DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16998 and Prss36

DIOPT Version :9

Sequence 1:	NP_648134.1	Gene:	CG16998 / 38847	FlyBaseID:	FBgn0035795	Length:	258	Species:	Drosophila melanogaster
Sequence 2:	XP_017167884.1	Gene:	Prss36 / 77613	MGIID:	1924863	Length:	863	Species:	Mus musculus

Alignment Length:	261	Identity:	86/261 - (32%)
Similarity:	123/261 - (47%)	Gaps:	38/261 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LICGHKTSALSPQERIVGGVEVPIHLTPWLASITVHGNYSCSSALITSLWLVTAGHC------VQ 68
            |.||..    .|..|||||.:......||..|:...|.:.|..:||...|:::|.||      ::
Mouse    37 LDCGRP----EPSSRIVGGSDAHPGTWPWQVSLHQGGGHICGGSLIAPSWVLSAAHCFVTNGTLE 97

  Fly    69 YPDSYSVRAGSTFTDG---GGQRRNVVSVILHPDFNLRTLENDIALLKLDKSFTLGGNIQVVKLP 130
            ..|..||..|....||   |...|:|.::::..:::...|..|:|||:|.....||.:::.|.||
Mouse    98 PADELSVLLGVHSQDGPLEGAHMRSVATILIPDNYSTVELGADLALLRLASPAKLGPSVRPVCLP 162

  Fly   131 LPSLNILPRTLLVA-GWGNPDATDSESEPR---LRGTVVKVINQRLCQRLYSHLHRP-------- 183
            ..|......|...| |||  |..::...|.   |:...::::.:..||.|||   ||
Mouse   163 RASHLFAHGTACWATGWG--DVQEAVPLPLPWVLQEVELRLLGEAACQCLYS---RPGPFNLTFQ 222

  Fly   184 ITDDMVCA---AGAGRDHCYGDSGAPLV-HRGSSY---GIVSFAHGCADPHFPGVYTRLANYVTW 241
            :...|:||   ||. ||.|.||||.||| ..|..:   ||.||..||...:.|||:|.:|.|.:|
Mouse   223 LLPGMLCAGYPAGR-RDTCQGDSGGPLVCEDGGRWFLAGITSFGFGCGRRNRPGVFTAVAPYESW 286

  Fly   242 I 242
            |
Mouse   287 I 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16998	NP_648134.1	Tryp_SPc	24..242	CDD:214473	80/245 (33%)
CG16998	NP_648134.1	Tryp_SPc	25..242	CDD:238113	79/244 (32%)
Prss36	XP_017167884.1	Tryp_SPc	48..290	CDD:238113	81/246 (33%)
		Tryp_SPc	331..532	CDD:389826
		Tryp_SPc	607..789	CDD:389826
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010