009305317.1 Gene:efemp1 / 100332567 ZFINID:ZDB-GENE-130403-1 Length:444 Species:Danio rerio


Alignment Length:387 Identity:118/387 - (30%)
Similarity:164/387 - (42%) Gaps:88/387 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   658 CAAGYELLKLDGIRGYCFDIDECSQRTHGCSDQMLCENLNGSYTCLCPPGYALGLDNHIVTSLNS 722
            |..|||   .|..:..|.|||||...:..|...|.|.|..|.|.|         |..:....:|.
Zfish    28 CTEGYE---YDPFKEVCTDIDECVLVSDACKAGMKCINHYGGYLC---------LPQNAQIFINK 80

  Fly   723 SFITDSTSSETPSAHTCLDIDECSLANGNCSHFCQNEPGGFQCACPLGYALSEDMRTCQDIDECL 787
            ......:|...|..||  :.:..|.||           ||.||:.  |:. .:....|.|:|||.
Zfish    81 ENEASQSSDSVPQTHT--ETNHRSAAN-----------GGSQCSA--GFT-RDQHNYCHDVDECS 129

  Fly   788 DSNGQC--SQLCLNQPGGFACACETGFELTPDGFGCADIDECSQDYGNCSDICINLLGTHACACE 850
            .....|  .|:|.|..|.::|.|:.|::  ..|..|.|.:||...: .|...|:|..|::.|.|.
Zfish   130 QGLHTCGSDQICYNSRGSYSCQCQPGYQ--RHGEQCVDRNECLLSH-YCMHRCVNTAGSYYCECN 191

  Fly   851 RGYELAKDKLSCLDVDECAGLLSGGCSHECINKAGTFECGCPLGYILNDDGRSCSPALVGCPPGT 915
            .||:||.:..||:||:||.  :|..|.|:|.|..|:|.|                          
Zfish   192 DGYQLASNNHSCVDVNECE--VSQPCQHQCFNLLGSFIC-------------------------- 228

  Fly   916 QRSADGCAPIECNPGYTLGSDD-KCVDIDECQKQNGGCSHRCSNTEGSFKCSCPPGYELDSDQKT 979
                      :|..||.||.|. .|||||||...:..|.:.|.|:||.:.|:||.||::.. .:.
Zfish   229 ----------QCEQGYELGPDAVSCVDIDECSFSSYMCQYACVNSEGGYSCTCPDGYQIHR-TRM 282

  Fly   980 CQDIDECDQDKTSCITG-TCINEIGGFRCEFPKFPVL-PEIPTASS------------LPES 1027
            ||||:||:.....|... .|.|..||.|| :|:.|.| |.:.|:.:            ||:|
Zfish   283 CQDINECETAAHECREDEMCWNYYGGHRC-YPRNPCLEPYVRTSENRCSCQSAAACRGLPQS 343

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fracNP_001137905.1 FXa_inhibition 296..331 CDD:291342
cEGF 396..415 CDD:289433
FXa_inhibition 425..458 CDD:291342
FXa_inhibition 476..505 CDD:291342
vWFA <550..586 CDD:294047
FXa_inhibition 596..630 CDD:291342
FXa_inhibition 636..>664 CDD:291342 3/5 (60%)
EGF_CA 676..715 CDD:284955 13/38 (34%)
FXa_inhibition 745..780 CDD:291342 8/34 (24%)
FXa_inhibition 786..821 CDD:291342 10/36 (28%)
FXa_inhibition 827..862 CDD:291342 11/34 (32%)
FXa_inhibition 874..904 CDD:291342 7/29 (24%)
FXa_inhibition 945..980 CDD:291342 11/34 (32%)
CCP 1110..1170 CDD:153056
CCP 1183..1235 CDD:153056
DUF5011 1468..1536 CDD:295940
efemp1XP_009305317.1 EGF_CA 124..164 CDD:238011 13/41 (32%)
vWFA <163..200 CDD:294047 14/37 (38%)
EGF_CA 205..239 CDD:214542 17/71 (24%)
EGF_CA 245..>276 CDD:304395 14/30 (47%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.