DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32374 and f12

DIOPT Version :9

Sequence 1:	NP_729270.1	Gene:	CG32374 / 38848	FlyBaseID:	FBgn0052374	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	XP_017947702.2	Gene:	f12 / 100493769	XenbaseID:	XB-GENE-1004811	Length:	597	Species:	Xenopus tropicalis

Alignment Length:	325	Identity:	92/325 - (28%)
Similarity:	138/325 - (42%)	Gaps:	54/325 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 WILVVGGQSKNWSGYYVDNGTHYLLYEGPRIKPQTFLPGNISTNPAINALEAQDY---------L 70
            |..|:..|..:|....:...|.......|....:|..|...|.:.|.....:.|.         |
Frog   277 WCFVMKEQRLSWEHCLIPRCTQLAGTTAPPKVTKTPSPTKSSNHSASTPSPSNDTQGPVDGRIDL 341

  Fly    71 PT--------------RIVNGKKIKCSRAPYQCALHYNNYFICGCVILNRRWILTAQHCKIGNPG 121
            |.              |||.|.....:..||..||:.:|:| ||..:::..||:||.||....|.
Frog   342 PVDCGRKFQKTPSIMPRIVGGLVALPASHPYIAALYIDNHF-CGGSLISPCWIVTAAHCLDQRPN 405

  Fly   122 RYTVRAGSTQQRRGGQLRH-----VQKTVCHPNYSEYTMKNDLCMMKLKTPLNVGRC-------V 174
            ...:.....|.|.....:|     |:|.:.|..|...|:::|:.::|:|: :| |.|       |
Frog   406 VTKISVVLGQSRFNTTDQHTVTLLVEKYILHEKYYGDTLQHDIALVKVKS-IN-GLCASEFSQFV 468

  Fly   175 QKVKLP-----STRTKRFPKCYLASGWGLTSANAQNVQRYLRGVIVCKVSRAKCQQDYRGTGIKI 234
            |.:.||     :..||   :|.:| |||.....|::...:|:...:..:...:||.. ...|.::
Frog   469 QPICLPQQFKMAESTK---QCVVA-GWGHQYEGAEHYAFFLQEASMPIIPYTQCQSP-SVHGDRM 528

  Fly   235 YKQMICA--KRKNRDTCSGDSGGPLV--HNG--VLYGITSFGIGCASAKYPGVYVNVLQYTRWIK 293
            ...|:||  .....|.|.||||||||  .:|  .|:|:.|:|.|||....||||..|..||.||:
Frog   529 LPGMLCAGFMEGGVDACQGDSGGPLVCEVDGRIELHGVVSWGSGCAEENKPGVYTAVTSYTDWIR 593

Fly 294 293
Frog 594 593

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32374	NP_729270.1	Tryp_SPc	73..292	CDD:214473	77/241 (32%)
CG32374	NP_729270.1	Tryp_SPc	74..295	CDD:238113	78/243 (32%)
f12	XP_017947702.2	fn2	46..87	CDD:394995
		EGF_CA	95..129	CDD:238011
		KR	213..298	CDD:214527	4/20 (20%)
		Tryp_SPc	359..595	CDD:238113	78/243 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910