Protein Alignment frac and cd248b

DIOPT Version :10

• Sequence 1: NP_648137.3
• Gene: frac / 38850
• FlyBaseID: FBgn0035798
• Length: 1618
• Species: Drosophila melanogaster
• Sequence 2: XP_021324763.1
• Gene: cd248b / 100002565
• ZFINID: ZDB-GENE-050309-46
• Length: 668
• Species: Danio rerio
• Alignment Length: 701
• Identity: 183/701 - (26%)
• Similarity: 256/701 - (36%)
• Gaps: 176/701 - (25%)

  Fly   446 VEGYHLLEDQRSCALDSCTDLENPQLNRTRCAHECQDLPEGSYRCVCPKGYELSEDQHSCL---V 507
            |.|..|.|....|..|.|..:...:......:..|:| ..|:...:  ||.|.:...|:.|   |
Zfish    29 VMGQSLQEQDGMCDADGCYSIHLQRKTFRESSRICKD-KGGNLATI--KGPEEASLIHNLLSSGV 90

  Fly   508 QESPCSTEK---GVEKCSPGTCLASEDNTSFSCICPTGYRSEAFSCQDIDE----CAEDTHLCSH 565
            :..|....:   |::: .|..|.|:.....|:  ..||.:...::....|:    ||  .|.|..
Zfish    91 RRVPRPRIRLWIGLQR-MPRQCSATRPLRGFT--WSTGEQETQYTNWQRDDVPNACA--AHRCVV 150

  Fly   566 TCQNTPGGYQCQCPEGLNLVEEYTCLAENLCEVNNNGCEQICLTARGGVCACREGFRLSADGKSC 630
            ...||                           .:.:|.:|.......|.||      ::.||..|
Zfish   151 ISYNT---------------------------ADKSGSDQNNFKWLDGSCA------VAVDGFLC 182

  Fly   631 ----EDVDECLVNNGG-----------CQQVCRNLPGSYGCI----CAAGYE-------LLKLDG 669
                :.:...|.|.||           ...:..::|  :|.:    |..|.:       :::.||
Zfish   183 SYTYQGMCPALQNEGGGPALYNTPFELASTILTHVP--FGSVANLPCREGEKEDQSVLCMVRDDG 245

  Fly   670 IRGY------CFDI--DECSQRTHGCSDQMLCENLNGSYTCLCPPGYALGLDNHIVTSLNSSFIT 726
            ..|:      |.||  |.|.|...||  :..|||.|..|.|.|..||.||.|
Zfish   246 SIGWSKDAPLCTDIPKDLCEQDNGGC--EHYCENRNTHYYCECSEGYVLGED------------- 295

  Fly   727 DSTSSETPSAHTCLDIDECSLANGNCSHFCQNEPGGFQCACPLGYALSEDMRTCQDIDECLDSNG 791
                     ..||...|.|..|  ||...|::...|.:|.||.||.||.|.::|.||||||..
Zfish   296 ---------GKTCQLSDPCHRA--NCEFECESTAQGHRCKCPDGYLLSGDGQSCLDIDECLQK-- 347

  Fly   792 QCSQLCLNQPGGFACACETGFELTPDGFGCADIDECSQDYGNCSDICINLLGTHACACERGYE-L 855
            .|.|.|:|.||.|.|.|..|: ||.:...|.|:|||.:  |.|..||.||.|::.|.|..|:. |
Zfish   348 PCPQECINAPGTFECRCNEGY-LTSEFGECVDVDECME--GKCDHICENLNGSYTCLCHEGFSPL 409

  Fly   856 AKDKLSCLDVDECAGLLSGGCSHECINKAGTFECGCPLGYILNDDGRSCSPA------------- 907
            .:|...|.|:|||.  ....|...|.|..|.|||.|..||||.:|...|.|.
Zfish   410 REDPDLCEDIDECK--TPEICDQVCRNYEGGFECLCDEGYILQEDNYYCRPVEEDEHLTIQSADA 472

  Fly   908 ------LVGCPPGTQRSADGCAP-IECNPGYTLGSDDKCVDIDECQKQNGGCSHRCSNTEGSFKC 965
                  ||.....|:...|  || ||.:|.|.....:|..|.|...::       ...||.:|..
Zfish   473 TMNDPDLVTYASTTEWLTD--APSIEWHPTYPSWFTEKTEDGDVTTQE-------ADLTENAFSN 528

  Fly   966 SCPPGYELDSDQKTCQD--IDECDQDKTSCITGTCINEIGGFRCEFPKFPVLPEIPTASSLPESP 1028
            |  |.:.||..:...:|  |.....|..:.      ...|..|             |:.:|..:|
Zfish   529 S--PDHLLDITESNKEDEGISIATSDSVAA------RASGNKR-------------TSEALTSAP 572

  Fly  1029 KIELKTPKYPDFTELSNEIPENPKKPAEFDYPEPKFPSLPKWEGLPKLPPL 1079
            |   |...:...|..::::||:...|.....|..|......|..:..|.||
Zfish   573 K---KNRVFVMSTSATSQLPEDALAPGTQQRPGDKKKHDKSWLLVALLVPL 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
frac	NP_648137.3	FXa_inhibition	296..331	CDD:464251
		cEGF	396..415	CDD:463661
		FXa_inhibition	425..458	CDD:464251	4/11 (36%)
		FXa_inhibition	476..505	CDD:464251	7/28 (25%)
		EGF_CA	552..>581	CDD:214542	7/32 (22%)
		FXa_inhibition	596..630	CDD:464251	7/33 (21%)
		FXa_inhibition	636..>664	CDD:464251	8/49 (16%)
		EGF_CA	676..711	CDD:214542	16/36 (44%)
		FXa_inhibition	745..780	CDD:464251	14/34 (41%)
		FXa_inhibition	786..821	CDD:464251	14/34 (41%)
		vWFA	<821..861	CDD:469594	17/40 (43%)
		FXa_inhibition	874..904	CDD:464251	13/29 (45%)
		FXa_inhibition	945..980	CDD:464251	7/34 (21%)
		PTZ00449	<1017..>1098	CDD:185628	15/63 (24%)
		CCP	1110..1170	CDD:153056
		CCP	1183..1235	CDD:153056
		HYR	1468..1536	CDD:460572
cd248b	XP_021324763.1	CLECT	41..186	CDD:470576	35/185 (19%)
		FXa_inhibition	264..299	CDD:464251	16/58 (28%)
		cEGF	322..343	CDD:463661	11/20 (55%)
		vWFA	<338..372	CDD:469594	19/36 (53%)
		vWFA	<369..406	CDD:469594	16/38 (42%)
		EGF_CA	418..>447	CDD:214542	12/30 (40%)