Protein Alignment lqf and CLINT1

DIOPT Version :9

• Sequence 1: NP_729266.2
• Gene: lqf / 38846
• FlyBaseID: FBgn0028582
• Length: 831
• Species: Drosophila melanogaster
• Sequence 2: NP_001182484.1
• Gene: CLINT1 / 9685
• HGNCID: 23186
• Length: 643
• Species: Homo sapiens
• Alignment Length: 736
• Identity: 190/736 - (25%)
• Similarity: 302/736 - (41%)
• Gaps: 200/736 - (27%)

  Fly    21 NLAHNYSDAQVKVREATSNDPWGPSAAIMSEIAELTYNVVAFSEIMQMIWKR-LNDHGKNWRHVY 84
            |:..|||:.:.||||||::||||||..:|.|||:.|:....|.|:|.|:|.| |.|:.||||.||
Human    16 NVVMNYSEIESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPELMNMLWSRMLKDNKKNWRRVY 80

  Fly    85 KALILLEYLIKTGSEKVAQQCKENIFAIQTLREFVYFEE-GKDQGTHVREKAKQLVTLLKDDERL 148
            |:|:||.|||:.|||:|....:|:|:.:::|..:.:.:| |||||.::|:|.|:||...:||:||
Human    81 KSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEHGKDQGINIRQKVKELVEFAQDDDRL 145

  Fly   149 KNERVKAQKAKERF----AQNPSGFG-SDGYIDGPSQRDLPPGWQEEPPKSVSELEMVRPQTAGE 208
            :.||.||:|.|:::    :.:..||. |:.|...|..:     |.||..|:.|..    |.:...
Human   146 REERKKAKKNKDKYVGVSSDSVGGFRYSERYDPEPKSK-----WDEEWDKNKSAF----PFSDKL 201

  Fly   209 EELQLQLAMAMS------REEAEQEEAKRRSDDVRLQLALSQSEQDFKDPNGRPIPAPKKEEQQS 267
            .||..::...:.      |.:..::..:|.||          |:::.|...||......|:|:::
Human   202 GELSDKIGSTIDDTISKFRRKDREDSPERCSD----------SDEEKKARRGRSPKGEFKDEEET 256

  Fly   268 ------HLLDLLD---------------ISLGATS-----ISSPPLGAAGGAPTAVVDPWAMPGP 306
                  |:....:               |.|||.:     .:||...|:...|.:.|.. ::|..
Human   257 VTTKHIHITQATETTTTRHKRTANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKT-SVPSS 320

  Fly   307 RAPSQLSDPWSGTSSP---QVDPWN-----PSAAPRTILGAGVPMTSAPLGAGNDAWGARTQSPS 363
            ::...|.|.:.|||..   ..|.:.     .|||......:.|..||.....|:  |.|..|:||
Human   321 KSSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGD--WSAFNQAPS 383

  Fly   364 VASGSSNEGWLQSNGNANQNGRGATPAGPPAEGWLIKSTAVGALGAAPINHAANNGSSSSDPWLA 428
            ....||.|.:    |:|:|         |..|   :.|.:..|||..|   ||:|.|
Human   384 GPVASSGEFF----GSASQ---------PAVE---LVSGSQSALGPPP---AASNSS-------- 421

  Fly   429 EPAASAAGGAAAVGLADPWAPGAASQTGAGALDDPWKALGTGAIKKQSPEFDEFDLITNRNKSEH 493
                                                               |.|||:    .|..
Human   422 ---------------------------------------------------DLFDLM----GSSQ 431

  Fly   494 SNSNASNNNNASLLDDMDPLSANYGNGGINSSMHPSTGATAKKSIKDAHSFLGENSALVNLD-NL 557
            :...:|.:.|.|:      :|.|....|:..|        ..:.:::..:.|.:.:.|.|.: ::
Human   432 ATMTSSQSMNFSM------MSTNTVGLGLPMS--------RSQPLQNVSTVLQKPNPLYNQNTDM 482

  Fly   558 IKPIAPQT--QTGNQPAYNPFSDNVVPPKTNLFQQQQPAVPSINQLKQQAPFSVSMNQDPWAPVM 620
            ::....:|  .|.:.|:.|...||::|.    .|..:|..||:|.:.||......||      ||
Human   483 VQKSVSKTLPSTWSDPSVNISLDNLLPG----MQPSKPQQPSLNTMIQQQNMQQPMN------VM 537

  Fly   621 G---GVSTTSQPKLPPPVRPTSLNLGPSSVGEFQLLSALSNPIIPIAHIPQPQPNLQVYNNAYQS 682
            .   |....|.|....||||             |..:.:..|      :|...||:.........
Human   538 TQSFGAVNLSSPSNMLPVRP-------------QTNALIGGP------MPMSMPNVMTGTMGMAP 583

  Fly   683 SSSTNILGKSNIPTNMNSSTS 703
            ..:|.::.:|.:..|||...|
Human   584 LGNTPMMNQSMMGMNMNIGMS 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lqf	NP_729266.2	ENTH_epsin	28..149	CDD:239627	59/122 (48%)
		UIM	208..227	CDD:197845	3/24 (13%)
CLINT1	NP_001182484.1	ENTH_EpsinR	24..149	CDD:340786	60/124 (48%)
		Nucleoporin_FG	329..407	CDD:372653	25/95 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263849at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2102
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.950