DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG16998 and Klkb1

DIOPT Version :9

Sequence 1:	NP_648134.1	Gene:	CG16998 / 38847	FlyBaseID:	FBgn0035795	Length:	258	Species:	Drosophila melanogaster
Sequence 2:	NP_032481.2	Gene:	Klkb1 / 16621	MGIID:	102849	Length:	638	Species:	Mus musculus

Alignment Length:	252	Identity:	79/252 - (31%)
Similarity:	112/252 - (44%)	Gaps:	34/252 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 CGHKTSALSPQERIVGGVEVPIHLTPWLASI---TVHGNYSCSSALITSLWLVTAGHC---VQYP 70
            |..|.:|     |||||....:...||..|:   .|...:.|..::|...|::||.||   :.||
Mouse   383 CTTKINA-----RIVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYP 442

  Fly    71 DSYSVRAG----STFTDGGGQRRNVVSVILHPDFNLRTLENDIALLKLDKSFTLGGNIQVVKLP- 130
            |.:.:..|    |..|......| :..:|:|.::.:.....||||:||....    |....:.|
Mouse   443 DVWRIYGGILSLSEITKETPSSR-IKELIIHQEYKVSEGNYDIALIKLQTPL----NYTEFQKPI 502

  Fly   131 -LPS---LNILPRTLLVAGWGNPDATDSESEPRLRGTVVKVINQRLCQRLYSHLHRPITDDMVCA 191
             |||   .|.:.....|.|||. .....|::..|:...:.::....||:.|...  .|...|:||
Mouse   503 CLPSKADTNTIYTNCWVTGWGY-TKEQGETQNILQKATIPLVPNEECQKKYRDY--VINKQMICA 564

  Fly   192 A--GAGRDHCYGDSGAPLV--HRG--SSYGIVSFAHGCADPHFPGVYTRLANYVTWI 242
            .  ..|.|.|.||||.|||  |.|  ...||.|:..|||....|||||:::.|:.||
Mouse   565 GYKEGGTDACKGDSGGPLVCKHSGRWQLVGITSWGEGCARKDQPGVYTKVSEYMDWI 621

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG16998	NP_648134.1	Tryp_SPc	24..242	CDD:214473	74/238 (31%)
CG16998	NP_648134.1	Tryp_SPc	25..242	CDD:238113	73/237 (31%)
Klkb1	NP_032481.2	APPLE	21..104	CDD:128519
		APPLE	111..194	CDD:128519
		APPLE	201..284	CDD:128519
		APPLE	292..375	CDD:128519
		Tryp_SPc	390..621	CDD:214473	74/238 (31%)
		Tryp_SPc	391..621	CDD:238113	73/237 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910