DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32374 and Prss53

DIOPT Version :9

Sequence 1:	NP_729270.1	Gene:	CG32374 / 38848	FlyBaseID:	FBgn0052374	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	XP_006230384.1	Gene:	Prss53 / 499270	RGDID:	1566127	Length:	591	Species:	Rattus norvegicus

Alignment Length:	224	Identity:	60/224 - (26%)
Similarity:	92/224 - (41%)	Gaps:	21/224 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 SRAPYQCALHYNNYFICGCVILNRRWILTAQHCKIGNPGRYTVRAGSTQQRRGGQLRHVQKTVCH 147
            |:.|:...|.::....||..:::...:|||.||.|   ||.|:...|.....|.:...:::.:.|
  Rat   349 SQWPWDARLKHHGKLACGGALVSEVVVLTAAHCFI---GRQTLEEWSVGLGAGPEEWGLKQLILH 410

  Fly   148 PNYSEYTMKNDLCMMKLKTPLNVGRCVQKVKLPSTRTKRFPKCYLASGW--GLTSANAQN----V 206
            ..|:.....:|:..:.|..|:.:|..::.:.||.. ..|.|..  ..||  |||.....|    |
  Rat   411 GAYTHPEGGHDVAFLLLAQPVTLGPGLRPLCLPYA-DHRLPDG--EHGWVLGLTREAGINHPHTV 472

  Fly   207 QRYLRGVIVCKVSRAKCQQDYRGTGIKIYKQMICAKRKNRDT-CSGDSGGPLVH----NGVLYGI 266
            ...:.|.:.|....|..    ..||:.|...|||........ |.|.||.||||    ...|.|:
  Rat   473 PVTVLGPMACSRQHAAS----GSTGVPILPGMICTTVVGEPPHCEGLSGAPLVHEIRGTWFLAGL 533

  Fly   267 TSFGIGCASAKYPGVYVNVLQYTRWIKKV 295
            .|||..|..:..|.|:..:..|..|:..:
  Rat   534 HSFGDTCQGSAKPAVFAALSAYEDWVSNL 562

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32374	NP_729270.1	Tryp_SPc	73..292	CDD:214473	59/219 (27%)
CG32374	NP_729270.1	Tryp_SPc	74..295	CDD:238113	60/222 (27%)
Prss53	XP_006230384.1	Tryp_SPc	45..310	CDD:238113
Prss53	XP_006230384.1	Tryp_SPc	341..561	CDD:238113	60/221 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343304
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030