Protein Alignment lqf and ENT2

DIOPT Version :9

• Sequence 1: NP_729266.2
• Gene: lqf / 38846
• FlyBaseID: FBgn0028582
• Length: 831
• Species: Drosophila melanogaster
• Sequence 2: NP_013307.1
• Gene: ENT2 / 850903
• SGDID: S000004196
• Length: 613
• Species: Saccharomyces cerevisiae
• Alignment Length: 729
• Identity: 172/729 - (23%)
• Similarity: 254/729 - (34%)
• Gaps: 222/729 - (30%)

  Fly    17 RNIKNLAHNYSDAQVKVREATSNDPWGPSAAIMSEIAELTYNVVAFSEIMQMIWKRLNDHGKNWR 81
            |:.||:...||..||.||:||:||...||...:.::|:.:|:.|.|.|||.|:.|||||.||.||
Yeast     7 RSAKNMMKGYSSTQVLVRDATANDSRTPSIDTLDDLAQRSYDSVDFFEIMDMLDKRLNDKGKYWR 71

  Fly    82 HVYKALILLEYLIKTGSEKVAQQCKENIFAIQTLREFVY-FEEGKDQGTHVREKAKQLVTLLKDD 145
            ||.|:|.:|:||::.|||.....|:||.:.|:|||||.: .|.|.|:|..:|.|||:||:||.|:
Yeast    72 HVAKSLTVLDYLVRFGSENCVLWCRENFYVIKTLREFRHENESGFDEGQIIRVKAKELVSLLNDE 136

  Fly   146 ERLKNERV------KAQKA------KERFAQNPSGFGSDGYIDGPSQRDLPPGWQEEPPKSVSEL 198
            |||:.||.      :|.:|      ::|...||              .|..|.:|::..|::.|
Yeast   137 ERLREERSMNTRNRRANRAARPRPRRQRTRSNP--------------HDSSPSYQDDLEKALEE- 186

  Fly   199 EMVRPQTAGEEELQLQLAMAMSREEAEQEEAKRRSDDVRLQLALSQSEQDFKDPNGR-PIPAPKK 262
                                 ||..|:::|.:||      :||    :.|.:||:.: .:...|:
Yeast   187 ---------------------SRITAQEDEQRRR------ELA----QYDDEDPDFQAALQLSKE 220

  Fly   263 EEQQSHLLDLLDISLGATSISSPPLGAAGGAPTAVVDPWAMPGPRAPSQLSDPWSGTSSPQVDPW 327
            ||:...|.:|..:.....|:|.                     .:||.|       ...||..|
Yeast   221 EEELKQLQELQRLQKQQQSLSQ---------------------FQAPLQ-------QQQPQQQP- 256

  Fly   328 NPSAAPRTILGAGVPMTSAPLGAGNDAWGARTQSPSVASGSSNEGWLQSNGNANQNGRGATPAGP 392
                |...|.|..:         ..|.:.............:.:.||.......|
Yeast   257 ----AYYDIFGNPI---------SQDEYLQYQYQQDQEQAMAQQRWLDQQQEQQQ---------- 298

  Fly   393 PAEGWLIKSTAVGALGAAPINH---AANNGSSSSDPWLAEPAASAAGGAAAVGLADPWAPGAASQ 454
            .||....:.....|..|:.:..   |||.......|               .....|...|:.:.
Yeast   299 LAEQQYFQQQQQAAAAASALQQQQTAANMQQQQQQP---------------ADFQQPLPTGSNNP 348

  Fly   455 TGAGALDDPWKALGTGAIKKQSPEF----DEFDL-ITNRNKSEHSNSNASNNNNASL-------- 506
            .....|:...:......:::|..|.    ::..| ...|.:.|.:..:......|.|
Yeast   349 FSMDNLERQKQEQQHAQLQRQQEEARQQQEQLKLQQLQRQQQEEAQLHQKRQEEAQLQQQQAQLL 413

  Fly   507 -----LDDMDPLSANYGNGGINSSMHPSTGATAKKSIKDAHS----FLGENSALVNLDNLIKPIA 562
                 .....||...               .|..:||.|.:|    .|...:.:....|..:...
Yeast   414 QQQAQFQQQQPLKQT---------------RTGNQSISDKYSDLNTLLATGTGIDTFGNTGEARI 463

  Fly   563 P--QTQTG--------------NQPAYNPF---------SDNVVPPKTNLFQQQQPAVPSINQLK 602
            |  .|:||              |:|..|||         |.|:||.:|......||..|..|. .
Yeast   464 PAQHTKTGTFINSQGTGYKQVTNEPKNNPFLSNQYTGLPSTNIVPTQTGYGFGNQPQSPPTNS-P 527

  Fly   603 QQAPFSVSMNQDPWAPVMGGVSTTSQPKLPPPVRPTSLNLGPSSVGEFQLLSALSNPIIPIAHIP 667
            ||.|..:|.:|.         ....||:..|..........|.....||               .
Yeast   528 QQNPTGISYSQP---------QQQQQPQQQPQYMQNFQQQQPQYAQNFQ---------------Q 568

  Fly   668 QPQPNLQVYNNAYQ 681
            |||     |...||
Yeast   569 QPQ-----YTQNYQ 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lqf	NP_729266.2	ENTH_epsin	28..149	CDD:239627	61/121 (50%)
		UIM	208..227	CDD:197845	3/18 (17%)
ENT2	NP_013307.1	ENTH_Ent1_Ent2	15..145	CDD:340788	66/129 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343620
Domainoid	1	1.000	124	1.000	Domainoid score	I1203
eggNOG	1	0.900	-	-		E1_KOG2056
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	176	1.000	Inparanoid score	I975
Isobase	1	0.950	-	0	Normalized mean entropy	S1984
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000780
OrthoInspector	1	1.000	-	-		otm46894
orthoMCL	1	0.900	-	-		OOG6_103058
Panther	1	1.100	-	-	O	PTHR12276
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2102
SonicParanoid	1	1.000	-	-		X540
TreeFam	1	0.960	-	-
	14	13.730