DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment lqf and AT5G11710

DIOPT Version :9

Sequence 1:	NP_729266.2	Gene:	lqf / 38846	FlyBaseID:	FBgn0028582	Length:	831	Species:	Drosophila melanogaster
Sequence 2:	NP_001318545.1	Gene:	AT5G11710 / 831043	AraportID:	AT5G11710	Length:	560	Species:	Arabidopsis thaliana

Alignment Length:	593	Identity:	143/593 - (24%)
Similarity:	234/593 - (39%)	Gaps:	153/593 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 DDMQV---NVAGLRRNIKNLAHNYSDAQVKVREATSNDPWGPSAAIMSEIAELTYNVVAFSE--- 64
            |.|:|   .|..::|.:........:.:.||.:||.|:||||....::|||:.|..   |||
plant     2 DFMKVFDQTVREIKREVNLKVLKVPEMEQKVLDATDNEPWGPHGTALAEIAQATKK---FSECQM 63

  Fly    65 IMQMIWKRLNDHGKNWRHVYKALILLEYLIKTGSEKVAQQCKENIFAIQTLREFVYFE-EGKDQG 128
            :|.::|.||::.||:||:|||||.:::|||..|||:...:..|:.:.|.:|..|.|.| .|||.|
plant    64 VMSVLWTRLSETGKDWRYVYKALAVIDYLISNGSERAVDEIIEHTYQISSLTSFEYVEPNGKDVG 128

  Fly   129 THVREKAKQLVTLLKDDERLKNERVKAQKAKERF-----------AQNPSGFGS---------DG 173
            .:||:||:.:|.||.:.|::...|.||...:.::           :.:.:.||.         |.
plant   129 INVRKKAENIVALLNNKEKISEIRDKAVANRNKYVGLSSTGITYKSGSSASFGGSFQSGSSNFDS 193

  Fly   174 YIDGPSQRDLPP---------GWQEEPPKSVSELEMVRPQTAGEEELQLQLAMAMSREEAEQEEA 229
            |.|..|:.|...         |.:.|.....|:....|..:...:.|        |..:...:.|
plant   194 YKDRDSREDKNDYESFQKSRRGVKTEEQSYTSKKSFSRYGSTDHDNL--------SSGKKSPDSA 250

  Fly   230 KRRSDDVRLQLALSQSEQDFKDPNGRPIPAPKKEEQQSHLLDLL--------------------- 273
            |.||   .:..|.|.::.||.|.:.|...:.|.....::.:||.
plant   251 KHRS---YVSAAPSNNDDDFDDFDPRGTSSNKPSTGSANQVDLFGGDLIGDFLDSGPTETSSTNN 312

  Fly   274 -------DISLGATSISSPPLGAAGGAPT-AVVDPWAMPGP-----RAP---------------- 309
                   |:...|..:|:...||..|:.| ..||.::...|     .||
plant   313 NENFQEADLFADAAFVSASAQGAEFGSQTQKQVDLFSASEPSVTVSSAPPTVDLFASSESVVSPE 377

  Fly   310 SQLSDPWSGTSSPQVDPWNPSAAPRTILGAGVPMTSAPLGAGNDAWGART----------QSPSV 364
            :::|.|.|..:...|||:           |.|||.:..   |:|.:||.|          |:|||
plant   378 AKISIPESMATPNIVDPF-----------AAVPMDNFD---GSDPFGAFTSHSASVSTGPQAPSV 428

  Fly   365 -ASGSSNEGWLQSNGNANQNGRGATPAGPPAEGWLIKSTAVGALGAAPINHAANNGSSSSDPWLA 428
             .|.::....|....:..|:.:...|....:..|....:.    |...:|..|...:|.:|..:.
plant   429 HGSATNTTSPLSFADSKPQHLQKKDPFQVKSGIWADSLSR----GLIDLNITAPKKASLADVGVV 489

  Fly   429 EPAASAAGG-AAAVGLADPWAPGAASQTGAGALDDPWKALGTGAI----------KKQSPEF--D 480
            ...::..|. |:|......|:.||.|..|.           ||..          ::|:|:.  |
plant   490 GDLSNEDGNKASAASYYSGWSMGAGSGLGK-----------TGLYSTQQQQQQQQQQQAPDISDD 543

  Fly   481 EFDLITNR 488
            .|..::|:
plant   544 FFSSLSNQ 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
lqf	NP_729266.2	ENTH_epsin	28..149	CDD:239627	53/124 (43%)
lqf	NP_729266.2	UIM	208..227	CDD:197845	2/18 (11%)
AT5G11710	NP_001318545.1	ENTH	28..144	CDD:340772	52/118 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	126	1.000	Domainoid score	I1773
eggNOG	1	0.900	-	-		E1_KOG2056
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	138	1.000	Inparanoid score	I1811
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3510
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12276
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X540
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.920