DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32374 and Prss55

DIOPT Version :9

Sequence 1:	NP_729270.1	Gene:	CG32374 / 38848	FlyBaseID:	FBgn0052374	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	XP_036014741.1	Gene:	Prss55 / 71037	MGIID:	1918287	Length:	347	Species:	Mus musculus

Alignment Length:	239	Identity:	68/239 - (28%)
Similarity:	111/239 - (46%)	Gaps:	18/239 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 TRIVNGKKIKCSRAPYQCALHYNNYFICGCVILNRRWILTAQHCKIG---NPGRYTVRAGSTQQR 133
            :||:.|::.:....|:|.::..:::..||..||:..||||..||...   :|....||.|:....
Mouse    59 SRIIEGQEAELGEFPWQVSIQESDHHFCGGSILSEWWILTVAHCFYAQELSPTDLRVRVGTNDLT 123

  Fly   134 RGGQLRHVQKTVCHPNYSEYTMKNDLCMMKLKTPLNVGRCVQKVKLPS-TRTKRFPKCYLASGWG 197
            .......|...:.|..:....|.||:.::.|..||........:.||. .....:.:|::| |||
Mouse   124 TSPVELEVTTIIRHKGFKRLNMDNDIALLLLAKPLTFNELTVPICLPLWPAPPSWHECWVA-GWG 187

  Fly   198 LT-SANAQNVQRYLRGVIVCKVSRAKCQQDYRGTGIKIYKQMICAKRKNR--DTCSGDSGGPLV- 258
            :| |.:.:::...|..|.:..:...:|.|.:.    .:...|:||...|.  |.|.||||||||
Mouse   188 VTNSTDKESMSTDLMKVPMRIIEWEECLQMFP----SLTTNMLCASYGNESYDACQGDSGGPLVC 248

  Fly   259 -----HNGVLYGITSFGIGCASAKYPGVYVNVLQYTRWIKKVAK 297
                 ......||.|:|..|....:||:|..:.:||.||:|:|:
Mouse   249 TTDPGSRWYQVGIISWGKSCGKKGFPGIYTVLAKYTLWIEKIAQ 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32374	NP_729270.1	Tryp_SPc	73..292	CDD:214473	64/231 (28%)
CG32374	NP_729270.1	Tryp_SPc	74..295	CDD:238113	65/233 (28%)
Prss55	XP_036014741.1	Tryp_SPc	60..287	CDD:214473	64/231 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910