DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16998 and Tmprss2

DIOPT Version :9

Sequence 1:	NP_648134.1	Gene:	CG16998 / 38847	FlyBaseID:	FBgn0035795	Length:	258	Species:	Drosophila melanogaster
Sequence 2:	NP_056590.2	Gene:	Tmprss2 / 50528	MGIID:	1354381	Length:	490	Species:	Mus musculus

Alignment Length:	252	Identity:	85/252 - (33%)
Similarity:	121/252 - (48%)	Gaps:	31/252 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 CGHKTSALSPQERIVGGVEVPIHLTPWLASITVHGNYSCSSALITSLWLVTAGHCVQYPDSYSVR 76
            ||  ..::..|.|||||:.......||..|:.|.|.:.|..::||..|:|||.|||:.|.| |.|
Mouse   243 CG--VRSVKRQSRIVGGLNASPGDWPWQVSLHVQGVHVCGGSIITPEWIVTAAHCVEEPLS-SPR 304

  Fly    77 AGSTFTDGG---------GQRRNVVSVILHPDFNLRTLENDIALLKLDKSFTLGGNIQVVKLPLP 132
            ..:.|  .|         |.|..|..||.||:::.:|..|||||:||.........::.|.||.|
Mouse   305 YWTAF--AGILRQSLMFYGSRHQVEKVISHPNYDSKTKNNDIALMKLQTPLAFNDLVKPVCLPNP 367

  Fly   133 SLNI-LPRTLLVAGWGNPDAT--DSESEPRLRGTVVKVINQRLC--QRLYSHLHRPITDDMVCAA 192
            .:.: |.:...::|||   ||  ..::...|...:|.:|....|  :.:|::|   ||..|:||.
Mouse   368 GMMLDLDQECWISGWG---ATYEKGKTSDVLNAAMVPLIEPSKCNSKYIYNNL---ITPAMICAG 426

  Fly   193 --GAGRDHCYGDSGAPLVHRGSS----YGIVSFAHGCADPHFPGVYTRLANYVTWIF 243
              ....|.|.||||.|||...:.    .|..|:..|||....||||..:..:..||:
Mouse   427 FLQGSVDSCQGDSGGPLVTLKNGIWWLIGDTSWGSGCAKALRPGVYGNVTVFTDWIY 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16998	NP_648134.1	Tryp_SPc	24..242	CDD:214473	80/237 (34%)
CG16998	NP_648134.1	Tryp_SPc	25..242	CDD:238113	79/236 (33%)
Tmprss2	NP_056590.2	LDLa	112..147	CDD:238060
		SRCR_2	152..247	CDD:373897	2/5 (40%)
		Tryp_SPc	254..485	CDD:238113	81/239 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910