Protein Alignment lqf and Epn3

DIOPT Version :10

• Sequence 1: NP_729266.2
• Gene: lqf / 38846
• FlyBaseID: FBgn0028582
• Length: 831
• Species: Drosophila melanogaster
• Sequence 2: NP_082260.1
• Gene: Epn3 / 71889
• MGIID: 1919139
• Length: 636
• Species: Mus musculus
• Alignment Length: 712
• Identity: 274/712 - (38%)
• Similarity: 374/712 - (52%)
• Gaps: 149/712 - (20%)

  Fly    10 VNVAGLRRNIKNLAHNYSDAQVKVREATSNDPWGPSAAIMSEIAELTYNVVAFSEIMQMIWKRLN 74
            :..:.|||.:||:.||||:|::|||||||||||||.:::|||||:||:|.|||:|:|.|:|:|||
Mouse     1 MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFAEVMGMVWRRLN 65

  Fly    75 DHGKNWRHVYKALILLEYLIKTGSEKVAQQCKENIFAIQTLREFVYFE-EGKDQGTHVREKAKQL 138
            |.|||||||||||.||:||:|||||:||.||:||::.||||::|.|.: :|||||.:||||.||:
Mouse    66 DSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVNVREKVKQV 130

  Fly   139 VTLLKDDERLKNERVKAQKAKERFAQNPSGFGSD--GYIDGPSQRDLPPGW--QEEPPKSVSELE 199
            :.||||:|||:.||..|.|.|||.|....|.||.  ||  ....|..|..:  ....|:..|:||
Mouse   131 MALLKDEERLRQERTHALKTKERMALEGMGIGSGQLGY--SRRSRGSPSSYTSASSSPRYASDLE 193

  Fly   200 MVRPQTAGEEELQLQLAMAMSREEAEQ--EEAKRRSDDVRLQLALSQSEQDFK------------ 250
            ..||||:||||||||||:||||||||:  ..|..|.:|::||||||.|.|:.:
Mouse   194 QARPQTSGEEELQLQLALAMSREEAERPVPPASHRDEDLQLQLALSLSRQEHEKGVRSWKGDDSP 258

  Fly   251 -----DPNGR-------PIPAPKKEEQ-----QSHLLDLLDISLGATSISSPPLGAAGGAPTAVV 298
                 :|.|:       |....:|||:     ||.:|||.||...|.::.|....|
Mouse   259 VANGAEPAGQRRQRDREPEREERKEEEKLKTSQSSILDLADIFAPAPALPSTHCSA--------- 314

  Fly   299 DPWAMPGPRAPSQLSDPWSGTSSPQVDPWNPSAAPRTILGAGVPMTSAPLGAGNDAWGARTQS-- 361
            |||.:||.| |:  ::|...:..|..|||:|           ||       :||..  :|:|.
Mouse   315 DPWDIPGLR-PN--TEPSGSSWGPSADPWSP-----------VP-------SGNAL--SRSQPWD 356

  Fly   362 --PSVASGSSNEGWLQSNGNANQNGR-GATPAGPP-AEGWLIKSTAVGALGAAPINHAANNGSSS 422
              |::   ||:|.|          || ...|:||| |:.|            ||.:......|:.
Mouse   357 LLPTL---SSSEPW----------GRTPVLPSGPPIADPW------------APSSPTRKLPSTG 396

  Fly   423 SDPW---LAEPAASAAGGAAAVGLADPWAPGAASQTGAGALDDPWKALGTGAIKKQSPEFDEFDL 484
            :|||   :.....||.|||:..   ||:|....| |......|..:||.||    :||...|.|
Mouse   397 ADPWGASMETSDTSALGGASPF---DPFAKPLES-TEPKESRDSAQALPTG----KSPSTVELD- 452

  Fly   485 ITNRNKSEHSNSNASNNNNASLLDDMDPLSANYGNGGINSSMHPSTGATAKKSIKDAHSFLGEN- 548
                   ...:|:.|...|..    .:|.:.:.|..|......|...|   :..:...||||.:
Mouse   453 -------PFGDSSPSCKQNGM----KEPEALDLGVLGEALPQQPGKEA---RPCRTPESFLGPSA 503

  Fly   549 SALVNLDNLIK-PIAPQTQTGNQPAYNPFSDNV-VPPKTNLFQQQQPAVPSINQLKQQAPFSVSM 611
            |:|||||:|:| |:|.:|:       |||...: ||..||.|.......|::||::..:|   ::
Mouse   504 SSLVNLDSLVKAPLAARTR-------NPFLTGLGVPSPTNPFGAGDQGRPTLNQMRTGSP---AL 558

  Fly   612 NQDPWAPVMGGV-STTSQPKLPPPVRPTSLNLG---PSSVGEFQLLSALSNPIIPIAHIPQP 669
            ...|..||...| |.|....||.|:  :|:.:|   |:||..|....|.:.|  | |.:|||
Mouse   559 GLPPGGPVGAPVGSMTYSASLPLPL--SSVPVGATLPASVSVFPQAGAFAPP--P-ASLPQP 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lqf	NP_729266.2	ENTH_Epsin	28..150	CDD:340787	83/122 (68%)
		UIM	208..227	CDD:197845	17/20 (85%)
		PHA03247	<278..394	CDD:223021	33/121 (27%)
Epn3	NP_082260.1	ENTH_Epsin	19..142	CDD:340787	83/122 (68%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	153..503		131/431 (30%)
		UIM	202..221	CDD:197845	17/18 (94%)
		PHA03247	<302..634	CDD:223021	117/409 (29%)
		5 X 3 AA repeats of [DE]-P-W	315..400		36/132 (27%)
		3 X 3 AA repeats of N-P-F	523..635		34/101 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	607..636		6/12 (50%)