Protein Alignment lqf and epn2

DIOPT Version :9

• Sequence 1: NP_729266.2
• Gene: lqf / 38846
• FlyBaseID: FBgn0028582
• Length: 831
• Species: Drosophila melanogaster
• Sequence 2: NP_001006853.1
• Gene: epn2 / 448609
• XenbaseID: XB-GENE-22060525
• Length: 579
• Species: Xenopus tropicalis
• Alignment Length: 709
• Identity: 281/709 - (39%)
• Similarity: 356/709 - (50%)
• Gaps: 188/709 - (26%)

  Fly    10 VNVAGLRRNIKNLAHNYSDAQVKVREATSNDPWGPSAAIMSEIAELTYNVVAFSEIMQMIWKRLN 74
            :..:.:||.:||:.:|||:|::||||||||||||||:::|:|||:||||||||||||.|||||||
 Frog     1 MTTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMIWKRLN 65

  Fly    75 DHGKNWRHVYKALILLEYLIKTGSEKVAQQCKENIFAIQTLREFVYFE-EGKDQGTHVREKAKQL 138
            |||||||||||||.||:||||||||:|:.||||||||||||::|.|.: :|||||.:||||:|||
 Frog    66 DHGKNWRHVYKALTLLDYLIKTGSERVSHQCKENIFAIQTLKDFQYMDRDGKDQGINVREKSKQL 130

  Fly   139 VTLLKDDERLKNERVKAQKAKERFAQNPSGFGSDGYID---GPSQRDLPPGWQEE---------- 190
            |.|||||||||.||.:|.|.|||.||..:|..|:..|.   |.||.:|...:.|:
 Frog   131 VCLLKDDERLKGERAQALKTKERMAQVATGVSSNNQITFGRGSSQPNLSTSYSEQDYGKSGGSPA 195

  Fly   191 ------PPKSVSELEMVRPQTAGEEELQLQLAMAMSREEAEQEEAKRRSDDVRLQLALSQSEQDF 249
                  .|:..||||..||||:||||||||||:|||||.|||||..||.||:|||:||.:|.:
 Frog   196 SYHGSTSPRVSSELEQARPQTSGEEELQLQLALAMSREVAEQEERIRRGDDLRLQMALEESRK-- 258

  Fly   250 KDPNGRPIPAP-KKEEQQSHLLDLLD-ISLGATSISSPPLGAAGGAPTAVVDPWAMPGPRAPSQL 312
                 ..|.|| ||.:||:.|||||| :..||.:...|...||..|..:..|||.:... :||.
 Frog   259 -----HTIKAPRKKAQQQTTLLDLLDALPSGAPAPQKPDTWAAAVATKSKSDPWNVAAV-SPSS- 316

  Fly   313 SDPW----SG--TSSPQVDPWNPSAAPRTILGAGVPMTSAPLGAGNDAWGARTQSPSVASGSSNE 371
            ||||    ||  |::|| |||...|.|.|          ..|...:|.|
 Frog   317 SDPWQSFGSGTKTAAPQ-DPWGGKAGPST----------QSLSKNSDPW---------------- 354

  Fly   372 GWLQSNGNANQNGRGATPAGPPAEGWLIKSTAVGALGAAPINHAANNGSSSSDPWLAEPAASAAG 436
                           :||                        .||...||.:|||.|.|...
 Frog   355 ---------------STP------------------------KAAGIASSPTDPWGATPQVK--- 377

  Fly   437 GAAAVGLADPWAPGAASQTGAGALD-DPWKALGTGAIKKQSPEFDEFDLITNRNKSEHSNSNASN 500
                           |:.:.||.|. ||:..| .|..|....|||  .|.|:...|..|||...:
 Frog   378 ---------------ANMSNAGGLAFDPFSNL-NGTAKDDLSEFD--SLRTSSKVSADSNSTLPS 424

  Fly   501 NNNASLLDDMDPLSANYGNGGINSSMHPSTGATAKKSIKDAHSFLGENSALVNLDNLIKPIAPQT 565
            ..:.:...|:  .::...|  :.||...|...|.:       ||||.|:|||||:.|:....|..
 Frog   425 LRSGTTSPDL--FASKPDN--VTSSKQTSVRKTPE-------SFLGSNAALVNLETLVSMPPPAA 478

  Fly   566 QTGNQPAYNPF-----SDNVVPPKTNLFQQQQPAVPSINQLKQQAPFSVSMNQDPWAPVMG-GVS 624
                 |..|||     :.....|..|.||..||...::|||:.             :|:|| |..
 Frog   479 -----PILNPFLASGAATTTTTPPVNPFQVNQPQALTLNQLRS-------------SPMMGAGAE 525

  Fly   625 TTSQPKLPPP-------VRPTSLN---------------LGPSSVGEFQLLSALSNPII 661
            ..|  .:|||       ..||.|.               :.|||.   |.::| :||.:
 Frog   526 PLS--SVPPPGMSTLPAAHPTGLGININMAATLPHHSTAMAPSST---QAVNA-TNPFL 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lqf	NP_729266.2	ENTH_epsin	28..149	CDD:239627	96/121 (79%)
		UIM	208..227	CDD:197845	16/18 (89%)
epn2	NP_001006853.1	ENTH_Epsin	19..141	CDD:340787	96/121 (79%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	214	1.000	Domainoid score	I2684
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	379	1.000	Inparanoid score	I2022
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263849at2759
OrthoFinder	1	1.000	-	-		FOG0000780
OrthoInspector	1	1.000	-	-		otm49026
Panther	1	1.100	-	-	O	PTHR12276
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2102
SonicParanoid	1	1.000	-	-		X540
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.100