Protein Alignment CG32374 and F7

DIOPT Version :10

• Sequence 1: NP_729270.1
• Gene: CG32374 / 38848
• FlyBaseID: FBgn0052374
• Length: 299
• Species: Drosophila melanogaster
• Sequence 2: XP_011535776.2
• Gene: F7 / 2155
• HGNCID: 3544
• Length: 495
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 88/282 - (31%)
• Similarity: 126/282 - (44%)
• Gaps: 31/282 - (10%)

  Fly    38 LLYEGPRIKPQTFLP-GNISTNPAINALEAQDYLPTRIVNGKKIKCSRAPYQCALHYNNYFICGC 101
            ||.:|....|....| |.|......||.:.|.    |||.||.......|:|..|..|...:||.
Human   209 LLADGVSCTPTVEYPCGKIPILEKRNASKPQG----RIVGGKVCPKGECPWQVLLLVNGAQLCGG 269

  Fly   102 VILNRRWILTAQHC--KIGNPGRYTVRAGS---TQQRRGGQLRHVQKTVCHPNYSEYTMKNDLCM 161
            .::|..|:::|.||  ||.|........|.   ::.....|.|.|.:.:....|...|..:|:.:
Human   270 TLINTIWVVSAAHCFDKIKNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIAL 334

  Fly   162 MKLKTPLNVGRCVQKVKLP----STRTKRFPKCYLASGWG-LTSANAQNVQRYLRGVIVCKVSR- 220
            ::|..|:.:...|..:.||    |.||..|.:..|.|||| |....|..::     ::|..|.|
Human   335 LRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALE-----LMVLNVPRL 394

  Fly   221 --AKCQQDYR--GTGIKIYKQMICA--KRKNRDTCSGDSGGPLV--HNGVLY--GITSFGIGCAS 275
              ..|.|..|  |....|.:.|.||  ...::|:|.||||||..  :.|..|  ||.|:|.|||:
Human   395 MTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCAT 459

  Fly   276 AKYPGVYVNVLQYTRWIKKVAK 297
            ..:.|||..|.||..|::|:.:
Human   460 VGHFGVYTRVSQYIEWLQKLMR 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG32374	NP_729270.1	Tryp_SPc	73..292	CDD:214473	76/239 (32%)
F7	XP_011535776.2	GLA	36..97	CDD:214503
		EGF_CA	99..135	CDD:238011
		FXa_inhibition	180..216	CDD:464251	3/6 (50%)
		Tryp_SPc	242..478	CDD:238113	76/240 (32%)