DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment frac and fbln7

DIOPT Version :9

Sequence 1:NP_001137905.1 Gene:frac / 38850 FlyBaseID:FBgn0035798 Length:1618 Species:Drosophila melanogaster
Sequence 2:XP_001918972.3 Gene:fbln7 / 100000083 -ID:- Length:442 Species:Danio rerio


Alignment Length:469 Identity:118/469 - (25%)
Similarity:168/469 - (35%) Gaps:158/469 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   409 DCQDINECEVDGPEDLDNNAVCQQKCENTIGSFR----------CTCVEGYHLLEDQRSCALDSC 463
            ||.       |.|:.      |..| :..:|..|          ....||..:::.:       .
Zfish    18 DCN-------DAPQG------CMDK-QRVMGILRQMEKFLKGQEIRFTEGLRIMKSK-------L 61

  Fly   464 TDLEN-----PQLNRTRCAHECQDLPEGSYRCVCPKG-------YELSEDQHSCLVQESPCSTEK 516
            |:|:|     ||.:::.....|..|       |.|..       |.|..:.|      ..||  :
Zfish    62 TNLQNSVSKFPQADQSLSQSSCPPL-------VAPANGRKFGSKYLLGHEVH------FTCS--Q 111

  Fly   517 GVEKCSPGTCLASEDNTSFSCICPTGYRSEAFSCQDIDECAEDTHLCSHTCQNTPGGYQCQCPEG 581
            |.....|.|.:..|:.|         :.....||:|:..|:      |:.|||  ||   .|.|.
Zfish   112 GFRLVGPVTRVCQENGT---------WSGATASCKDVSMCS------SNPCQN--GG---TCVEA 156

  Fly   582 LNLVEEYTCLAENLCEVNNNG--CEQICLTA----------------------RGGVCACREGFR 622
            ||   :|.|    .|..|.:|  |:....||                      |...|:|..||.
Zfish   157 LN---KYKC----TCPYNWSGSQCQYQTQTAPPEWSVMNDPAFSRKPRCAKVDRAQHCSCDAGFH 214

  Fly   623 LS--ADGKSCEDVDECLV---NNGG--CQQVCRNLPGSYGCICAAGYELLKLDGIRGYCFDIDEC 680
            :|  :|...|:||:||.|   :.||  |...|.|:||||.|.|..||:|| .||  ..|.|:|||
Zfish   215 MSGTSDNSICQDVNECEVYKADRGGPLCVHACVNVPGSYHCSCPTGYKLL-ADG--RSCEDVDEC 276

  Fly   681 SQRTHGCSDQMLCENLNGSYTCL---CPPGYALGLDNHIVTSLNSSFITDSTSSETPSAHTC-LD 741
            ..:.|.||....|.|..|.:.|:   |||.:|           |:|::  .||......:.| ::
Zfish   277 LTQQHNCSRGSTCINTGGGFQCVSPECPPAHA-----------NASYV--KTSPLQCERNPCPME 328

  Fly   742 IDECSLANGNCSHFCQNEPGGFQCACPL-------------------GYALSEDMRTCQDIDECL 787
            ...|.||....|:...:.|...:....|                   |.|...|.|:...:..  
Zfish   329 SRSCPLAAKTISYHYLSLPSNLRTPATLFRMATASAPGRPGPDSLRFGIASGGDSRSLFVMQR-- 391

  Fly   788 DSNGQCSQLCLNQP 801
             |:.|..:|.|.||
Zfish   392 -SDRQTGELILVQP 404

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fracNP_001137905.1 FXa_inhibition 296..331 CDD:291342
cEGF 396..415 CDD:289433 2/5 (40%)
FXa_inhibition 425..458 CDD:291342 6/42 (14%)
FXa_inhibition 476..505 CDD:291342 7/35 (20%)
vWFA <550..586 CDD:294047 13/35 (37%)
FXa_inhibition 596..630 CDD:291342 13/59 (22%)
FXa_inhibition 636..>664 CDD:291342 15/32 (47%)
EGF_CA 676..715 CDD:284955 15/41 (37%)
FXa_inhibition 745..780 CDD:291342 10/53 (19%)
FXa_inhibition 786..821 CDD:291342 6/16 (38%)
FXa_inhibition 827..862 CDD:291342
FXa_inhibition 874..904 CDD:291342
FXa_inhibition 945..980 CDD:291342
CCP 1110..1170 CDD:153056
CCP 1183..1235 CDD:153056
DUF5011 1468..1536 CDD:295940
fbln7XP_001918972.3 CCP 83..137 CDD:153056 15/77 (19%)
EGF 142..172 CDD:278437 16/47 (34%)
vWFA <221..269 CDD:294047 23/50 (46%)
cEGF 252..275 CDD:289433 12/25 (48%)
EGF_CA 272..>302 CDD:284955 11/29 (38%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0002570
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24034
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
33.010

Return to query results.
Submit another query.